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Items: 1 to 20 of 114

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1.

Xenopus laevis CYP17 regulates androgen biosynthesis independent of the cofactor cytochrome b5.

Yang WH, Hammes SR.

J Biol Chem. 2005 Mar 18;280(11):10196-201. Epub 2005 Jan 7.

2.

Ovine steroid 17alpha-hydroxylase cytochrome P450: characteristics of the hydroxylase and lyase activities of the adrenal cortex enzyme.

Swart P, Lombard N, Swart AC, van der Merwe T, Murry BA, Nicol M, Ian Mason J.

Arch Biochem Biophys. 2003 Jan 1;409(1):145-52.

PMID:
12464253
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Baboon cytochrome P450 17alpha-hydroxylase/17,20-lyase (CYP17).

Swart AC, Kolar NW, Lombard N, Mason JI, Swart P.

Eur J Biochem. 2002 Nov;269(22):5608-16.

6.

A single amino acid residue, Ala 105, confers 16alpha-hydroxylase activity to human cytochrome P450 17alpha-hydroxylase/17,20 lyase.

Swart AC, Storbeck KH, Swart P.

J Steroid Biochem Mol Biol. 2010 Apr;119(3-5):112-20. doi: 10.1016/j.jsbmb.2009.12.014. Epub 2010 Jan 4.

PMID:
20043997
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Cytochrome b(5) modulation of 17{alpha} hydroxylase and 17-20 lyase (CYP17) activities in steroidogenesis.

Akhtar MK, Kelly SL, Kaderbhai MA.

J Endocrinol. 2005 Nov;187(2):267-74. Review.

9.

CYP17 mutation E305G causes isolated 17,20-lyase deficiency by selectively altering substrate binding.

Sherbet DP, Tiosano D, Kwist KM, Hochberg Z, Auchus RJ.

J Biol Chem. 2003 Dec 5;278(49):48563-9. Epub 2003 Sep 22.

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Androgen synthesis in a songbird: a study of cyp17 (17alpha-hydroxylase/C17,20-lyase) activity in the zebra finch.

Schlinger BA, Lane NI, Grisham W, Thompson L.

Gen Comp Endocrinol. 1999 Jan;113(1):46-58.

PMID:
9882543
16.

Chimerogenesis in estimation of specificity and pathway directions for cytochrome p45017alpha catalyzed reactions.

Gilep AA, Estabrook RW, Usanov SA.

Biochemistry (Mosc). 2004 Apr;69(4):364-75.

PMID:
15170370
17.

Assessment of the potential of polyphenols as a CYP17 inhibitor free of adverse corticosteroid elevation.

Lin CJ, Cheng LC, Lin TC, Wang CJ, Li LA.

Biochem Pharmacol. 2014 Aug 1;90(3):288-96. doi: 10.1016/j.bcp.2014.05.013. Epub 2014 May 27.

PMID:
24875446
18.

Study of RNA interference inhibiting rat ovarian androgen biosynthesis by depressing 17alpha-hydroxylase/17, 20-lyase activity in vivo.

Li Y, Liang XY, Wei LN, Xiong YL, Yang X, Shi HG, Yang ZH.

Reprod Biol Endocrinol. 2009 Jul 17;7:73. doi: 10.1186/1477-7827-7-73.

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The role of cytochrome b5 in the biosynthesis of androgens by human P450c17.

Katagiri M, Kagawa N, Waterman MR.

Arch Biochem Biophys. 1995 Mar 10;317(2):343-7.

PMID:
7893148
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