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15664480,16446376,14563899,16999056,14726431,14759231,17296462,15328092,12385678,15177852,12297361,15494258,15784306,15616290,17124993,21888181,15728883,15954852,12501879,18029151,16117975,16236076,11310807,16798401,14759230,14759229,15215226,18809817,18206596,16040621,11776034,16669924,15122171,19296420,22245497,18564685,18339022,17901791,15215115,15303634,16226017,15563517,15964501,19145079,17537866,17939262,15979494,17292577,11086282,14521493,18715733,19734608,17562681,1611648,17933256,17408904,9798478,15360094,9616826,14999620,15933563,11214557,19174454,8155749,17597058,10722438,1391015,9795298,10615328,15288313,16740811,16181747,15489246,10695094,12534334,17980558,17997283,18294246,9795302,11914996,15812119,18583085,17643269,10501315,9869561,17321864,16061111,24477328,12912714,10051963,16490583,16307682,19014842,18835762,20928993,15889358,10826451,16137193,11856980,12673954,15156445,15150184,19320989,12173130,7813493,11535952,25336917,22583782,16230216,15191378,12173142,23179958,12736860,15225866,10804802,19336954,20692869,12888594,12501878,16963678,10348060,27798219,20303716,3587309,18343748,9869562,15980629,11153392,20040690,7824317,15380257,19046911,9798477,24200759,15360092,17496734,9798473,17060515,14687380,14567000,21357586,9798483,8565345,1955697,12839704,20088744,15944847,11354391,15546111,20378315,9559788,15519470,6980050,11075746,23594463,10728733,15360093,12884162,10452654,8737127,12736859,15127371,14679443,12478329,15963272,15610061,16669927,11512085,20144899,10783611,15373084,14745340,17661640,12545592,9758291,1805338,16700188,6752781,21393137,11414411,9802626,19396521,14759228,16231964,12044285,11155733,11731940,22632455,12975069,10585831,2011407,10351928,14558267,12649717,7741782,16816491,23357290,21576444,9784785,14677897,10555936,15696306,21191562,16963679,16376537,11157603,10048679,7996007,10404316,12540219,15728165,9736566,15899177,24920652,22132827,12426976,14963065,8878597,29964229,15086042,10852529,16791660,14556066,20826320,16710005,12607346,12099737,12376038,26476549,29565225,9453979,15493950,4022048,9269388,9797416,12753538,9717154,16038522,23146728,26339883,11332252,14986269,11680107,15233266,9636854,15191393,2927105,10879026,9786488,23101646,19817432,17535061,15038945,7494845,10508029,9412400,11685965,12652400,17674901,8296141,10599260,12477321,28914846,15639407,12775671,17625101,6428194,15308278,14693522,22418755,26562957,31299410,6828173,15127364,27353466,10223160,12697636,20615741,21495834,11882726,10447408,9447898,9044645,9412398,24596,8324023,1854164,10223592,15029125,9597251,35476706,9124825,14583867,21825290,15078597,16917560,11001128,20201405,10918874,9354361,29061311,8757587,8714185,9069540,17035452,8877536,16344922,6572311,9164085,6093520,12672875,11020264,28602108,24475684,7980759,6922944,29391051,11126820,9884510,10451011,15328573,1463527,12583551,23967713,35869729,7811783,9790132,9597259,14727226,23867070,31123008,12973518,9767956,15555824,22214621,22565080,11442214,22914062,30707379,12571540,28653629,10858333,12900532,11098171,11340541,15602489,15049185,18777713,6982440,8904142,15387507,24897821,11810607,24346630,10967962,10755481,9793046,9798482,33617725,29925417,35346836,15000920,35723965,11045112,12226693,9707309,12839702,28502697,15174409,16163420,30640820,10772376,9817526,21068534,11691763,20041929,27471201,11022105,31144241,35748540,21396214,7984204,7497817,11997309,14522390,33280331,26081385,19927487,19236138,17141985,30427713,8071680,11445684,36086715,20557952,32729824,9710998,26946211,25964726,1898949,17261247,3572020,12611187,36251552,35041328,8056109,7784403,19897453,15460193,31060497,3614916,25459192,35425954,15293914,11407356,22293992,11803868,3521521,9122119,33306184,17256185,36112500,11864307,14653975,29882249,28668708,33207229,25047044,15211234,24138433,14725072,28694234,15356470,36897620,1521893,15652032,12481509,26563841,12218924,15555108,24379601,28752505,7075472,8723497,24880449,10506878,26022957,10768060,23745265,27339583,19585443,22390824,30077545,21773659,30639433,10453884,356724,10532085,16807428,18378788,15970176,32127812,32270213,18323184,29681356,6125666,2517879,31329913,34652095,34665460,36638546,25523398,23708793,12120940,18253817,6984780,35525923,34513761,33604613,19246022,30844191,33820548,26032969,23263982,9780593,24479091,32934974,23321603,27151779,34260199,34715350,31874817,29284688,26078191,22504043,29562999,27603302,12420432,23268223,6723636,31049927,34376327,29562998,18475327,25796271,30107281,30025836,31643835,17456921,35705364,28513136,31659061,28780999,12182390,28513497,31275806,6483751,11177725,12732822,28939623,15142478,28272016,35559621,31608221,14764288,32037114,32499044,27252926,28409589,27095876,13670862,10234197,31122653[uid]

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Efficacy of a new pharmacokinetically enhanced formulation of amoxicillin/clavulanate (2000/125 mg) in adults with community-acquired pneumonia caused by Streptococcus pneumoniae, including penicillin-resistant strains.

