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Complement factor H polymorphism and age-related macular degeneration.

Edwards AO, Ritter R 3rd, Abel KJ, Manning A, Panhuysen C, Farrer LA.

Science. 2005 Apr 15;308(5720):421-4. Epub 2005 Mar 10.


Complement factor H variant increases the risk of age-related macular degeneration.

Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P, Spencer KL, Kwan SY, Noureddine M, Gilbert JR, Schnetz-Boutaud N, Agarwal A, Postel EA, Pericak-Vance MA.

Science. 2005 Apr 15;308(5720):419-21. Epub 2005 Mar 10.


Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration.

Schmidt S, Hauser MA, Scott WK, Postel EA, Agarwal A, Gallins P, Wong F, Chen YS, Spencer K, Schnetz-Boutaud N, Haines JL, Pericak-Vance MA.

Am J Hum Genet. 2006 May;78(5):852-64. Epub 2006 Mar 20.


Ethnic variation in AMD-associated complement factor H polymorphism p.Tyr402His.

Grassi MA, Fingert JH, Scheetz TE, Roos BR, Ritch R, West SK, Kawase K, Shire AM, Mullins RF, Stone EM.

Hum Mutat. 2006 Sep;27(9):921-5.


Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk.

Rivera A, Fisher SA, Fritsche LG, Keilhauer CN, Lichtner P, Meitinger T, Weber BH.

Hum Mol Genet. 2005 Nov 1;14(21):3227-36. Epub 2005 Sep 20.


Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration.

Kim IK, Ji F, Morrison MA, Adams S, Zhang Q, Lane AM, Capone A, Dryja TP, Ott J, Miller JW, DeAngelis MM.

Mol Vis. 2008 Aug 11;14:1487-95.


Association of complement factor H Y402H gene polymorphism with different subtypes of exudative age-related macular degeneration.

Wegscheider BJ, Weger M, Renner W, Steinbrugger I, März W, Mossböck G, Temmel W, El-Shabrawi Y, Schmut O, Jahrbacher R, Haas A.

Ophthalmology. 2007 Apr;114(4):738-42.


Association of complement factor H polymorphisms with exudative age-related macular degeneration.

Chen LJ, Liu DT, Tam PO, Chan WM, Liu K, Chong KK, Lam DS, Pang CP.

Mol Vis. 2006 Dec 5;12:1536-42.


Association between complement factor H gene polymorphisms and neovascular age-related macular degeneration in Koreans.

Kim NR, Kang JH, Kwon OW, Lee SJ, Oh JH, Chin HS.

Invest Ophthalmol Vis Sci. 2008 May;49(5):2071-6. doi: 10.1167/iovs.07-1195. Epub 2008 Jan 25.


Almost total protection from age-related macular degeneration by haplotypes of the Regulators of Complement Activation.

Williamson JF, McLure CA, Guymer RH, Baird PN, Millman J, Cantsilieris S, Dawkins RL.

Genomics. 2011 Dec;98(6):412-21. doi: 10.1016/j.ygeno.2011.08.002. Epub 2011 Aug 9.


Complement factor H polymorphism in age-related macular degeneration.

Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferris FL, Ott J, Barnstable C, Hoh J.

Science. 2005 Apr 15;308(5720):385-9. Epub 2005 Mar 10.


Protective effect of complement factor B and complement component 2 variants in age-related macular degeneration.

Spencer KL, Hauser MA, Olson LM, Schmidt S, Scott WK, Gallins P, Agarwal A, Postel EA, Pericak-Vance MA, Haines JL.

Hum Mol Genet. 2007 Aug 15;16(16):1986-92. Epub 2007 Jun 18.


Correlation of complement factor H gene polymorphisms with exudative age-related macular degeneration in a Chinese cohort.

Dong L, Qu Y, Jiang H, Dai H, Zhou F, Xu X, Bi H, Pan X, Dang G.

Neurosci Lett. 2011 Jan 25;488(3):283-7. doi: 10.1016/j.neulet.2010.11.048. Epub 2010 Nov 24.


Association of the Y402H polymorphism in complement factor H gene and neovascular age-related macular degeneration in Chinese patients.

Lau LI, Chen SJ, Cheng CY, Yen MY, Lee FL, Lin MW, Hsu WM, Wei YH.

Invest Ophthalmol Vis Sci. 2006 Aug;47(8):3242-6.


Complement factor H polymorphism in age-related macular degeneration.

Narayanan R, Butani V, Boyer DS, Atilano SR, Resende GP, Kim DS, Chakrabarti S, Kuppermann BD, Khatibi N, Chwa M, Nesburn AB, Kenney MC.

Ophthalmology. 2007 Jul;114(7):1327-31. Epub 2007 Feb 16.


Systematic review and meta-analysis of the association between complement factor H Y402H polymorphisms and age-related macular degeneration.

Thakkinstian A, Han P, McEvoy M, Smith W, Hoh J, Magnusson K, Zhang K, Attia J.

Hum Mol Genet. 2006 Sep 15;15(18):2784-90. Epub 2006 Aug 11. Review.


Complement factor H polymorphisms in Japanese population with age-related macular degeneration.

Okamoto H, Umeda S, Obazawa M, Minami M, Noda T, Mizota A, Honda M, Tanaka M, Koyama R, Takagi I, Sakamoto Y, Saito Y, Miyake Y, Iwata T.

Mol Vis. 2006 Mar 6;12:156-8.


Analysis of CFH, TLR4, and APOE polymorphism in India suggests the Tyr402His variant of CFH to be a global marker for age-related macular degeneration.

Kaur I, Hussain A, Hussain N, Das T, Pathangay A, Mathai A, Hussain A, Nutheti R, Nirmalan PK, Chakrabarti S.

Invest Ophthalmol Vis Sci. 2006 Sep;47(9):3729-35.


HTRA1 promoter polymorphism predisposes Japanese to age-related macular degeneration.

Yoshida T, DeWan A, Zhang H, Sakamoto R, Okamoto H, Minami M, Obazawa M, Mizota A, Tanaka M, Saito Y, Takagi I, Hoh J, Iwata T.

Mol Vis. 2007 Apr 4;13:545-8.

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