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Results: 1 to 20 of 854

1.

Enhancement of topical delivery of drugs via direct penetration by reducing blood flow rate in skin.

Higaki K, Nakayama K, Suyama T, Amnuaikit C, Ogawara K, Kimura T.

Int J Pharm. 2005 Jan 20;288(2):227-33. Epub 2004 Dec 1.

PMID:
15620862
[PubMed - indexed for MEDLINE]
2.

Estimation of intradermal disposition kinetics of drugs: II. Factors determining penetration of drugs from viable skin to muscular layer.

Higaki K, Asai M, Suyama T, Nakayama K, Ogawara K, Kimura T.

Int J Pharm. 2002 Jun 4;239(1-2):129-41.

PMID:
12052698
[PubMed - indexed for MEDLINE]
3.

Estimation of intradermal disposition kinetics of drugs: I. Analysis by compartment model with contralateral tissues.

Nakayama K, Matsuura H, Asai M, Ogawara K, Higaki K, Kimura T.

Pharm Res. 1999 Feb;16(2):302-8.

PMID:
10100318
[PubMed - indexed for MEDLINE]
5.

Drug targeting efficacy to underlying muscle following topical application. I. Evaluation based on a physiological pharmacokinetic model.

Hatanaka T, Manabe E, Ohtsuki T, Okuyama K, Mori M, Okada H, Katayama K, Koizumi T.

Biol Pharm Bull. 2000 Jul;23(7):860-5.

PMID:
10919367
[PubMed - indexed for MEDLINE]
6.

Convective transport of highly plasma protein bound drugs facilitates direct penetration into deep tissues after topical application.

Dancik Y, Anissimov YG, Jepps OG, Roberts MS.

Br J Clin Pharmacol. 2012 Apr;73(4):564-78. doi: 10.1111/j.1365-2125.2011.04128.x. Erratum in: Br J Clin Pharmacol. 2012 May;73(5):841.

PMID:
21999217
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Skin disposition of drugs after topical application in hairless rats.

Yanagimoto G, Hayashi T, Hasegawa T, Seki T, Juni K, Sugibayashi K, Morimoto Y.

Chem Pharm Bull (Tokyo). 1999 Jun;47(6):749-54.

PMID:
10399833
[PubMed - indexed for MEDLINE]
8.

Evaluation of skin penetration of topically applied drugs in humans by cutaneous microdialysis: acyclovir vs. salicylic acid.

Klimowicz A, Farfał S, Bielecka-Grzela S.

J Clin Pharm Ther. 2007 Apr;32(2):143-8.

PMID:
17381664
[PubMed - indexed for MEDLINE]
9.

The role of stratum corneum and dermal microvascular perfusion in penetration and tissue levels of water-soluble drugs investigated by microdialysis.

Morgan CJ, Renwick AG, Friedmann PS.

Br J Dermatol. 2003 Mar;148(3):434-43.

PMID:
12653734
[PubMed - indexed for MEDLINE]
10.

Effects of vasoconstriction on dermal pharmacokinetics and local tissue distribution of compounds.

Singh P, Roberts MS.

J Pharm Sci. 1994 Jun;83(6):783-91.

PMID:
9120806
[PubMed - indexed for MEDLINE]
11.

Percutaneous absorption of salicylates from some commercially available topical products containing methyl salicylate or salicylate salts in rats.

Megwa SA, Benson HA, Roberts MS.

J Pharm Pharmacol. 1995 Nov;47(11):891-6.

PMID:
8708981
[PubMed - indexed for MEDLINE]
12.

Percutaneous and systemic disposition of hexamethylene lauramide and its penetration enhancement effect on hydrocortisone in a rat sandwich skin-flap model.

Tang-Liu DD, Neff J, Zolezio H, Sandri R.

Pharm Res. 1988 Aug;5(8):477-81.

PMID:
3244654
[PubMed - indexed for MEDLINE]
13.

Skin permeability and local tissue concentrations of nonsteroidal anti-inflammatory drugs after topical application.

Singh P, Roberts MS.

J Pharmacol Exp Ther. 1994 Jan;268(1):144-51.

PMID:
8301551
[PubMed - indexed for MEDLINE]
14.

Quantitative determination of percutaneous absorption of radiolabeled drugs in vitro and in vivo by human skin.

Schaefer H, Stüttgen G, Zesch A, Schalla W, Gazith J.

Curr Probl Dermatol. 1978;7:80-94.

PMID:
752460
[PubMed - indexed for MEDLINE]
15.

Topical delivery of cosmetics and drugs. Molecular aspects of percutaneous absorption and delivery.

Förster M, Bolzinger MA, Fessi H, Briançon S.

Eur J Dermatol. 2009 Jul-Aug;19(4):309-23. doi: 10.1684/ejd.2009.0676. Epub 2009 May 14. Review.

PMID:
19443302
[PubMed - indexed for MEDLINE]
16.

Topical skin penetration of diclofenac after single- and multiple-dose application.

Dehghanyar P, Mayer BX, Namiranian K, Mascher H, Müller M, Brunner M.

Int J Clin Pharmacol Ther. 2004 Jul;42(7):353-9.

PMID:
15605686
[PubMed - indexed for MEDLINE]
17.

Topical penetration of piroxicam is dependent on the distribution of the local cutaneous vasculature.

Monteiro-Riviere NA, Inman AO, Riviere JE, McNeill SC, Francoeur ML.

Pharm Res. 1993 Sep;10(9):1326-31.

PMID:
8234171
[PubMed - indexed for MEDLINE]
18.

Potential mechanisms by which a single drink of alcohol can increase transdermal absorption of topically applied chemicals.

Brand RM, Jendrzejewski JL, Charron AR.

Toxicology. 2007 Jun 25;235(3):141-9. Epub 2007 Mar 15.

PMID:
17467136
[PubMed - indexed for MEDLINE]
19.

Dermal and underlying tissue pharmacokinetics of salicylic acid after topical application.

Singh P, Roberts MS.

J Pharmacokinet Biopharm. 1993 Aug;21(4):337-73.

PMID:
8133461
[PubMed - indexed for MEDLINE]
20.

Percutaneous penetration and skin retention of topically applied compounds: an in vitro-in vivo study.

Reifenrath WG, Hawkins GS, Kurtz MS.

J Pharm Sci. 1991 Jun;80(6):526-32.

PMID:
1941541
[PubMed - indexed for MEDLINE]

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