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Results: 1 to 20 of 232

1.

A model of a transmembrane drug-efflux pump from Gram-negative bacteria.

Fernandez-Recio J, Walas F, Federici L, Venkatesh Pratap J, Bavro VN, Miguel RN, Mizuguchi K, Luisi B.

FEBS Lett. 2004 Dec 3;578(1-2):5-9.

PMID:
15581607
[PubMed - indexed for MEDLINE]
Free Article
2.

The AcrB efflux pump: conformational cycling and peristalsis lead to multidrug resistance.

Seeger MA, Diederichs K, Eicher T, Brandstätter L, Schiefner A, Verrey F, Pos KM.

Curr Drug Targets. 2008 Sep;9(9):729-49. Review.

PMID:
18781920
[PubMed - indexed for MEDLINE]
3.

Three's company: component structures bring a closer view of tripartite drug efflux pumps.

Eswaran J, Koronakis E, Higgins MK, Hughes C, Koronakis V.

Curr Opin Struct Biol. 2004 Dec;14(6):741-7. Review.

PMID:
15582398
[PubMed - indexed for MEDLINE]
4.

Structure of the AcrAB-TolC multidrug efflux pump.

Du D, Wang Z, James NR, Voss JE, Klimont E, Ohene-Agyei T, Venter H, Chiu W, Luisi BF.

Nature. 2014 May 22;509(7501):512-5. doi: 10.1038/nature13205. Epub 2014 Apr 20.

PMID:
24747401
[PubMed - indexed for MEDLINE]
5.

Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system.

Touzé T, Eswaran J, Bokma E, Koronakis E, Hughes C, Koronakis V.

Mol Microbiol. 2004 Jul;53(2):697-706.

PMID:
15228545
[PubMed - indexed for MEDLINE]
6.

Assembly and channel opening in a bacterial drug efflux machine.

Bavro VN, Pietras Z, Furnham N, Pérez-Cano L, Fernández-Recio J, Pei XY, Misra R, Luisi B.

Mol Cell. 2008 Apr 11;30(1):114-21. doi: 10.1016/j.molcel.2008.02.015.

PMID:
18406332
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The C-terminal domain of AcrA is essential for the assembly and function of the multidrug efflux pump AcrAB-TolC.

Ge Q, Yamada Y, Zgurskaya H.

J Bacteriol. 2009 Jul;191(13):4365-71. doi: 10.1128/JB.00204-09. Epub 2009 May 1.

PMID:
19411330
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Genetic evidence for functional interactions between TolC and AcrA proteins of a major antibiotic efflux pump of Escherichia coli.

Gerken H, Misra R.

Mol Microbiol. 2004 Nov;54(3):620-31.

PMID:
15491355
[PubMed - indexed for MEDLINE]
9.

Funnel-like hexameric assembly of the periplasmic adapter protein in the tripartite multidrug efflux pump in gram-negative bacteria.

Xu Y, Lee M, Moeller A, Song S, Yoon BY, Kim HM, Jun SY, Lee K, Ha NC.

J Biol Chem. 2011 May 20;286(20):17910-20. doi: 10.1074/jbc.M111.238535. Epub 2011 Mar 29.

PMID:
21454662
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

AcrAB and related multidrug efflux pumps of Escherichia coli.

Nikaido H, Zgurskaya HI.

J Mol Microbiol Biotechnol. 2001 Apr;3(2):215-8. Review.

PMID:
11321576
[PubMed - indexed for MEDLINE]
11.

Drug transport mechanism of the AcrB efflux pump.

Pos KM.

Biochim Biophys Acta. 2009 May;1794(5):782-93. doi: 10.1016/j.bbapap.2008.12.015. Epub 2009 Jan 3. Review.

PMID:
19166984
[PubMed - indexed for MEDLINE]
Free Article
12.

Crystal structure of the periplasmic component of a tripartite macrolide-specific efflux pump.

Yum S, Xu Y, Piao S, Sim SH, Kim HM, Jo WS, Kim KJ, Kweon HS, Jeong MH, Jeon H, Lee K, Ha NC.

J Mol Biol. 2009 Apr 17;387(5):1286-97. doi: 10.1016/j.jmb.2009.02.048. Epub 2009 Feb 28.

PMID:
19254725
[PubMed - indexed for MEDLINE]
13.

Elastic network model-based normal mode analysis reveals the conformational couplings in the tripartite AcrAB-TolC multidrug efflux complex.

Wang B, Weng J, Fan K, Wang W.

Proteins. 2011 Oct;79(10):2936-45. doi: 10.1002/prot.23143. Epub 2011 Aug 26.

PMID:
21905116
[PubMed - indexed for MEDLINE]
14.

Chimeric analysis of the multicomponent multidrug efflux transporters from gram-negative bacteria.

Tikhonova EB, Wang Q, Zgurskaya HI.

J Bacteriol. 2002 Dec;184(23):6499-507.

PMID:
12426337
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Crystal structure of bacterial multidrug efflux transporter AcrB.

Murakami S, Nakashima R, Yamashita E, Yamaguchi A.

Nature. 2002 Oct 10;419(6907):587-93.

PMID:
12374972
[PubMed - indexed for MEDLINE]
16.

A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps.

Lobedanz S, Bokma E, Symmons MF, Koronakis E, Hughes C, Koronakis V.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4612-7. Epub 2007 Mar 5.

PMID:
17360572
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Direct interaction of multidrug efflux transporter AcrB and outer membrane channel TolC detected via site-directed disulfide cross-linking.

Tamura N, Murakami S, Oyama Y, Ishiguro M, Yamaguchi A.

Biochemistry. 2005 Aug 23;44(33):11115-21.

PMID:
16101295
[PubMed - indexed for MEDLINE]
18.

Conformational flexibility in the multidrug efflux system protein AcrA.

Mikolosko J, Bobyk K, Zgurskaya HI, Ghosh P.

Structure. 2006 Mar;14(3):577-87.

PMID:
16531241
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Sequential mechanism of assembly of multidrug efflux pump AcrAB-TolC.

Tikhonova EB, Yamada Y, Zgurskaya HI.

Chem Biol. 2011 Apr 22;18(4):454-63. doi: 10.1016/j.chembiol.2011.02.011.

PMID:
21513882
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

3D structure of AcrB: the archetypal multidrug efflux transporter of Escherichia coli likely captures substrates from periplasm.

Elkins CA, Nikaido H.

Drug Resist Updat. 2003 Feb;6(1):9-13. Review.

PMID:
12654283
[PubMed - indexed for MEDLINE]

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