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Results: 1 to 20 of 996

1.

Serine 332 phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 attenuates insulin signaling.

Liberman Z, Eldar-Finkelman H.

J Biol Chem. 2005 Feb 11;280(6):4422-8. Epub 2004 Nov 30.

PMID:
15574412
[PubMed - indexed for MEDLINE]
Free Article
2.

Sequential phosphorylation of insulin receptor substrate-2 by glycogen synthase kinase-3 and c-Jun NH2-terminal kinase plays a role in hepatic insulin signaling.

Sharfi H, Eldar-Finkelman H.

Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E307-15. Epub 2007 Nov 20.

PMID:
18029441
[PubMed - indexed for MEDLINE]
Free Article
3.

In vivo phosphorylation of insulin receptor substrate 1 at serine 789 by a novel serine kinase in insulin-resistant rodents.

Qiao LY, Zhande R, Jetton TL, Zhou G, Sun XJ.

J Biol Chem. 2002 Jul 19;277(29):26530-9. Epub 2002 May 2.

PMID:
12006586
[PubMed - indexed for MEDLINE]
Free Article
4.
5.

Coordinated phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 and protein kinase C betaII in the diabetic fat tissue.

Liberman Z, Plotkin B, Tennenbaum T, Eldar-Finkelman H.

Am J Physiol Endocrinol Metab. 2008 Jun;294(6):E1169-77. doi: 10.1152/ajpendo.00050.2008. Epub 2008 Apr 22.

PMID:
18430969
[PubMed - indexed for MEDLINE]
Free Article
6.

Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action.

Eldar-Finkelman H, Krebs EG.

Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9660-4.

PMID:
9275179
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation.

Greene MW, Sakaue H, Wang L, Alessi DR, Roth RA.

J Biol Chem. 2003 Mar 7;278(10):8199-211. Epub 2003 Jan 1.

PMID:
12510059
[PubMed - indexed for MEDLINE]
Free Article
8.

Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function.

Paz K, Liu YF, Shorer H, Hemi R, LeRoith D, Quan M, Kanety H, Seger R, Zick Y.

J Biol Chem. 1999 Oct 1;274(40):28816-22.

PMID:
10497255
[PubMed - indexed for MEDLINE]
Free Article
9.

Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor alpha and is involved in the regulation of receptor activity.

Medunjanin S, Hermani A, De Servi B, Grisouard J, Rincke G, Mayer D.

J Biol Chem. 2005 Sep 23;280(38):33006-14. Epub 2005 Aug 1.

PMID:
16076840
[PubMed - indexed for MEDLINE]
Free Article
10.

Nutrient-dependent and insulin-stimulated phosphorylation of insulin receptor substrate-1 on serine 302 correlates with increased insulin signaling.

Giraud J, Leshan R, Lee YH, White MF.

J Biol Chem. 2004 Jan 30;279(5):3447-54. Epub 2003 Nov 17.

PMID:
14623899
[PubMed - indexed for MEDLINE]
Free Article
11.

The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation.

Bax B, Carter PS, Lewis C, Guy AR, Bridges A, Tanner R, Pettman G, Mannix C, Culbert AA, Brown MJ, Smith DG, Reith AD.

Structure. 2001 Dec;9(12):1143-52.

PMID:
11738041
[PubMed - indexed for MEDLINE]
Free Article
12.

Organo-vanadium compounds are potent activators of the protein kinase B signaling pathway and protein tyrosine phosphorylation: mechanism of insulinomimesis.

Mehdi MZ, Srivastava AK.

Arch Biochem Biophys. 2005 Aug 15;440(2):158-64.

PMID:
16055077
[PubMed - indexed for MEDLINE]
13.

Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612.

De Fea K, Roth RA.

Biochemistry. 1997 Oct 21;36(42):12939-47.

PMID:
9335553
[PubMed - indexed for MEDLINE]
14.

Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 in insulin receptor substrate-1.

Müssig K, Staiger H, Fiedler H, Moeschel K, Beck A, Kellerer M, Häring HU.

J Biol Chem. 2005 Sep 23;280(38):32693-9. Epub 2005 Jul 29.

PMID:
16055440
[PubMed - indexed for MEDLINE]
Free Article
15.
17.

C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser 612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport.

D'Alessandris C, Lauro R, Presta I, Sesti G.

Diabetologia. 2007 Apr;50(4):840-9. Epub 2007 Feb 6.

PMID:
17279354
[PubMed - indexed for MEDLINE]
18.

IRS-1 tyrosine phosphorylation reflects insulin-induced metabolic and mitogenic responses in 3T3-L1 pre-adipocytes.

Telting D, van der Zon GC, Dorrestijn J, Maassen JA.

Arch Physiol Biochem. 2001 Feb;109(1):52-62.

PMID:
11471071
[PubMed - indexed for MEDLINE]
19.

Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.

Lingohr MK, Dickson LM, McCuaig JF, Hugl SR, Twardzik DR, Rhodes CJ.

Diabetes. 2002 Apr;51(4):966-76.

PMID:
11916914
[PubMed - indexed for MEDLINE]
Free Article
20.

YMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites.

Myers MG Jr, Zhang Y, Aldaz GA, Grammer T, Glasheen EM, Yenush L, Wang LM, Sun XJ, Blenis J, Pierce JH, White MF.

Mol Cell Biol. 1996 Aug;16(8):4147-55.

PMID:
8754813
[PubMed - indexed for MEDLINE]
Free PMC Article

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