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Items: 1 to 20 of 647

1.

Differential contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in vivo renal uptake of uremic toxins in rats.

Deguchi T, Kouno Y, Terasaki T, Takadate A, Otagiri M.

Pharm Res. 2005 Apr;22(4):619-27. Epub 2005 Apr 7.

PMID:
15846470
2.

Characterization of uremic toxin transport by organic anion transporters in the kidney.

Deguchi T, Kusuhara H, Takadate A, Endou H, Otagiri M, Sugiyama Y.

Kidney Int. 2004 Jan;65(1):162-74.

3.

Involvement of organic anion transporters in the efflux of uremic toxins across the blood-brain barrier.

Deguchi T, Isozaki K, Yousuke K, Terasaki T, Otagiri M.

J Neurochem. 2006 Feb;96(4):1051-9.

4.

Contribution of organic anion transporters to the renal uptake of anionic compounds and nucleoside derivatives in rat.

Hasegawa M, Kusuhara H, Endou H, Sugiyama Y.

J Pharmacol Exp Ther. 2003 Jun;305(3):1087-97. Epub 2003 Mar 26.

5.

Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity.

Enomoto A, Takeda M, Tojo A, Sekine T, Cha SH, Khamdang S, Takayama F, Aoyama I, Nakamura S, Endou H, Niwa T.

J Am Soc Nephrol. 2002 Jul;13(7):1711-20.

6.

Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney.

Deguchi T, Ohtsuki S, Otagiri M, Takanaga H, Asaba H, Mori S, Terasaki T.

Kidney Int. 2002 May;61(5):1760-8.

7.

Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier.

Kikuchi R, Kusuhara H, Sugiyama D, Sugiyama Y.

J Pharmacol Exp Ther. 2003 Jul;306(1):51-8. Epub 2003 Apr 8.

8.

Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus.

Nagata Y, Kusuhara H, Endou H, Sugiyama Y.

Mol Pharmacol. 2002 May;61(5):982-8.

9.

Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions.

Hasegawa M, Kusuhara H, Sugiyama D, Ito K, Ueda S, Endou H, Sugiyama Y.

J Pharmacol Exp Ther. 2002 Mar;300(3):746-53.

11.

Restored expression and activity of organic ion transporters rOAT1, rOAT3 and rOCT2 after hyperuricemia in the rat kidney.

Habu Y, Yano I, Okuda M, Fukatsu A, Inui K.

Biochem Pharmacol. 2005 Mar 15;69(6):993-9.

PMID:
15748710
12.

Species differences of organic anion transporters involved in the renal uptake of 4-amino-3-chlorophenyl hydrogen sulfate, a metabolite of resatorvid, between rats and dogs.

Takeuchi T, Jinno F, Ebihara T, Moriya Y, Kadotani R, Tagawa Y, Kondo T, Itoh T, Asahi S.

Biopharm Drug Dispos. 2013 May;34(4):236-46. doi: 10.1002/bdd.1841. Epub 2013 May 7.

PMID:
23529922
13.

Renal disposition of a furan dicarboxylic acid and other uremic toxins in the rat.

Tsutsumi Y, Deguchi T, Takano M, Takadate A, Lindup WE, Otagiri M.

J Pharmacol Exp Ther. 2002 Nov;303(2):880-7.

14.

Decreased activity of basolateral organic ion transports in hyperuricemic rat kidney: roles of organic ion transporters, rOAT1, rOAT3 and rOCT2.

Habu Y, Yano I, Takeuchi A, Saito H, Okuda M, Fukatsu A, Inui K.

Biochem Pharmacol. 2003 Sep 15;66(6):1107-14.

PMID:
12963498
15.

Effects of uremic toxins on hepatic uptake and metabolism of erythromycin.

Sun H, Huang Y, Frassetto L, Benet LZ.

Drug Metab Dispos. 2004 Nov;32(11):1239-46. Epub 2004 Jul 30.

16.

Roles of inner blood-retinal barrier organic anion transporter 3 in the vitreous/retina-to-blood efflux transport of p-aminohippuric acid, benzylpenicillin, and 6-mercaptopurine.

Hosoya K, Makihara A, Tsujikawa Y, Yoneyama D, Mori S, Terasaki T, Akanuma S, Tomi M, Tachikawa M.

J Pharmacol Exp Ther. 2009 Apr;329(1):87-93. doi: 10.1124/jpet.108.146381. Epub 2008 Dec 30.

17.

Characterization of the uptake of organic anion transporter (OAT) 1 and OAT3 substrates by human kidney slices.

Nozaki Y, Kusuhara H, Kondo T, Hasegawa M, Shiroyanagi Y, Nakazawa H, Okano T, Sugiyama Y.

J Pharmacol Exp Ther. 2007 Apr;321(1):362-9. Epub 2007 Jan 25.

18.

Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells.

Mori S, Takanaga H, Ohtsuki S, Deguchi T, Kang YS, Hosoya K, Terasaki T.

J Cereb Blood Flow Metab. 2003 Apr;23(4):432-40.

19.

The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules.

Imaoka T, Kusuhara H, Adachi-Akahane S, Hasegawa M, Morita N, Endou H, Sugiyama Y.

J Am Soc Nephrol. 2004 Aug;15(8):2012-22.

20.

Carrier-mediated uptake of H2-receptor antagonists by the rat choroid plexus: involvement of rat organic anion transporter 3.

Nagata Y, Kusuhara H, Hirono S, Endou H, Sugiyama Y.

Drug Metab Dispos. 2004 Sep;32(9):1040-7.

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