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Results: 1 to 20 of 88

1.

Colonization of adjacent stem cell compartments by mutant keratinocytes.

Brash DE, Zhang W, Grossman D, Takeuchi S.

Semin Cancer Biol. 2005 Apr;15(2):97-102. Review.

PMID:
15652454
[PubMed - indexed for MEDLINE]
2.

Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations.

Zhang W, Remenyik E, Zelterman D, Brash DE, Wikonkal NM.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13948-53. Epub 2001 Nov 13.

PMID:
11707578
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

UVB-induced apoptosis drives clonal expansion during skin tumor development.

Zhang W, Hanks AN, Boucher K, Florell SR, Allen SM, Alexander A, Brash DE, Grossman D.

Carcinogenesis. 2005 Jan;26(1):249-57. Epub 2004 Oct 21.

PMID:
15498793
[PubMed - indexed for MEDLINE]
Free PMC Article
4.
5.

Antigen-specific immunity does not mediate acute regression of UVB-induced p53-mutant clones.

Remenyik E, Wikonkál NM, Zhang W, Paliwal V, Brash DE.

Oncogene. 2003 Sep 25;22(41):6369-76.

PMID:
14508517
[PubMed - indexed for MEDLINE]
6.

Fate of UVB-induced p53 mutations in SKH-hr1 mouse skin after discontinuation of irradiation: relationship to skin cancer development.

Melnikova VO, Pacifico A, Chimenti S, Peris K, Ananthaswamy HN.

Oncogene. 2005 Oct 27;24(47):7055-63.

PMID:
16007135
[PubMed - indexed for MEDLINE]
7.

Ultraviolet B irradiation induces expansion of intraepithelial tumor cells in a tissue model of early cancer progression.

Mudgil AV, Segal N, Andriani F, Wang Y, Fusenig NE, Garlick JA.

J Invest Dermatol. 2003 Jul;121(1):191-7.

PMID:
12839581
[PubMed - indexed for MEDLINE]
Free Article
8.

Roles of the transcription factor p53 in keratinocyte carcinomas.

Brash DE.

Br J Dermatol. 2006 May;154 Suppl 1:8-10. Review.

PMID:
16712710
[PubMed - indexed for MEDLINE]
9.

Ultraviolet B light-induced apoptosis in human keratinocytes enriched with epidermal stem cells and normal keratinocytes.

Mei XL, Lian S.

Chin Med J (Engl). 2011 Feb;124(4):591-8.

PMID:
21362287
[PubMed - indexed for MEDLINE]
Free Article
10.

CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice.

Tang X, Zhu Y, Han L, Kim AL, Kopelovich L, Bickers DR, Athar M.

J Clin Invest. 2007 Dec;117(12):3753-64.

PMID:
18060030
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Specific betapapillomaviruses associated with squamous cell carcinoma of the skin inhibit UVB-induced apoptosis of primary human keratinocytes.

Struijk L, van der Meijden E, Kazem S, ter Schegget J, de Gruijl FR, Steenbergen RD, Feltkamp MC.

J Gen Virol. 2008 Sep;89(Pt 9):2303-14. doi: 10.1099/vir.0.83317-0.

PMID:
18753241
[PubMed - indexed for MEDLINE]
Free Article
12.

Differential role of transcription-coupled repair in UVB-induced response of human fibroblasts and keratinocytes.

D'Errico M, Teson M, Calcagnile A, Nardo T, De Luca N, Lazzari C, Soddu S, Zambruno G, Stefanini M, Dogliotti E.

Cancer Res. 2005 Jan 15;65(2):432-8.

PMID:
15695384
[PubMed - indexed for MEDLINE]
Free Article
13.

Preneoplastic lesion growth driven by the death of adjacent normal stem cells.

Chao DL, Eck JT, Brash DE, Maley CC, Luebeck EG.

Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15034-9. doi: 10.1073/pnas.0802211105. Epub 2008 Sep 24.

PMID:
18815380
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Selective DNA damage responses in murine Xpa-/-, Xpc-/- and Csb-/- keratinocyte cultures.

Stout GJ, Oosten Mv, Acherrat FZ, Wit Jd, Vermeij WP, Mullenders LH, Gruijl FR, Backendorf C.

DNA Repair (Amst). 2005 Nov 21;4(11):1337-44. Epub 2005 Sep 22.

PMID:
16182614
[PubMed - indexed for MEDLINE]
15.

Starting and propagating apoptotic signals in UVB irradiated keratinocytes.

Van Laethem A, Garmyn M, Agostinis P.

Photochem Photobiol Sci. 2009 Mar;8(3):299-308. doi: 10.1039/b813346h. Epub 2009 Jan 5. Review.

PMID:
19255669
[PubMed - indexed for MEDLINE]
16.

p53 tumor suppressor gene: a critical molecular target for UV induction and prevention of skin cancer.

Benjamin CL, Ullrich SE, Kripke ML, Ananthaswamy HN.

Photochem Photobiol. 2008 Jan-Feb;84(1):55-62. doi: 10.1111/j.1751-1097.2007.00213.x. Review.

PMID:
18173701
[PubMed - indexed for MEDLINE]
17.

Cellular and molecular events leading to the development of skin cancer.

Melnikova VO, Ananthaswamy HN.

Mutat Res. 2005 Apr 1;571(1-2):91-106. Review.

PMID:
15748641
[PubMed - indexed for MEDLINE]
18.

Signal transducer and activator of transcription 3 is a key regulator of keratinocyte survival and proliferation following UV irradiation.

Sano S, Chan KS, Kira M, Kataoka K, Takagi S, Tarutani M, Itami S, Kiguchi K, Yokoi M, Sugasawa K, Mori T, Hanaoka F, Takeda J, DiGiovanni J.

Cancer Res. 2005 Jul 1;65(13):5720-9.

PMID:
15994947
[PubMed - indexed for MEDLINE]
Free Article
19.

Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa.

Naik E, Michalak EM, Villunger A, Adams JM, Strasser A.

J Cell Biol. 2007 Feb 12;176(4):415-24. Epub 2007 Feb 5.

PMID:
17283183
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A low UVB dose, with the potential to trigger a protective p53-dependent gene program, increases the resilience of keratinocytes against future UVB insults.

Decraene D, Smaers K, Maes D, Matsui M, Declercq L, Garmyn M.

J Invest Dermatol. 2005 Nov;125(5):1026-31.

PMID:
16297205
[PubMed - indexed for MEDLINE]
Free Article

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