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15557115,15039779,17875746,26658558,23264634,23295456,24857736,12543930,26541386,24931410,17630825,17418788,28791779,29033133,33790297,21447814,35098921,24144701,18845677,12917401,22008473,21659568,17506639,17182855,28864541,12604785,15813752,25692596,29374059,28669824,28506890,34639238,12403813,22357553,20627572,11716302,25778920,19098896,24213245,19801417,24857723,33838103,34473567,21995724,33336681,26311873,21880896,21647294,35491934,31807700,26489467,24626154,31375530,28887410,17082456,25562883,30704069,22901806,27673359,17916694,31262825,23202855,27932586,17897934,26530420,26338152,36040030,33589493,23907389,21576265,20498018,24857727,31723007,18688269,23840761,26791761,16045929,12082159,12552102,25413348,32453403,16739728,16783364,24739174,20074073,27939291,16820771,32794558,30902367,10523319,12524319,17347149,16675447,22250199,25797490,18485366,12654904,32029894,17079785,36302971,24857739,33909044,11248054,24788517,24165935,22798490,31753862,28883038,24165936,32696372,12062099,15574330,19278659,35923096,11104765,33548309,19414608,22031293,23427268,19273614,20305392,29590630,15294903,33856346,29429880,17724120,24705649,21327077,27091992,17544521,33053148,17724121,15143180,14729961,28068389,23090414,16118201,26371551,22577827,33333016,25942622,20032305,16461911,20379223,35412248,27999437,23404701,22419078,35089308,22020388,30942170,15039784,12215173,29899397,28515232,12885761,26519791,34237287,12372823,28720791,11425876,15137937,22213798,28384479,33268786,29439116,16682526,26878241,18046406,29997211,16314397,23170199,16962132,25057022,26344569,22110128,26456112,14993277,31913454,31211995,34339633,32622019,36000978,31170156,26492198,24505056,23669120,23795296,25748139,21346187,21576266,29496964,11867631,12032079,25602437,33912945,27136131,23332057,29958108,30110828,27697925,20197273,21987633,11387327,19198597,12471904,20647373,28402725,34201715,16361228,22326858,24558427,17116750,32879490,12411502,21673865,30837289,18824568,28858378,21690354,12509452,26709543,16365162,11583626,18282135,18498078,19759143,31914646,18974315,23043112,19680228,11208130,11412846,30342747,14568002,27147062,31170242,34127448,20110349,22902403,21326820,25139911,25435324,28579449,19548985,29972802,20368455,35412238,20371601,12600309,12191473,37099395,24152732,26046137,19524430,29809148,35373738,12559755,15459192,22898497,12082158,27273515,25165147,20566687,20453848,19141610,19414609,34982960,30471692,31839259,28530826,35593254,28202688,35735140,21332387,16769882,23066030,29632211,23645671,23979602,22171326,14697200,24657998,32051285,9725905,26432634,20016074,16987955,26902931,24297441,30700705,12937276,19596381,22100335,18544502,19855394,20348449,26041935,21685911,21326821,25229147,17726064,28069952,34995711,22406340,23499021,23542339,23725695,31157618,35563762,28734076,23438601,12538759,28386019,12067655,21528351,19507204,27470900,27863235,17538013,33217650,37066338,25940904,23049930,26783300,30017917,26891179,24929341,27839866,31626769,24943837,20421988,34097873,12637516,24038953,22411995,29916017,30496303,34324340,36220102,29572326,21167872,14697343,12656985,36138110,15041643,34193851,22110603,35408855,21326944,23731471,21327078,31213386,35171083,35293775,11853995,30021831,19576787,28138739,19255571,37100914,14517296,30883195,23238392,27185238,22331846,34557894,34010011,34944108,31407282,22665783,29442997,16000377,14693424,22196930,17161424,24066078,21402022,26434509,26944195,25646085,17448464,24279500,22529346,34504007,22718353,35159217,22387213,29176624,24615017,35058649,35412235,36257947,25999061,15557117,14755266,25691464,12791264,19706512,35013558,20858414,28179529,26694838,33495357,35754154,33617830,27058170,34782239,21327089,25470426,24637838,20651645,21499242,29062044,20630994,22046461,24563356,12189172,32917881,11952838,36765044,10801463,26967283,20368288,29531309,35328452,20547758,27658570,8311839,27856507,20811366,31673318,36757893,15210706,28949296,34723966,8816998,29539637,29695777,17164246,28506892,21925109,18045934,36222862,31285298,24574455,11129789,27071718,22851316,24530809,35488039,32553207,24806932,35269721,15741174,32022936,27194810,22480613,21326823,31543372,12872733,19680227,32086712,19680225,24138862,34312247,26894898,25253717,11756420,29116248,30488537,21961597,26571558,22264802,28638491,29217659,33323374,29117531,28734734,23047597,21502404,21347375,21228627,26705895,23479651,12065587,20513410,30943371,35501995,21189294,24282617,19767751,9695836,30456374,26719328,27623377,27389988,20304795,32096308,36515990,27849094,18060562,34002694,34282823,31834369,34394173,34322491,21030234,23539416,32422829,35314668,17693250,21843462,32988961,33428378,8896451,20409487,27198189,35412250,36310199,34570098,35681009,22036567,36050301,36070178,29431587,35412233,32168597,33556822,14723841,16402261,35306250,21576391,26826378,18852071,12791277,18404152,28700925,17656361,37064528,33502100,20844488,28463551,24384931,28473267,27538565,24084236,19641729,27283299,26422820,32667780,11509251,21556326,34572142,19819881,34399020,2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The FG-repeat asymmetry of the nuclear pore complex is dispensable for bulk nucleocytoplasmic transport in vivo.

