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Results: 1 to 20 of 91

1.

Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy.

Angelillo-Scherrer A, Burnier L, Flores N, Savi P, DeMol M, Schaeffer P, Herbert JM, Lemke G, Goff SP, Matsushima GK, Earp HS, Vesin C, Hoylaerts MF, Plaisance S, Collen D, Conway EM, Wehrle-Haller B, Carmeliet P.

J Clin Invest. 2005 Feb;115(2):237-46.

PMID:
15650770
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Role of the growth arrest-specific gene 6 (gas6) product in thrombus stabilization.

Saller F, Burnier L, Schapira M, Angelillo-Scherrer A.

Blood Cells Mol Dis. 2006 May-Jun;36(3):373-8. Epub 2006 Mar 29. Review.

PMID:
16564713
[PubMed - indexed for MEDLINE]
3.

Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization.

Cosemans JM, Van Kruchten R, Olieslagers S, Schurgers LJ, Verheyen FK, Munnix IC, Waltenberger J, Angelillo-Scherrer A, Hoylaerts MF, Carmeliet P, Heemskerk JW.

J Thromb Haemost. 2010 Aug;8(8):1797-808. doi: 10.1111/j.1538-7836.2010.03935.x. Epub 2010 Jun 7.

PMID:
20546121
[PubMed - indexed for MEDLINE]
4.

Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses.

Gould WR, Baxi SM, Schroeder R, Peng YW, Leadley RJ, Peterson JT, Perrin LA.

J Thromb Haemost. 2005 Apr;3(4):733-41. Epub 2005 Feb 23.

PMID:
15733062
[PubMed - indexed for MEDLINE]
5.

Akt is required for Axl-Gas6 signaling to protect cells from E1A-mediated apoptosis.

Lee WP, Wen Y, Varnum B, Hung MC.

Oncogene. 2002 Jan 17;21(3):329-36.

PMID:
11821945
[PubMed - indexed for MEDLINE]
Free Article
6.

Gas6 inhibits apoptosis in vascular smooth muscle: role of Axl kinase and Akt.

Melaragno MG, Cavet ME, Yan C, Tai LK, Jin ZG, Haendeler J, Berk BC.

J Mol Cell Cardiol. 2004 Oct;37(4):881-7.

PMID:
15380678
[PubMed - indexed for MEDLINE]
7.

Gas6 induces proliferation in prostate carcinoma cell lines expressing the Axl receptor.

Sainaghi PP, Castello L, Bergamasco L, Galletti M, Bellosta P, Avanzi GC.

J Cell Physiol. 2005 Jul;204(1):36-44.

PMID:
15605394
[PubMed - indexed for MEDLINE]
8.

Cross-phosphorylation, signaling and proliferative functions of the Tyro3 and Axl receptors in Rat2 cells.

Brown JE, Krodel M, Pazos M, Lai C, Prieto AL.

PLoS One. 2012;7(5):e36800. doi: 10.1371/journal.pone.0036800. Epub 2012 May 14.

PMID:
22606290
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Growth arrest specific gene (GAS) 6 modulates platelet thrombus formation and vascular wall homeostasis and represents an attractive drug target.

Maree AO, Jneid H, Palacios IF, Rosenfield K, MacRae CA, Fitzgerald DJ.

Curr Pharm Des. 2007;13(26):2656-61. Review.

PMID:
17897008
[PubMed - indexed for MEDLINE]
10.

Gas6 anti-apoptotic signaling requires NF-kappa B activation.

Demarchi F, Verardo R, Varnum B, Brancolini C, Schneider C.

J Biol Chem. 2001 Aug 24;276(34):31738-44. Epub 2001 Jun 25.

PMID:
11425860
[PubMed - indexed for MEDLINE]
Free Article
11.

Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy.

Nagai K, Matsubara T, Mima A, Sumi E, Kanamori H, Iehara N, Fukatsu A, Yanagita M, Nakano T, Ishimoto Y, Kita T, Doi T, Arai H.

Kidney Int. 2005 Aug;68(2):552-61.

PMID:
16014032
[PubMed - indexed for MEDLINE]
12.

Beta3 tyrosine phosphorylation in alphaIIbbeta3 (platelet membrane GP IIb-IIIa) outside-in integrin signaling.

Phillips DR, Nannizzi-Alaimo L, Prasad KS.

Thromb Haemost. 2001 Jul;86(1):246-58. Review.

PMID:
11487013
[PubMed - indexed for MEDLINE]
13.

Requirement of phosphatidylinositol 3-kinase-dependent pathway and Src for Gas6-Axl mitogenic and survival activities in NIH 3T3 fibroblasts.

Goruppi S, Ruaro E, Varnum B, Schneider C.

Mol Cell Biol. 1997 Aug;17(8):4442-53.

PMID:
9234702
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Axl/Gas6/NFκB signalling in schwannoma pathological proliferation, adhesion and survival.

Ammoun S, Provenzano L, Zhou L, Barczyk M, Evans K, Hilton DA, Hafizi S, Hanemann CO.

Oncogene. 2014 Jan 16;33(3):336-46. doi: 10.1038/onc.2012.587. Epub 2013 Jan 14.

PMID:
23318455
[PubMed - indexed for MEDLINE]
15.

Gas6-induced tissue factor expression in endothelial cells is mediated through caveolin-1-enriched microdomains.

Laurance S, Aghourian MN, Jiva Lila Z, Lemarié CA, Blostein MD.

J Thromb Haemost. 2014;12(3):395-408. doi: 10.1111/jth.12481.

PMID:
24354620
[PubMed - indexed for MEDLINE]
16.

Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases.

Li Z, Zhang G, Le Breton GC, Gao X, Malik AB, Du X.

J Biol Chem. 2003 Aug 15;278(33):30725-31. Epub 2003 Jun 9.

PMID:
12796499
[PubMed - indexed for MEDLINE]
Free Article
18.

Gas6-axl receptor signaling is regulated by glucose in vascular smooth muscle cells.

Cavet ME, Smolock EM, Ozturk OH, World C, Pang J, Konishi A, Berk BC.

Arterioscler Thromb Vasc Biol. 2008 May;28(5):886-91. doi: 10.1161/ATVBAHA.108.162693. Epub 2008 Feb 21.

PMID:
18292389
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Intracellular signaling pathways involved in Gas6-Axl-mediated survival of endothelial cells.

Hasanbasic I, Cuerquis J, Varnum B, Blostein MD.

Am J Physiol Heart Circ Physiol. 2004 Sep;287(3):H1207-13. Epub 2004 May 6.

PMID:
15130893
[PubMed - indexed for MEDLINE]
Free Article
20.

Gas6-mediated survival in NIH3T3 cells activates stress signalling cascade and is independent of Ras.

Goruppi S, Ruaro E, Varnum B, Schneider C.

Oncogene. 1999 Jul 22;18(29):4224-36.

PMID:
10435635
[PubMed - indexed for MEDLINE]
Free Article

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