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Results: 1 to 20 of 108

1.

Activated protein C inhibits local coagulation after intrapulmonary delivery of endotoxin in humans.

van der Poll T, Levi M, Nick JA, Abraham E.

Am J Respir Crit Care Med. 2005 May 15;171(10):1125-8. Epub 2005 Mar 4.

PMID:
15750041
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Effects of activated protein C on coagulation and fibrinolysis in rabbits with endotoxin induced acute lung injury.

He HY, Wang C, Pang BS.

Chin Med J (Engl). 2008 Dec 20;121(24):2561-5.

PMID:
19187596
[PubMed - indexed for MEDLINE]
Free Article
3.

Salmeterol enhances pulmonary fibrinolysis in healthy volunteers.

Maris NA, de Vos AF, Bresser P, van der Zee JS, Jansen HM, Levi M, van der Poll T.

Crit Care Med. 2007 Jan;35(1):57-63.

PMID:
17080003
[PubMed - indexed for MEDLINE]
4.

Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats.

Choi G, Hofstra JJ, Roelofs JJ, Florquin S, Bresser P, Levi M, van der Poll T, Schultz MJ.

Crit Care Med. 2007 May;35(5):1362-8.

PMID:
17414732
[PubMed - indexed for MEDLINE]
5.

Activation of coagulation and inhibition of fibrinolysis in the human lung on bronchial instillation of lipoteichoic acid and lipopolysaccharide.

Hoogerwerf JJ, de Vos AF, Levi M, Bresser P, van der Zee JS, Draing C, von Aulock S, van der Poll T.

Crit Care Med. 2009 Feb;37(2):619-25. doi: 10.1097/CCM.0b013e31819584f9.

PMID:
19114879
[PubMed - indexed for MEDLINE]
6.

Peritoneal lavage with activated protein C alters compartmentalized coagulation and fibrinolysis and improves survival in polymicrobial peritonitis.

van Veen SQ, Levi M, van Vliet AK, Florquin S, van Gulik TM, Boermeester MA.

Crit Care Med. 2006 Nov;34(11):2799-805.

PMID:
17006359
[PubMed - indexed for MEDLINE]
7.

Intravenous administration of activated protein C in Pseudomonas-induced lung injury: impact on lung fluid balance and the inflammatory response.

Robriquet L, Collet F, Tournoys A, Prangère T, Nevière R, Fourrier F, Guery BP.

Respir Res. 2006 Mar 22;7:41.

PMID:
16553944
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Recombinant activated protein C attenuates coagulopathy and inflammation when administered early in murine pneumococcal pneumonia.

Schouten M, van 't Veer C, Roelofs JJ, Gerlitz B, Grinnell BW, Levi M, van der Poll T.

Thromb Haemost. 2011 Dec;106(6):1189-96. doi: 10.1160/TH11-06-0438. Epub 2011 Sep 8.

PMID:
21901240
[PubMed - indexed for MEDLINE]
9.

Recombinant human activated protein C (rhAPC; drotrecogin alfa [activated]) has minimal effect on markers of coagulation, fibrinolysis, and inflammation in acute human endotoxemia.

Derhaschnig U, Reiter R, Knöbl P, Baumgartner M, Keen P, Jilma B.

Blood. 2003 Sep 15;102(6):2093-8. Epub 2003 May 15.

PMID:
12750166
[PubMed - indexed for MEDLINE]
Free Article
10.

Activation of coagulation and inhibition of fibrinolysis in the lung after inhalation of lipopolysaccharide by healthy volunteers.

Maris NA, de Vos AF, Bresser P, van der Zee JS, Meijers JC, Lijnen HR, Levi M, Jansen HM, van der Poll T.

Thromb Haemost. 2005 Jun;93(6):1036-40.

PMID:
15968385
[PubMed - indexed for MEDLINE]
11.

Intratracheal administration of activated protein C inhibits bleomycin-induced lung fibrosis in the mouse.

