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Items: 1 to 20 of 55

1.

Flavopiridol reduces malignant transformation of the esophageal mucosa in p27 knockout mice.

Lechpammer M, Xu X, Ellis FH, Bhattacharaya N, Shapiro GI, Loda M.

Oncogene. 2005 Mar 3;24(10):1683-8.

PMID:
15674336
2.

Malignant transformation of the esophageal mucosa is enhanced in p27 knockout mice.

Ellis FH Jr, Xu X, Kulke MH, LoCicero J 3rd, Loda M.

J Thorac Cardiovasc Surg. 2001 Oct;122(4):809-14.

3.

Improvement of esophageal adenocarcinoma cell and xenograft responses to radiation by targeting cyclin-dependent kinases.

Raju U, Ariga H, Koto M, Lu X, Pickett J, Valdecanas D, Mason KA, Milas L.

Radiother Oncol. 2006 Aug;80(2):185-91. Epub 2006 Aug 14.

PMID:
16905211
4.

p27 and Barrett's esophagus: a review*.

Ellis FH Jr, Loda M.

Dis Esophagus. 2004;17(2):113-7. Review.

PMID:
15230722
5.

Rhabdoid tumor growth is inhibited by flavopiridol.

Smith ME, Cimica V, Chinni S, Challagulla K, Mani S, Kalpana GV.

Clin Cancer Res. 2008 Jan 15;14(2):523-32. doi: 10.1158/1078-0432.CCR-07-1347.

6.

Induction of apoptosis and down regulation of cell cycle proteins in mantle cell lymphoma by flavopiridol treatment.

Venkataraman G, Maududi T, Ozpuyan F, Bahar HI, Izban KF, Qin JZ, Alkan S.

Leuk Res. 2006 Nov;30(11):1377-84. Epub 2006 Apr 19.

PMID:
16624404
7.

Distinct roles for p53, p27Kip1, and p21Cip1 during tumor development.

Philipp-Staheli J, Kim KH, Liggitt D, Gurley KE, Longton G, Kemp CJ.

Oncogene. 2004 Jan 29;23(4):905-13.

PMID:
14647411
8.

Down-regulation of Cdk inhibitor p27 in oral squamous cell carcinoma.

Kudo Y, Kitajima S, Ogawa I, Miyauchi M, Takata T.

Oral Oncol. 2005 Feb;41(2):105-16. Review.

PMID:
15695111
9.

Immunohistochemical evaluation of pRb2/p130, VEGF, EZH2, p53, p16, p21waf-1, p27, and PCNA in Barrett's esophagus.

Merola E, Mattioli E, Minimo C, Zuo W, Rabitti C, Cicala M, Caviglia R, Pollice L, Gabbrielli A, Giordano A, Claudio PP.

J Cell Physiol. 2006 May;207(2):512-9.

PMID:
16447267
10.

Flavopiridol as a radio-sensitizer for esophageal cancer cell lines.

Sato S, Kajiyama Y, Sugano M, Iwanuma Y, Tsurumaru M.

Dis Esophagus. 2004;17(4):338-44.

PMID:
15569374
12.

Flavopiridol enhances human tumor cell radiosensitivity and prolongs expression of gammaH2AX foci.

Camphausen K, Brady KJ, Burgan WE, Cerra MA, Russell JS, Bull EE, Tofilon PJ.

Mol Cancer Ther. 2004 Apr;3(4):409-16.

13.

Cyclins and CDKS in development and cancer: lessons from genetically modified mice.

Santamaria D, Ortega S.

Front Biosci. 2006 Jan 1;11:1164-88. Review.

PMID:
16146805
14.

Alvocidib (Flavopiridol) suppresses tumor growth in SCID mice with human esophageal cancer xenografts without inducing apoptosis.

Sato S, Kajiyama Y, Sugano M, Iwanuma Y, Sonoue H, Matsumoto T, Tsurumaru M.

Surg Oncol. 2006 Aug;15(2):107-13. Epub 2006 Nov 13.

PMID:
17097874
15.

[Therapeutic effect of flavopiridol, a small molecular cyclin-dependent kinase inhibitor, in human ovarian carcinoma].

Song Y, Shen K, Tang PP.

Zhonghua Fu Chan Ke Za Zhi. 2007 Nov;42(11):761-4. Chinese.

PMID:
18307904
17.

The effect of the cyclin-dependent kinase inhibitor flavopiridol on anaplastic large cell lymphoma cells and relationship with NPM-ALK kinase expression and activity.

Bonvini P, Zorzi E, Mussolin L, Monaco G, Pigazzi M, Basso G, Rosolen A.

Haematologica. 2009 Jul;94(7):944-55. doi: 10.3324/haematol.2008.004861. Epub 2009 Jun 16.

18.
19.

Anti-tumor potential of 15,16-dihydrotanshinone I against breast adenocarcinoma through inducing G1 arrest and apoptosis.

Tsai SL, Suk FM, Wang CI, Liu DZ, Hou WC, Lin PJ, Hung LF, Liang YC.

Biochem Pharmacol. 2007 Dec 3;74(11):1575-86. Epub 2007 Aug 11.

PMID:
17869226
20.

Mutually exclusive cyclin-dependent kinase 4/cyclin D1 and cyclin-dependent kinase 6/cyclin D2 pairing inactivates retinoblastoma protein and promotes cell cycle dysregulation in multiple myeloma.

Ely S, Di Liberto M, Niesvizky R, Baughn LB, Cho HJ, Hatada EN, Knowles DM, Lane J, Chen-Kiang S.

Cancer Res. 2005 Dec 15;65(24):11345-53.

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