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15820315,16280085,14962980,15634360,11101841,9412790,8630505,1303277,11779183,10712201,9354807,9590284,25482058,22496793,8388169,11701647,1303276,16397868,8188222,16002520,10508517,20092561,15288352,17036336,17095305,17159828,17268193,9365529,11845283,12944418,14694357,7987392,18226259,15151506,9237260,15459179,16190961,9174400,14749005,19278672,11306815,25378697,12920063,10101947,16819717,16368707,19712904,10556298,20083560,16575192,11242121,9674903,11350123,11106375,10469839,8841186,9634532,7512861,15337472,1338769,14508708,8825647,9302265,15115105,24704109,1303278,20803659,18627066,15807298,23390487,7849716,10514831,20304067,9401540,32961075,19207281,20195375,11258349,10740202,10783265,28024084,23918391,16075369,17728320,2568752,2564739,20136683,11424049,21343540,8095339,15367489,8872029,26335514,10422004,27659713,16451133,15668048,14693421,12410230,24127921,10430930,8958335,10400982,10626556,19159549,15877813,19293572,9121208,20588305,22529396,19697784,17236194,12558108,2750788,15978509,8723064,8755558,17337158,20981773,9691003,2309781,18554170,9102354,11157801,11417368,11431693,32474395,16455231,8886165,11464243,33807162,9477342,28004416,14634983,16178933,16011554,10915770,32329685,17978792,19302470,21659337,18279435,29437285,35955861,10936046,12971993,14700141,20575009,7611294,23295077,12545427,21735174,9110176,11592036,18324689,25531260,10797418,17626606,18500341,10701104,23391702,18835857,17055193,12704708,17537073,17303379,9613204,20727826,11421188,16575193,21971015,23303386,9063754,12626835,30102380,17339270,11809260,9601023,32578144,26848093,12045206,15373217,9580159,10332034,15744456,8364575,30904443,12411498,10229769,22694955,11007541,7633438,29352661,26824232,11579432,18752349,12840045,11259587,7705658,27153221,15617548,17262171,22122080,8614834,11180221,12558118,11352560,9465079,15779004,30988409,10640832,11260224,21840925,29228278,18726118,31087031,1427794,15565282,9933566,9500470,11076044,9500535,10318933,15109994,12843450,25832033,29433608,23296430,1714232,2812027,8421497,35688807,8188218,20082457,23686718,14723660,11935334,19760168,10775525,36901699,23697931,10860668,25300248,7761348,24816254,24039599,30003711,22289342,12843457,22043168,18627056,11425004,12627233,1611213,35842787,15578038,11310581,22331910,24363065,14511934,15965783,15305064,24737477,12952863,31964399,31698873,36674736,9838852,12154412,9215770,24945811,30124848,30902571,18266248,11057133,31638013,34417445,36190479,18698613,11596444,15459175,25246219,11528397,17506103,11840190,15094299,11352562,19066619,15666333,26446116,29425059,14723659,12372053,26002101,16801186,26040449,19894069,1448175,32121146,14962665,29800646,17043311,11900479,30793526,1685485,21233802,20560980,20020165,27777904,31991769,32426821,19763929,16429232,20837313,33116122,20016068,9697691,16575184,2151033,20635407,15585606,12951183,7490098,9328477,27799465,24076603,7580867,15138197,31268171,15355442,9018447,12032310,28296079,10395905,15014969,10196368,28111641,2777249,35442499,22642890,11076053,20461108,23208756,12439903,17848516,34389046,28296064,10585772,20675686,28266014,12584540,18320030,34238473,32630716,31353046,15208369,7585867,15175115,20956530,12702163,10343092,11318613,12461650,9630521,31920975,1608955,31791363,35203049,11027108,12819139,26365340,33895503,19506242,8889594,12818083,17893678,18166085,23771028,16470700,15465498,15820313,37068109,27789403,17932619,18039333,20920489,20708498,8902605,11156619,24916642,18533099,34040195,25003016,25962248,32420597,10196367,25343115,9843055,8639158,9375847,11115855,11782285,1845916,12843444,34238471,27537837,20880323,15634324,16855283,15567729,20542394,30820248,22127900,15327781,2032723,22256610,15754036,25172960,22495932,3012567,11503444,11489053,11935319,18085265,12915446,23609791,12843449,19517793,32922110,17103438,2090424,8542279,11745993,12843440,24866188,28857689,16309881,11279514,11424354,20394819,28009282,32384786,30353709,8824812,29691382,27871485,35316681,27672097,15212237,28933382,2328988,32804975,16575188,12920789,36084040,31687254,16575168,10508501,9702082,11829485,20876615,14709593,7781998,24482533,19304781,35844032,15125259,19561787,11797096,10958632,8786082,23754746,9388406,16996702,17805568,11124539,16451623,2961259,11715041,19498035,15194483,12730726,18162838,11802391,12730723,19626646,33082508,15057823,12782124,28973544,9843980,15236766,15238507,18206218,29878108,9811942,16357227,25002992,26220404,29189765,12720574,34076875,33924158,1772410,31685878,30347474,22122342,28694852,8829631,11587075,10319852,30352401,32065983,16446308,10802640,12843442,30519487,12900898,27682995,9691180,23700380,32879135,36769704,8160743,34030490,11668390,15466702,11121012,10339753,26474913,24734784,36506301,19172181,14578904,10516430,12491623,17955261,22907505,21909369,18188004,33329716,31454785,21824424,30989085,32772048,17268172,29343559,31412249,24439386,17019649,10453734,15675355,22919075,15674730,26484295,19738379,26718406,29367313,33658376,12053204,11331904,10712109,25989982,14523423,36381038,14583745,10087301,7855259,15639127,3556034[uid]