Yasui H, Gabazza EC, Tamaki S, Kobayashi T, Hataji O, Yuda H, Shimizu S, Suzuki K, Adachi Y, Taguchi O.

Am J Respir Crit Care Med. 2001 Jun;163(7):1660-8.

PMID:
11401891
[PubMed - indexed for MEDLINE]
12.

The effects of supra-normal protein C levels on markers of coagulation, fibrinolysis and inflammation in a human model of endotoxemia.

Spiel AO, Firbas C, Mayr FB, Leitner JM, Schmidt B, Knöbl P, Varadi K, Jilma B.

Thromb Haemost. 2005 Dec;94(6):1148-55.

PMID:
16411386
[PubMed - indexed for MEDLINE]
13.

Activated protein C ameliorates coagulopathy but does not influence outcome in lethal H1N1 influenza: a controlled laboratory study.

Schouten M, Sluijs KF, Gerlitz B, Grinnell BW, Roelofs JJ, Levi MM, van 't Veer C, van der Poll T.

Crit Care. 2010;14(2):R65. doi: 10.1186/cc8964. Epub 2010 Apr 14.

PMID:
20398279
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Natural anticoagulants limit lipopolysaccharide-induced pulmonary coagulation but not inflammation.

Choi G, Vlaar AP, Schouten M, Van't Veer C, van der Poll T, Levi M, Schultz MJ.

Eur Respir J. 2007 Sep;30(3):423-8. Epub 2007 May 30.

PMID:
17537762
[PubMed - indexed for MEDLINE]
Free Article
15.

Effects of intra-abdominal administration of recombinant tissue plasminogen activator on coagulation, fibrinolysis and inflammatory responses in experimental polymicrobial peritonitis.

van Veen SQ, Meijers JC, Levi M, van Gulik TM, Boermeester MA.

Shock. 2007 May;27(5):534-41.

PMID:
17438459
[PubMed - indexed for MEDLINE]
16.

Transfusion-related acute lung injury in cardiac surgery patients is characterized by pulmonary inflammation and coagulopathy: a prospective nested case-control study.

Vlaar AP, Hofstra JJ, Determann RM, Veelo DP, Paulus F, Levi M, Zeerleder S, Vroom MB, Schultz MJ, Juffermans NP.

Crit Care Med. 2012 Oct;40(10):2813-20.

PMID:
22824931
[PubMed - indexed for MEDLINE]
17.

Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats.

Choi G, Hofstra JJ, Roelofs JJ, Rijneveld AW, Bresser P, van der Zee JS, Florquin S, van der Poll T, Levi M, Schultz MJ.

Crit Care Med. 2008 Jan;36(1):204-10.

PMID:
18090375
[PubMed - indexed for MEDLINE]
18.

[Effect of inhalation of aerosolized unfractioned heparin on peri alveolar coagulability and inflammatory response in endotoxin induced acute lung injury rat model].

Wang ZY, Yang BX, Zhu X, Wu SN.

Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2011 Apr;23(4):239-42. Chinese.

PMID:
21473829
[PubMed - indexed for MEDLINE]
Free Article
19.

Differential effects of anti-cytokine treatment on bronchoalveolar hemostasis in endotoxemic chimpanzees.

Levi M, van Der POLL T, ten CATE H, Kuipers B, Biemond BJ, Jansen HM, ten CATE JW.

Am J Respir Crit Care Med. 1998 Jul;158(1):92-8.

PMID:
9655712
[PubMed - indexed for MEDLINE]
20.

Inhaled unfractionated heparin improves abnormalities of alveolar coagulation, fibrinolysis and inflammation in endotoxemia-induced lung injury rats.

Wang ZY, Wu SN, Zhu ZZ, Yang BX, Zhu X.

Chin Med J (Engl). 2013 Jan;126(2):318-24.

PMID:
23324284
[PubMed - indexed for MEDLINE]
Free Article

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