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Results: 1 to 20 of 138

1.

Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer.

Young J, Barker MA, Simms LA, Walsh MD, Biden KG, Buchanan D, Buttenshaw R, Whitehall VL, Arnold S, Jackson L, Kambara T, Spring KJ, Jenkins MA, Walker GJ, Hopper JL, Leggett BA, Jass JR.

Clin Gastroenterol Hepatol. 2005 Mar;3(3):254-63.

PMID:
15765445
[PubMed - indexed for MEDLINE]
2.

BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum.

Kambara T, Simms LA, Whitehall VL, Spring KJ, Wynter CV, Walsh MD, Barker MA, Arnold S, McGivern A, Matsubara N, Tanaka N, Higuchi T, Young J, Jass JR, Leggett BA.

Gut. 2004 Aug;53(8):1137-44.

PMID:
15247181
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Detection of mismatch repair gene germline mutation carrier among Chinese population with colorectal cancer.

Jin HY, Liu X, Li VK, Ding Y, Yang B, Geng J, Lai R, Ding S, Ni M, Zhao R.

BMC Cancer. 2008 Feb 7;8:44. doi: 10.1186/1471-2407-8-44.

PMID:
18257912
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer.

Deng G, Bell I, Crawley S, Gum J, Terdiman JP, Allen BA, Truta B, Sleisenger MH, Kim YS.

Clin Cancer Res. 2004 Jan 1;10(1 Pt 1):191-5.

PMID:
14734469
[PubMed - indexed for MEDLINE]
Free Article
5.

BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?

Velho S, Moutinho C, Cirnes L, Albuquerque C, Hamelin R, Schmitt F, Carneiro F, Oliveira C, Seruca R.

BMC Cancer. 2008 Sep 9;8:255. doi: 10.1186/1471-2407-8-255.

PMID:
18782444
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Promoter hypermethylation frequency and BRAF mutations distinguish hereditary non-polyposis colon cancer from sporadic MSI-H colon cancer.

McGivern A, Wynter CV, Whitehall VL, Kambara T, Spring KJ, Walsh MD, Barker MA, Arnold S, Simms LA, Leggett BA, Young J, Jass JR.

Fam Cancer. 2004;3(2):101-7.

PMID:
15340260
[PubMed - indexed for MEDLINE]
7.

Analysis of somatic molecular changes, clinicopathological features, family history, and germline mutations in colorectal cancer families: evidence for efficient diagnosis of HNPCC and for the existence of distinct groups of non-HNPCC families.

Johnson V, Lipton LR, Cummings C, Eftekhar Sadat AT, Izatt L, Hodgson SV, Talbot IC, Thomas HJ, Silver AJ, Tomlinson IP.

J Med Genet. 2005 Oct;42(10):756-62. Epub 2005 Mar 23.

PMID:
15788729
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The case for a genetic predisposition to serrated neoplasia in the colorectum: hypothesis and review of the literature.

Young J, Jass JR.

Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):1778-84. Review.

PMID:
17035382
[PubMed - indexed for MEDLINE]
Free Article
9.

The profile of hMLH1 methylation and microsatellite instability in colorectal and non-small cell lung cancer.

Okuda T, Kawakami K, Ishiguro K, Oda M, Omura K, Watanabe G.

Int J Mol Med. 2005 Jan;15(1):85-90.

PMID:
15583832
[PubMed - indexed for MEDLINE]
10.

Clinicopathological features of CpG island methylator phenotype-positive colorectal cancer and its adverse prognosis in relation to KRAS/BRAF mutation.

Lee S, Cho NY, Choi M, Yoo EJ, Kim JH, Kang GH.

Pathol Int. 2008 Feb;58(2):104-13. doi: 10.1111/j.1440-1827.2007.02197.x.

PMID:
18199160
[PubMed - indexed for MEDLINE]
11.

Somatic BRAF-V600E mutations in familial colorectal cancer.

Vandrovcova J, Lagerstedt-Robinsson K, PĂ„hlman L, Lindblom A.

Cancer Epidemiol Biomarkers Prev. 2006 Nov;15(11):2270-3.

PMID:
17119056
[PubMed - indexed for MEDLINE]
Free Article
12.

The mechanism of microsatellite instability is different in synchronous and metachronous colorectal cancer.

Velayos FS, Lee SH, Qiu H, Dykes S, Yiu R, Terdiman JP, Garcia-Aguilar J.

J Gastrointest Surg. 2005 Mar;9(3):329-35.

PMID:
15749592
[PubMed - indexed for MEDLINE]
13.

Differential involvement of the hypermethylator phenotype in hereditary and sporadic colorectal cancers with high-frequency microsatellite instability.

Yamamoto H, Min Y, Itoh F, Imsumran A, Horiuchi S, Yoshida M, Iku S, Fukushima H, Imai K.

Genes Chromosomes Cancer. 2002 Mar;33(3):322-5.

PMID:
11807990
[PubMed - indexed for MEDLINE]
14.

Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis.

Minoo P, Moyer MP, Jass JR.

J Pathol. 2007 Jun;212(2):124-33.

PMID:
17427169
[PubMed - indexed for MEDLINE]
15.

BRAF mutation, CpG island methylator phenotype and microsatellite instability occur more frequently and concordantly in mucinous than non-mucinous colorectal cancer.

Tanaka H, Deng G, Matsuzaki K, Kakar S, Kim GE, Miura S, Sleisenger MH, Kim YS.

Int J Cancer. 2006 Jun 1;118(11):2765-71.

PMID:
16381005
[PubMed - indexed for MEDLINE]
16.

Frequency of familial colon cancer and hereditary nonpolyposis colorectal cancer (Lynch syndrome) in a large population database.

Kerber RA, Neklason DW, Samowitz WS, Burt RW.

Fam Cancer. 2005;4(3):239-44.

PMID:
16136384
[PubMed - indexed for MEDLINE]
17.

Association between methylation in mismatch repair genes, V600E BRAF mutation and microsatellite instability in colorectal cancer patients.

Rasuck CG, Leite SM, Komatsuzaki F, Ferreira AC, Oliveira VC, Gomes KB.

Mol Biol Rep. 2012 Mar;39(3):2553-60. doi: 10.1007/s11033-011-1007-8. Epub 2011 Jun 17.

PMID:
21681432
[PubMed - indexed for MEDLINE]
18.

Familial microsatellite-stable non-polyposis colorectal cancer: incidence and characteristics in a clinic-based population.

Rovella V, Carrara S, Crucitti SC, Coco C, Magistrelli P, Lucci-Cordisco E, Anti M, Neri G, Genuardi M.

Ann Oncol. 2001 Jun;12(6):813-8.

PMID:
11484957
[PubMed - indexed for MEDLINE]
Free Article
19.

Histologic features distinguish microsatellite-high from microsatellite-low and microsatellite-stable colorectal carcinomas, but do not differentiate germline mutations from methylation of the MLH1 promoter.

Yearsley M, Hampel H, Lehman A, Nakagawa H, de la Chapelle A, Frankel WL.

Hum Pathol. 2006 Jul;37(7):831-8. Epub 2006 May 19.

PMID:
16784982
[PubMed - indexed for MEDLINE]
20.

Hereditary nonpolyposis colorectal cancer: diagnostic strategies and their implications.

Bonis PA, Trikalinos TA, Chung M, Chew P, Ip S, DeVine DA, Lau J.

Evid Rep Technol Assess (Full Rep). 2007 May;(150):1-180. Review.

PMID:
17764220
[PubMed - indexed for MEDLINE]
Free Article

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