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A nonimprinted Prader-Willi Syndrome (PWS)-region gene regulates a different chromosomal domain in trans but the imprinted pws loci do not alter genome-wide mRNA levels.

Stefan M, Portis T, Longnecker R, Nicholls RD. Stefan M, et al. Genomics. 2005 May;85(5):630-40. doi: 10.1016/j.ygeno.2005.02.004. Genomics. 2005. PMID: 15820315

Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes.

Stefan M, Claiborn KC, Stasiek E, Chai JH, Ohta T, Longnecker R, Greally JM, Nicholls RD. Stefan M, et al. BMC Genomics. 2005 Nov 9;6:157. doi: 10.1186/1471-2164-6-157. BMC Genomics. 2005. PMID: 16280085 Free PMC article.

Control elements within the PWS/AS imprinting box and their function in the imprinting process.

Kantor B, Makedonski K, Green-Finberg Y, Shemer R, Razin A. Kantor B, et al. Hum Mol Genet. 2004 Apr 1;13(7):751-62. doi: 10.1093/hmg/ddh085. Epub 2004 Feb 12. Hum Mol Genet. 2004. PMID: 14962980

The Prader-Willi syndrome murine imprinting center is not involved in the spatio-temporal transcriptional regulation of the Necdin gene.

Watrin F, Le Meur E, Roeckel N, Ripoche MA, Dandolo L, Muscatelli F. Watrin F, et al. BMC Genet. 2005 Jan 5;6:1. doi: 10.1186/1471-2156-6-1. BMC Genet. 2005. PMID: 15634360 Free PMC article.

The imprinting box of the Prader-Willi/Angelman syndrome domain.

Shemer R, Hershko AY, Perk J, Mostoslavsky R, Tsuberi B, Cedar H, Buiting K, Razin A. Shemer R, et al. Nat Genet. 2000 Dec;26(4):440-3. doi: 10.1038/82571. Nat Genet. 2000. PMID: 11101841

The mouse Necdin gene is expressed from the paternal allele only and lies in the 7C region of the mouse chromosome 7, a region of conserved synteny to the human Prader-Willi syndrome region.

Watrin F, Roëckel N, Lacroix L, Mignon C, Mattei MG, Disteche C, Muscatelli F. Watrin F, et al. Eur J Hum Genet. 1997 Sep-Oct;5(5):324-32. Eur J Hum Genet. 1997. PMID: 9412790

Exclusion of SNRPN as a major determinant of Prader-Willi syndrome by a translocation breakpoint.

Schulze A, Hansen C, Skakkebaek NE, Brøndum-Nielsen K, Ledbeter DH, Tommerup N. Schulze A, et al. Nat Genet. 1996 Apr;12(4):452-4. doi: 10.1038/ng0496-452. Nat Genet. 1996. PMID: 8630505

Small nuclear ribonucleoprotein polypeptide N (SNRPN), an expressed gene in the Prader-Willi syndrome critical region.

Ozçelik T, Leff S, Robinson W, Donlon T, Lalande M, Sanjines E, Schinzel A, Francke U. Ozçelik T, et al. Nat Genet. 1992 Dec;2(4):265-9. doi: 10.1038/ng1292-265. Nat Genet. 1992. PMID: 1303277

Paternal expression of a novel imprinted gene, Peg12/Frat3, in the mouse 7C region homologous to the Prader-Willi syndrome region.

Kobayashi S, Kohda T, Ichikawa H, Ogura A, Ohki M, Kaneko-Ishino T, Ishino F. Kobayashi S, et al. Biochem Biophys Res Commun. 2002 Jan 11;290(1):403-8. doi: 10.1006/bbrc.2001.6160. Biochem Biophys Res Commun. 2002. PMID: 11779183

Identification of novel imprinted transcripts in the Prader-Willi syndrome and Angelman syndrome deletion region: further evidence for regional imprinting control.

Lee S, Wevrick R. Lee S, et al. Am J Hum Genet. 2000 Mar;66(3):848-58. doi: 10.1086/302817. Am J Hum Genet. 2000. PMID: 10712201 Free PMC article.

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