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Results: 1 to 20 of 440

1.

Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteins.

Hu J, Hubbard SR.

J Biol Chem. 2005 May 13;280(19):18943-9. Epub 2005 Feb 28.

PMID:
15737992
[PubMed - indexed for MEDLINE]
Free Article
2.

A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation.

Peschard P, Ishiyama N, Lin T, Lipkowitz S, Park M.

J Biol Chem. 2004 Jul 9;279(28):29565-71. Epub 2004 Apr 29.

PMID:
15123609
[PubMed - indexed for MEDLINE]
Free Article
3.

Asb6, an adipocyte-specific ankyrin and SOCS box protein, interacts with APS to enable recruitment of elongins B and C to the insulin receptor signaling complex.

Wilcox A, Katsanakis KD, Bheda F, Pillay TS.

J Biol Chem. 2004 Sep 10;279(37):38881-8. Epub 2004 Jul 1.

PMID:
15231829
[PubMed - indexed for MEDLINE]
Free Article
4.

Structural basis for phosphotyrosine recognition by the Src homology-2 domains of the adapter proteins SH2-B and APS.

Hu J, Hubbard SR.

J Mol Biol. 2006 Aug 4;361(1):69-79. Epub 2006 Jun 16.

PMID:
16824542
[PubMed - indexed for MEDLINE]
5.

Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.

van der Geer P, Wiley S, Gish GD, Lai VK, Stephens R, White MF, Kaplan D, Pawson T.

Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):963-8.

PMID:
8577769
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.

Hu J, Liu J, Ghirlando R, Saltiel AR, Hubbard SR.

Mol Cell. 2003 Dec;12(6):1379-89.

PMID:
14690593
[PubMed - indexed for MEDLINE]
Free Article
8.

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase.

Meng W, Sawasdikosol S, Burakoff SJ, Eck MJ.

Nature. 1999 Mar 4;398(6722):84-90.

PMID:
10078535
[PubMed - indexed for MEDLINE]
9.

Additional serine/threonine phosphorylation reduces binding affinity but preserves interface topography of substrate proteins to the c-Cbl TKB domain.

Sun Q, Jackson RA, Ng C, Guy GR, Sivaraman J.

PLoS One. 2010 Sep 22;5(9):e12819. doi: 10.1371/journal.pone.0012819.

PMID:
20877636
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Functional effects of APS and SH2-B on insulin receptor signalling.

Ahmed Z, Pillay TS.

Biochem Soc Trans. 2001 Aug;29(Pt 4):529-34. Review.

PMID:
11498022
[PubMed - indexed for MEDLINE]
11.

Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.

Calderwood DA, Fujioka Y, de Pereda JM, GarcĂ­a-Alvarez B, Nakamoto T, Margolis B, McGlade CJ, Liddington RC, Ginsberg MH.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2272-7. Epub 2003 Feb 26.

PMID:
12606711
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Ubiquitin ligase activity of c-Cbl guides the epidermal growth factor receptor into clathrin-coated pits by two distinct modes of Eps15 recruitment.

de Melker AA, van der Horst G, Borst J.

J Biol Chem. 2004 Dec 31;279(53):55465-73. Epub 2004 Oct 1.

PMID:
15465819
[PubMed - indexed for MEDLINE]
Free Article
13.
14.

Mutational investigation of the specificity determining region of the Src SH2 domain.

Bradshaw JM, Mitaxov V, Waksman G.

J Mol Biol. 2000 Jun 2;299(2):521-35.

PMID:
10860756
[PubMed - indexed for MEDLINE]
15.

Dissection of the energetic coupling across the Src SH2 domain-tyrosyl phosphopeptide interface.

Lubman OY, Waksman G.

J Mol Biol. 2002 Feb 15;316(2):291-304.

PMID:
11851339
[PubMed - indexed for MEDLINE]
16.

C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus.

Wilhelmsen K, Burkhalter S, van der Geer P.

Oncogene. 2002 Feb 7;21(7):1079-89.

PMID:
11850825
[PubMed - indexed for MEDLINE]
Free Article
18.

Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket.

Villa F, Deak M, Bloomberg GB, Alessi DR, van Aalten DM.

J Biol Chem. 2005 Mar 4;280(9):8180-7. Epub 2004 Dec 20.

PMID:
15611135
[PubMed - indexed for MEDLINE]
Free Article
19.

Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A.

Li SC, Gish G, Yang D, Coffey AJ, Forman-Kay JD, Ernberg I, Kay LE, Pawson T.

Curr Biol. 1999 Dec 2;9(23):1355-62.

PMID:
10607564
[PubMed - indexed for MEDLINE]
Free Article
20.

A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the phosphotyrosine binding domain of insulin receptor substrate-1: an essential interaction for transformation.

Lannon CL, Martin MJ, Tognon CE, Jin W, Kim SJ, Sorensen PH.

J Biol Chem. 2004 Feb 20;279(8):6225-34. Epub 2003 Dec 9.

PMID:
14668342
[PubMed - indexed for MEDLINE]
Free Article

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