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Results: 1 to 20 of 121

1.

Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine.

Gearry RB, Roberts RL, Barclay ML, Kennedy MA.

Pharmacogenetics. 2004 Nov;14(11):779-81.

PMID:
15564886
[PubMed - indexed for MEDLINE]
2.

Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).

Marinaki AM, Ansari A, Duley JA, Arenas M, Sumi S, Lewis CM, Shobowale-Bakre el-M, Escuredo E, Fairbanks LD, Sanderson JD.

Pharmacogenetics. 2004 Mar;14(3):181-7.

PMID:
15167706
[PubMed - indexed for MEDLINE]
3.

Inosine triphosphate pyrophosphatase and thiopurine s-methyltransferase genotypes relationship to azathioprine-induced myelosuppression.

Zelinkova Z, Derijks LJ, Stokkers PC, Vogels EW, van Kampen AH, Curvers WL, Cohn D, van Deventer SJ, Hommes DW.

Clin Gastroenterol Hepatol. 2006 Jan;4(1):44-9.

PMID:
16431304
[PubMed - indexed for MEDLINE]
4.

Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study.

von Ahsen N, Armstrong VW, Behrens C, von Tirpitz C, Stallmach A, Herfarth H, Stein J, Bias P, Adler G, Shipkova M, Oellerich M, Kruis W, Reinshagen M, Schütz E.

Clin Chem. 2005 Dec;51(12):2282-8. Epub 2005 Oct 7. Erratum in: Clin Chem. 2006 Aug;52(8):1628. Schütz, Ekkehard [added].

PMID:
16214825
[PubMed - indexed for MEDLINE]
Free Article
5.

Pharmacogenetics of thiopurine therapy in paediatric IBD patients.

De Ridder L, Van Dieren JM, Van Deventer HJ, Stokkers PC, Van der Woude JC, Van Vuuren AJ, Benninga MA, Escher JC, Hommes DW.

Aliment Pharmacol Ther. 2006 Apr 15;23(8):1137-41.

PMID:
16611274
[PubMed - indexed for MEDLINE]
Free Article
6.

Association between inosine triphosphate pyrophosphohydrolase deficiency and azathioprine-related adverse drug reactions in the Chinese kidney transplant recipients.

Xiong H, Xin HW, Wu XC, Li Q, Xiong L, Yu AR.

Fundam Clin Pharmacol. 2010 Jun;24(3):393-400. doi: 10.1111/j.1472-8206.2009.00770.x. Epub 2009 Aug 13.

PMID:
19682085
[PubMed - indexed for MEDLINE]
7.

Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment.

Uchiyama K, Nakamura M, Kubota T, Yamane T, Fujise K, Tajiri H.

J Gastroenterol. 2009;44(3):197-203. doi: 10.1007/s00535-008-2307-1. Epub 2009 Feb 13.

PMID:
19214663
[PubMed - indexed for MEDLINE]
8.

Mutation in the ITPA gene predicts intolerance to azathioprine.

Marinaki AM, Duley JA, Arenas M, Ansari A, Sumi S, Lewis CM, Shobowale-Bakre M, Fairbanks LD, Sanderson J.

Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(8-9):1393-7.

PMID:
15571265
[PubMed - indexed for MEDLINE]
9.

TPMT but not ITPA gene polymorphism influences the risk of azathioprine intolerance in renal transplant recipients.

Kurzawski M, Dziewanowski K, Lener A, Drozdzik M.

Eur J Clin Pharmacol. 2009 May;65(5):533-40. doi: 10.1007/s00228-009-0630-y. Epub 2009 Feb 20.

PMID:
19229528
[PubMed - indexed for MEDLINE]
10.

Pharmacogenetic association with adverse drug reactions to azathioprine immunosuppressive therapy following liver transplantation.

Breen DP, Marinaki AM, Arenas M, Hayes PC.

Liver Transpl. 2005 Jul;11(7):826-33. Erratum in: Liver Transpl. 2005 Sep;11(9):1150.

PMID:
15973722
[PubMed - indexed for MEDLINE]
Free Article
11.

Allele frequency of thiopurine methyltransferase and inosine triphosphate pyrophosphatase gene polymorphisms in Korean patients with inflammatory bowel diseases.

Cheon JH, Kim JH, Kim BY, Kim SW, Hong SY, Eun CS, Hong SS, Byeon JS, Kim TI, Han DS, Yang SK, Lee KR, Kim WH.

