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Results: 1 to 20 of 283

1.

Replicon cell culture system as a valuable tool in antiviral drug discovery against hepatitis C virus.

Horscroft N, Lai VC, Cheney W, Yao N, Wu JZ, Hong Z, Zhong W.

Antivir Chem Chemother. 2005;16(1):1-12. Review.

PMID:
15739617
[PubMed - indexed for MEDLINE]
2.

Evaluation systems for anti-HCV drugs.

Moriishi K, Matsuura Y.

Adv Drug Deliv Rev. 2007 Oct 10;59(12):1213-21. Epub 2007 Aug 9. Review.

PMID:
17720275
[PubMed - indexed for MEDLINE]
3.

2'-deoxy-4'-azido nucleoside analogs are highly potent inhibitors of hepatitis C virus replication despite the lack of 2'-alpha-hydroxyl groups.

Klumpp K, Kalayanov G, Ma H, Le Pogam S, Leveque V, Jiang WR, Inocencio N, De Witte A, Rajyaguru S, Tai E, Chanda S, Irwin MR, Sund C, Winqist A, Maltseva T, Eriksson S, Usova E, Smith M, Alker A, Najera I, Cammack N, Martin JA, Johansson NG, Smith DB.

J Biol Chem. 2008 Jan 25;283(4):2167-75. Epub 2007 Nov 14.

PMID:
18003608
[PubMed - indexed for MEDLINE]
Free Article
4.

Selective inhibitors of hepatitis C virus replication.

Neyts J.

Antiviral Res. 2006 Sep;71(2-3):363-71. Epub 2006 Jun 23. Review.

PMID:
16843538
[PubMed - indexed for MEDLINE]
5.

Recent advances in discovery and development of promising therapeutics against hepatitis C virus NS5B RNA-dependent RNA polymerase.

Wu JZ, Yao N, Walker M, Hong Z.

Mini Rev Med Chem. 2005 Dec;5(12):1103-12. Review.

PMID:
16375756
[PubMed - indexed for MEDLINE]
6.

Hepatitis C virus cell culture replication systems: their potential use for the development of antiviral therapies.

Randall G, Rice CM.

Curr Opin Infect Dis. 2001 Dec;14(6):743-7. Review.

PMID:
11964894
[PubMed - indexed for MEDLINE]
7.

High-throughput screening of HCV RNA replication inhibitors by means of a reporter replicon system.

Hao W, Duggal R.

Methods Mol Biol. 2009;510:243-50. doi: 10.1007/978-1-59745-394-3_18.

PMID:
19009266
[PubMed - indexed for MEDLINE]
8.

Discovery and characterization of substituted diphenyl heterocyclic compounds as potent and selective inhibitors of hepatitis C virus replication.

Huang P, Goff DA, Huang Q, Martinez A, Xu X, Crowder S, Issakani SD, Anderson E, Sheng N, Achacoso P, Yen A, Kinsella T, Darwish IS, Kolluri R, Hong H, Qu K, Stauffer E, Goldstein E, Singh R, Payan DG, Lu HH.

Antimicrob Agents Chemother. 2008 Apr;52(4):1419-29. doi: 10.1128/AAC.00525-07. Epub 2008 Jan 28.

PMID:
18227176
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Nucleoside analog inhibitors of hepatitis C virus replication.

Carroll SS, Olsen DB.

Infect Disord Drug Targets. 2006 Mar;6(1):17-29. Review.

PMID:
16787301
[PubMed - indexed for MEDLINE]
10.

A cell-based, high-throughput screen for small molecule regulators of hepatitis C virus replication.

Kim SS, Peng LF, Lin W, Choe WH, Sakamoto N, Kato N, Ikeda M, Schreiber SL, Chung RT.

Gastroenterology. 2007 Jan;132(1):311-20. Epub 2006 Oct 21. Erratum in: Gastroenterology. 2007 Aug;133(2):730. Gastroenterology. 2007 May;132(5):2082. Gastroenterology. 2007 Mar;132(3):1208. Kato, Nobuyuki [added]; Ikeda, Masanori [added].

