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Results: 1 to 20 of 151

1.

Effects of co-medicated drugs on cyclophosphamide bioactivation in human liver microsomes.

de Jonge ME, Huitema AD, van Dam SM, Rodenhuis S, Beijnen JH.

Anticancer Drugs. 2005 Mar;16(3):331-6.

PMID:
15711186
[PubMed - indexed for MEDLINE]
2.

Influence of co-medicated drugs on the biotransformation of thioTEPA to TEPA and thioTEPA-mercapturate.

van Maanen MJ, Huitema AD, Beijen JH.

Anticancer Res. 2000 May-Jun;20(3A):1711-6.

PMID:
10928097
[PubMed - indexed for MEDLINE]
3.

Cyclophosphamide and 4-Hydroxycyclophosphamide/aldophosphamide kinetics in patients receiving high-dose cyclophosphamide chemotherapy.

Anderson LW, Chen TL, Colvin OM, Grochow LB, Collins JM, Kennedy MJ, Strong JM.

Clin Cancer Res. 1996 Sep;2(9):1481-7.

PMID:
9816324
[PubMed - indexed for MEDLINE]
Free Article
4.

Aprepitant inhibits cyclophosphamide bioactivation and thiotepa metabolism.

de Jonge ME, Huitema AD, Holtkamp MJ, van Dam SM, Beijnen JH, Rodenhuis S.

Cancer Chemother Pharmacol. 2005 Oct;56(4):370-8. Epub 2005 Apr 19.

PMID:
15838656
[PubMed - indexed for MEDLINE]
5.
6.

The influence of interferon-alpha on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite in patients with multiple myeloma.

Hassan M, Nilsson C, Olsson H, Lundin J, Osterborg A.

Eur J Haematol. 1999 Sep;63(3):163-70.

PMID:
10485271
[PubMed - indexed for MEDLINE]
7.

Reduction of cyclophosphamide bioactivation by thioTEPA: critical sequence-dependency in high-dose chemotherapy regimens.

Huitema AD, Kerbusch T, Tibben MM, Rodenhuis S, Beijnen JH.

Cancer Chemother Pharmacol. 2000;46(2):119-27.

PMID:
10972481
[PubMed - indexed for MEDLINE]
8.

The effect of fluconazole on cyclophosphamide metabolism in children.

Yule SM, Walker D, Cole M, McSorley L, Cholerton S, Daly AK, Pearson AD, Boddy AV.

Drug Metab Dispos. 1999 Mar;27(3):417-21.

PMID:
10064575
[PubMed - indexed for MEDLINE]
Free Article
9.

A mechanism-based pharmacokinetic model for the cytochrome P450 drug-drug interaction between cyclophosphamide and thioTEPA and the autoinduction of cyclophosphamide.

Huitema AD, Mathôt RA, Tibben MM, Rodenhuis S, Beijnen JH.

J Pharmacokinet Pharmacodyn. 2001 Jun;28(3):211-30.

PMID:
11468938
[PubMed - indexed for MEDLINE]
10.

Integrated Population Pharmacokinetic Model of both cyclophosphamide and thiotepa suggesting a mutual drug-drug interaction.

de Jonge ME, Huitema AD, Rodenhuis S, Beijnen JH.

J Pharmacokinet Pharmacodyn. 2004 Apr;31(2):135-56.

PMID:
15379382
[PubMed - indexed for MEDLINE]
11.

Characterization of the cytochrome P450 involved in side-chain oxidation of cyclophosphamide in humans.

Bohnenstengel F, Hofmann U, Eichelbaum M, Kroemer HK.

Eur J Clin Pharmacol. 1996;51(3-4):297-301.

PMID:
9010702
[PubMed - indexed for MEDLINE]
12.

Effect of antifungal drugs on cytochrome P450 (CYP) 2C9, CYP2C19, and CYP3A4 activities in human liver microsomes.

Niwa T, Shiraga T, Takagi A.

Biol Pharm Bull. 2005 Sep;28(9):1805-8.

PMID:
16141567
[PubMed - indexed for MEDLINE]
Free Article
13.

Chemically stable N-methyl-4-(alkylthio)cyclophosphamide derivatives as prodrugs of 4-hydroxycyclophosphamide.

Moon KY, Shirota FN, Baturay N, Kwon CH.

J Med Chem. 1995 Mar 3;38(5):848-51.

PMID:
7877150
[PubMed - indexed for MEDLINE]
14.

Pharmacokinetics of cyclophosphamide and thiotepa in a conventional fractionated high-dose regimen compared with a novel simplified unfractionated regimen.

Ekhart C, Rodenhuis S, Beijnen JH, Huitema AD.

Ther Drug Monit. 2009 Feb;31(1):95-103. doi: 10.1097/FTD.0b013e318194e484.

PMID:
19155964
[PubMed - indexed for MEDLINE]
15.

Metabolic drug interactions between angiogenic inhibitor, TNP-470 and anticancer agents in primary cultured hepatocytes and microsomes.

Placidi L, Scott EC, Eckoff D, Bynon S, Sommadossi JP.

Drug Metab Dispos. 1999 May;27(5):623-6.

PMID:
10220492
[PubMed - indexed for MEDLINE]
Free Article
16.

Effects of paclitaxel, cyclophosphamide, ifosfamide, tamoxifen and cyclosporine on the metabolism of methoxymorpholinodoxorubicin in human liver microsomes.

Beulz-Riché D, Robert J, Riché C, Ratanasavanh D.

Cancer Chemother Pharmacol. 2002 Apr;49(4):274-80. Epub 2002 Jan 30.

PMID:
11914905
[PubMed - indexed for MEDLINE]
17.

Toxicity testing in vitro. II. Use of a microsome - cultured human fibroblast system to study the cytotoxicity of cyclophosphamide.

Cooper JT, Goldstein S.

Can J Physiol Pharmacol. 1976 Aug;54(4):546-50.

PMID:
974882
[PubMed - indexed for MEDLINE]
18.

Effect of antifungal drugs on cytochrome P450 (CYP) 1A2, CYP2D6, and CYP2E1 activities in human liver microsomes.

Niwa T, Inoue-Yamamoto S, Shiraga T, Takagi A.

Biol Pharm Bull. 2005 Sep;28(9):1813-6.

PMID:
16141569
[PubMed - indexed for MEDLINE]
Free Article
19.

Sparse sampling design for therapeutic drug monitoring of sequentially administered cyclophosphamide, thiotepa, and carboplatin (CTC).

de Jonge ME, Huitema AD, Rodenhuis S, Beijnen JH.

Ther Drug Monit. 2005 Jun;27(3):393-402.

PMID:
15905813
[PubMed - indexed for MEDLINE]
20.

[Drug-drug interaction of antifungal drugs].

Niwa T, Shiraga T, Takagi A.

Yakugaku Zasshi. 2005 Oct;125(10):795-805. Review. Japanese.

PMID:
16205037
[PubMed - indexed for MEDLINE]
Free Article

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