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Items: 1 to 20 of 191


Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs.

Motamedi MR, Verdel A, Colmenares SU, Gerber SA, Gygi SP, Moazed D.

Cell. 2004 Dec 17;119(6):789-802.


Studies on the mechanism of RNAi-dependent heterochromatin assembly.

Moazed D, Bühler M, Buker SM, Colmenares SU, Gerace EL, Gerber SA, Hong EJ, Motamedi MR, Verdel A, Villén J, Gygi SP.

Cold Spring Harb Symp Quant Biol. 2006;71:461-71. Review.


Heterochromatin protein 1 homologue Swi6 acts in concert with Ers1 to regulate RNAi-directed heterochromatin assembly.

Hayashi A, Ishida M, Kawaguchi R, Urano T, Murakami Y, Nakayama J.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6159-64. doi: 10.1073/pnas.1116972109. Epub 2012 Apr 2.


RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production.

Sugiyama T, Cam H, Verdel A, Moazed D, Grewal SI.

Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):152-7. Epub 2004 Dec 22.


Chp1-Tas3 interaction is required to recruit RITS to fission yeast centromeres and for maintenance of centromeric heterochromatin.

Debeauchamp JL, Moses A, Noffsinger VJ, Ulrich DL, Job G, Kosinski AM, Partridge JF.

Mol Cell Biol. 2008 Apr;28(7):2154-66. doi: 10.1128/MCB.01637-07. Epub 2008 Jan 22.


Coupling of double-stranded RNA synthesis and siRNA generation in fission yeast RNAi.

Colmenares SU, Buker SM, Buhler M, Dlakić M, Moazed D.

Mol Cell. 2007 Aug 3;27(3):449-61. Epub 2007 Jul 19.


Heterochromatin and RNAi are required to establish CENP-A chromatin at centromeres.

Folco HD, Pidoux AL, Urano T, Allshire RC.

Science. 2008 Jan 4;319(5859):94-7. doi: 10.1126/science.1150944.


Continuous requirement for the Clr4 complex but not RNAi for centromeric heterochromatin assembly in fission yeast harboring a disrupted RITS complex.

Shanker S, Job G, George OL, Creamer KM, Shaban A, Partridge JF.

PLoS Genet. 2010 Oct 28;6(10):e1001174. doi: 10.1371/journal.pgen.1001174.


Splicing factors facilitate RNAi-directed silencing in fission yeast.

Bayne EH, Portoso M, Kagansky A, Kos-Braun IC, Urano T, Ekwall K, Alves F, Rappsilber J, Allshire RC.

Science. 2008 Oct 24;322(5901):602-6. doi: 10.1126/science.1164029.


Dicer associates with chromatin to repress genome activity in Schizosaccharomyces pombe.

Woolcock KJ, Gaidatzis D, Punga T, Bühler M.

Nat Struct Mol Biol. 2011 Jan;18(1):94-9. doi: 10.1038/nsmb.1935. Epub 2010 Dec 12.


Ers1, a rapidly diverging protein essential for RNA interference-dependent heterochromatic silencing in Schizosaccharomyces pombe.

Rougemaille M, Shankar S, Braun S, Rowley M, Madhani HD.

J Biol Chem. 2008 Sep 19;283(38):25770-3. doi: 10.1074/jbc.C800140200. Epub 2008 Jul 25.


Functional separation of the requirements for establishment and maintenance of centromeric heterochromatin.

Partridge JF, DeBeauchamp JL, Kosinski AM, Ulrich DL, Hadler MJ, Noffsinger VJ.

Mol Cell. 2007 May 25;26(4):593-602.


RNAi-mediated targeting of heterochromatin by the RITS complex.

Verdel A, Jia S, Gerber S, Sugiyama T, Gygi S, Grewal SI, Moazed D.

Science. 2004 Jan 30;303(5658):672-6. Epub 2004 Jan 2. Erratum in: Science. 2013 Oct 11;342(6155):193.


Involvement of the spliceosomal U4 small nuclear RNA in heterochromatic gene silencing at fission yeast centromeres.

Chinen M, Morita M, Fukumura K, Tani T.

J Biol Chem. 2010 Feb 19;285(8):5630-8. doi: 10.1074/jbc.M109.074393. Epub 2009 Dec 14.


On the connection between RNAi and heterochromatin at centromeres.

Lejeune E, Bayne EH, Allshire RC.

Cold Spring Harb Symp Quant Biol. 2010;75:275-83. doi: 10.1101/sqb.2010.75.024. Epub 2011 Feb 2. Review.


RITS-connecting transcription, RNA interference, and heterochromatin assembly in fission yeast.

Creamer KM, Partridge JF.

Wiley Interdiscip Rev RNA. 2011 Sep-Oct;2(5):632-46. doi: 10.1002/wrna.80. Epub 2011 Mar 23. Review.

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