PMID:
17241881
[PubMed - indexed for MEDLINE]
11.

Non-nucleoside inhibitors of the HCV polymerase.

Sarisky RT.

J Antimicrob Chemother. 2004 Jul;54(1):14-6. Epub 2004 Jun 9. Review.

PMID:
15190019
[PubMed - indexed for MEDLINE]
Free Article
12.

Modulation of host metabolism as a target of new antivirals.

Ikeda M, Kato N.

Adv Drug Deliv Rev. 2007 Oct 10;59(12):1277-89. Epub 2007 Aug 11. Review.

PMID:
17897752
[PubMed - indexed for MEDLINE]
13.

Silibinin and related compounds are direct inhibitors of hepatitis C virus RNA-dependent RNA polymerase.

Ahmed-Belkacem A, Ahnou N, Barbotte L, Wychowski C, Pallier C, Brillet R, Pohl RT, Pawlotsky JM.

Gastroenterology. 2010 Mar;138(3):1112-22. doi: 10.1053/j.gastro.2009.11.053. Epub 2009 Dec 4.

PMID:
19962982
[PubMed - indexed for MEDLINE]
14.

[Current approaches for developing new anti-HCV agents and analyses of HCV replication using anti-HCV agents].

Watashi K, Shimotohno K.

Uirusu. 2005 Jun;55(1):105-10. Review. Japanese.

PMID:
16308536
[PubMed - indexed for MEDLINE]
Free Article
15.

In vitro replication models for the hepatitis C virus.

Sheehy P, Mullan B, Moreau I, Kenny-Walsh E, Shanahan F, Scallan M, Fanning LJ.

J Viral Hepat. 2007 Jan;14(1):2-10. Review.

PMID:
17212638
[PubMed - indexed for MEDLINE]
16.

Antiviral action of interferon-alpha against hepatitis C virus replicon and its modulation by interferon-gamma and interleukin-8.

Jia Y, Wei L, Jiang D, Wang J, Cong X, Fei R.

J Gastroenterol Hepatol. 2007 Aug;22(8):1278-85. Epub 2007 Jun 12.

PMID:
17565587
[PubMed - indexed for MEDLINE]
17.

In vitro resistance study of AG-021541, a novel nonnucleoside inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.

Shi ST, Herlihy KJ, Graham JP, Fuhrman SA, Doan C, Parge H, Hickey M, Gao J, Yu X, Chau F, Gonzalez J, Li H, Lewis C, Patick AK, Duggal R.

Antimicrob Agents Chemother. 2008 Feb;52(2):675-83. Epub 2007 Dec 10.

PMID:
18070954
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

HCV research and anti-HCV drug discovery: toward the next generation.

Wakita T.

Adv Drug Deliv Rev. 2007 Oct 10;59(12):1196-9. Epub 2007 Aug 25.

PMID:
17905463
[PubMed - indexed for MEDLINE]
19.

Advances in hepatitis C: what is coming in the next 5 years?

Locarnini SA, Bartholomeusz A.

J Gastroenterol Hepatol. 2002 Apr;17(4):442-7. Review.

PMID:
11982725
[PubMed - indexed for MEDLINE]
20.

The novel nucleoside analog R1479 (4'-azidocytidine) is a potent inhibitor of NS5B-dependent RNA synthesis and hepatitis C virus replication in cell culture.

Klumpp K, Lévêque V, Le Pogam S, Ma H, Jiang WR, Kang H, Granycome C, Singer M, Laxton C, Hang JQ, Sarma K, Smith DB, Heindl D, Hobbs CJ, Merrett JH, Symons J, Cammack N, Martin JA, Devos R, Nájera I.

J Biol Chem. 2006 Feb 17;281(7):3793-9. Epub 2005 Nov 29.

PMID:
16316989
[PubMed - indexed for MEDLINE]
Free Article

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