File TM, Garau J, Jacobs MR, Wynne B, Twynholm M, Berkowitz E. File TM, et al. Int J Antimicrob Agents. 2005 Feb;25(2):110-9. doi: 10.1016/j.ijantimicag.2004.10.007. Int J Antimicrob Agents. 2005. PMID: 15664480 Clinical Trial.

Efficacy and safety of twice-daily pharmacokinetically enhanced amoxicillin/clavulanate (2000/125 mg) in the treatment of adults with community-acquired pneumonia in a country with a high prevalence of penicillin-resistant Streptococcus pneumoniae.

Siquier B, Sánchez-Alvarez J, García-Mendez E, Sabriá M, Santos J, Pallarés R, Twynholm M, Dal-Ré R; 620 Clinical Study Group. Siquier B, et al. J Antimicrob Chemother. 2006 Mar;57(3):536-45. doi: 10.1093/jac/dki480. Epub 2006 Jan 30. J Antimicrob Chemother. 2006. PMID: 16446376 Clinical Trial.

Oral pharmacokinetically enhanced co-amoxiclav 2000/125 mg, twice daily, compared with co-amoxiclav 875/125 mg, three times daily, in the treatment of community-acquired pneumonia in European adults.

Garau J, Twynholm M, Garcia-Mendez E, Siquier B, Rivero A; 557 Clinical Study Group. Garau J, et al. J Antimicrob Chemother. 2003 Nov;52(5):826-36. doi: 10.1093/jac/dkg458. Epub 2003 Oct 16. J Antimicrob Chemother. 2003. PMID: 14563899 Clinical Trial.

Pharmacokinetically enhanced amoxicillin/clavulanate (2,000/125 mg) in acute bacterial rhinosinusitis caused by Streptococcus pneumoniae, including penicillin-resistant strains.

Anon JB, Ferguson B, Twynholm M, Wynne B, Berkowitz E, Poole MD. Anon JB, et al. Ear Nose Throat J. 2006 Aug;85(8):500, 502, 504 passim. Ear Nose Throat J. 2006. PMID: 16999056 Clinical Trial.

Augmentin (amoxicillin/clavulanate) in the treatment of community-acquired respiratory tract infection: a review of the continuing development of an innovative antimicrobial agent.

White AR, Kaye C, Poupard J, Pypstra R, Woodnutt G, Wynne B. White AR, et al. J Antimicrob Chemother. 2004 Jan;53 Suppl 1:i3-20. doi: 10.1093/jac/dkh050. J Antimicrob Chemother. 2004. PMID: 14726431 Review.

Performance in practice: bacteriological efficacy in patients with drug-resistant S. pneumoniae.

Garau J. Garau J. Clin Microbiol Infect. 2004 Apr;10 Suppl 2:28-35. doi: 10.1111/j.1470-9465.2004.00860.x. Clin Microbiol Infect. 2004. PMID: 14759231 Free article.

The efficacy of cefditoren pivoxil in the treatment of lower respiratory tract infections, with a focus on the per-pathogen bacteriologic response in infections caused by Streptococcus pneumoniae and Haemophilus influenzae: a pooled analysis of seven clinical trials.

Granizo JJ, Giménez MJ, Barberán J, Coronel P, Gimeno M, Aguilar L. Granizo JJ, et al. Clin Ther. 2006 Dec;28(12):2061-9. doi: 10.1016/j.clinthera.2006.12.010. Clin Ther. 2006. PMID: 17296462 Review.

Double-blind, randomized study of the efficacy and safety of oral pharmacokinetically enhanced amoxicillin-clavulanate (2,000/125 milligrams) versus those of amoxicillin-clavulanate (875/125 milligrams), both given twice daily for 7 days, in treatment of bacterial community-acquired pneumonia in adults.

File TM Jr, Lode H, Kurz H, Kozak R, Xie H, Berkowitz E; 600 Study Group. File TM Jr, et al. Antimicrob Agents Chemother. 2004 Sep;48(9):3323-31. doi: 10.1128/AAC.48.9.3323-3331.2004. Antimicrob Agents Chemother. 2004. PMID: 15328092 Free PMC article. Clinical Trial.

Outcome of treatment of respiratory tract infections due to Streptococcus pneumoniae, including drug-resistant strains, with pharmacokinetically enhanced amoxycillin/clavulanate.

File TM Jr, Jacobs MR, Poole MD, Wynne B; 546, 547, 548, 549, 550, 551, 556, 557 and 592 Clinical Study Groups. File TM Jr, et al. Int J Antimicrob Agents. 2002 Oct;20(4):235-47. doi: 10.1016/s0924-8579(02)00130-9. Int J Antimicrob Agents. 2002. PMID: 12385678 Clinical Trial.

Evolution of amoxicillin/clavulanate in the treatment of adults with acute bacterial rhinosinusitis and community-acquired pneumonia in response to antimicrobial-resistance patterns.

File TM Jr, Benninger MS, Jacobs MR. File TM Jr, et al. Clin Lab Med. 2004 Jun;24(2):531-51. doi: 10.1016/j.cll.2004.03.003. Clin Lab Med. 2004. PMID: 15177852 Review.

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