Hepatogastroenterology. 2009 Mar-Apr;56(90):421-3.

PMID:
19579612
[PubMed - indexed for MEDLINE]
12.

Association between adverse effects under azathioprine therapy and inosine triphosphate pyrophosphatase activity in patients with chronic inflammatory bowel disease.

Shipkova M, Franz J, Abe M, Klett C, Wieland E, Andus T.

Ther Drug Monit. 2011 Jun;33(3):321-8. doi: 10.1097/FTD.0b013e31821a7c34.

PMID:
21544018
[PubMed - indexed for MEDLINE]
13.

A pharmacogenetics study of TPMT and ITPA genes detects a relationship with side effects and clinical response in patients with inflammatory bowel disease receiving Azathioprine.

Zabala-Fernández W, Barreiro-de Acosta M, Echarri A, Carpio D, Lorenzo A, Castro J, Martínez-Ares D, Pereira S, Martin-Granizo I, Corton M, Carracedo A, Barros F.

J Gastrointestin Liver Dis. 2011 Sep;20(3):247-53.

PMID:
21961091
[PubMed - indexed for MEDLINE]
Free Article
14.

No induction of thiopurine methyltransferase during thiopurine treatment in inflammatory bowel disease.

Lindqvist M, Hindorf U, Almer S, Söderkvist P, Ström M, Hjortswang H, Peterson C.

Nucleosides Nucleotides Nucleic Acids. 2006;25(9-11):1033-7.

PMID:
17065060
[PubMed - indexed for MEDLINE]
15.

Thiopurine-methyltransferase and inosine triphosphate pyrophosphatase polymorphism in a liver transplant recipient developing nodular regenerative hyperplasia on low-dose azathioprine.

Buster EH, van Vuuren HJ, Zondervan PE, Metselaar HJ, Tilanus HW, de Man RA.

Eur J Gastroenterol Hepatol. 2008 Jan;20(1):68-72.

PMID:
18090994
[PubMed - indexed for MEDLINE]
16.

Meta-analysis: Inosine triphosphate pyrophosphatase polymorphisms and thiopurine toxicity in the treatment of inflammatory bowel disease.

Van Dieren JM, Hansen BE, Kuipers EJ, Nieuwenhuis EE, Van der Woude CJ.

Aliment Pharmacol Ther. 2007 Sep 1;26(5):643-52. Review.

PMID:
17697198
[PubMed - indexed for MEDLINE]
Free Article
17.

Correlation of genotypes for thiopurine methyltransferase and inosine triphosphate pyrophosphatase with long-term clinical outcomes in Korean patients with inflammatory bowel diseases during treatment with thiopurine drugs.

Jung YS, Cheon JH, Park JJ, Moon CM, Kim ES, Lee JH, Kim SW, Kim JH, Hong SP, Kim TI, Kim WH.

J Hum Genet. 2010 Feb;55(2):121-3. doi: 10.1038/jhg.2009.125. Epub 2009 Dec 4.

PMID:
19960028
[PubMed - indexed for MEDLINE]
18.

Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel disease.

Ansari A, Arenas M, Greenfield SM, Morris D, Lindsay J, Gilshenan K, Smith M, Lewis C, Marinaki A, Duley J, Sanderson J.

Aliment Pharmacol Ther. 2008 Oct 15;28(8):973-83. doi: 10.1111/j.1365-2036.2008.03788.x.

PMID:
18616518
[PubMed - indexed for MEDLINE]
19.

Analysis of ITPA phenotype-genotype correlation in the Bulgarian population revealed a novel gene variant in exon 6.

Atanasova S, Shipkova M, Svinarov D, Mladenova A, Genova M, Wieland E, Oellerich M, von Ahsen N.

Ther Drug Monit. 2007 Feb;29(1):6-10.

PMID:
17304144
[PubMed - indexed for MEDLINE]
20.

Measurement of erythrocyte inosine triphosphate pyrophosphohydrolase (ITPA) activity by HPLC and correlation of ITPA genotype-phenotype in a Caucasian population.

Shipkova M, Lorenz K, Oellerich M, Wieland E, von Ahsen N.

Clin Chem. 2006 Feb;52(2):240-7. Epub 2005 Dec 29.

PMID:
16384889
[PubMed - indexed for MEDLINE]
Free Article

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