Zeitler B, Weis K. Zeitler B, et al. J Cell Biol. 2004 Nov 22;167(4):583-90. doi: 10.1083/jcb.200407156. J Cell Biol. 2004. PMID: 15557115 Free PMC article.

Minimal nuclear pore complexes define FG repeat domains essential for transport.

Strawn LA, Shen T, Shulga N, Goldfarb DS, Wente SR. Strawn LA, et al. Nat Cell Biol. 2004 Mar;6(3):197-206. doi: 10.1038/ncb1097. Epub 2004 Feb 22. Nat Cell Biol. 2004. PMID: 15039779

Nuclear mRNA export requires specific FG nucleoporins for translocation through the nuclear pore complex.

Terry LJ, Wente SR. Terry LJ, et al. J Cell Biol. 2007 Sep 24;178(7):1121-32. doi: 10.1083/jcb.200704174. Epub 2007 Sep 17. J Cell Biol. 2007. PMID: 17875746 Free PMC article.

Nucleoporin's Like Charge Regions Are Major Regulators of FG Coverage and Dynamics Inside the Nuclear Pore Complex.

Peyro M, Soheilypour M, Ghavami A, Mofrad MR. Peyro M, et al. PLoS One. 2015 Dec 11;10(12):e0143745. doi: 10.1371/journal.pone.0143745. eCollection 2015. PLoS One. 2015. PMID: 26658558 Free PMC article.

Several phenylalanine-glycine motives in the nucleoporin Nup214 are essential for binding of the nuclear export receptor CRM1.

Roloff S, Spillner C, Kehlenbach RH. Roloff S, et al. J Biol Chem. 2013 Feb 8;288(6):3952-63. doi: 10.1074/jbc.M112.433243. Epub 2012 Dec 21. J Biol Chem. 2013. PMID: 23264634 Free PMC article.

A subset of FG-nucleoporins is necessary for efficient Msn5-mediated nuclear protein export.

Finn EM, DeRoo EP, Clement GW, Rao S, Kruse SE, Kokanovich KM, Belanger KD. Finn EM, et al. Biochim Biophys Acta. 2013 May;1833(5):1096-103. doi: 10.1016/j.bbamcr.2012.12.020. Epub 2013 Jan 4. Biochim Biophys Acta. 2013. PMID: 23295456 Free PMC article.

Assessing regulated nuclear transport in Saccharomyces cerevisiae.

Ptak C, Wozniak RW. Ptak C, et al. Methods Cell Biol. 2014;122:311-30. doi: 10.1016/B978-0-12-417160-2.00014-X. Methods Cell Biol. 2014. PMID: 24857736

Deciphering networks of protein interactions at the nuclear pore complex.

Allen NP, Patel SS, Huang L, Chalkley RJ, Burlingame A, Lutzmann M, Hurt EC, Rexach M. Allen NP, et al. Mol Cell Proteomics. 2002 Dec;1(12):930-46. doi: 10.1074/mcp.t200012-mcp200. Mol Cell Proteomics. 2002. PMID: 12543930 Free article.

Evolutionarily Conserved Sequence Features Regulate the Formation of the FG Network at the Center of the Nuclear Pore Complex.

Peyro M, Soheilypour M, Lee BL, Mofrad MR. Peyro M, et al. Sci Rep. 2015 Nov 6;5:15795. doi: 10.1038/srep15795. Sci Rep. 2015. PMID: 26541386 Free PMC article.

Nucleoporin FG domains facilitate mRNP remodeling at the cytoplasmic face of the nuclear pore complex.

Adams RL, Terry LJ, Wente SR. Adams RL, et al. Genetics. 2014 Aug;197(4):1213-24. doi: 10.1534/genetics.114.164012. Epub 2014 Jun 14. Genetics. 2014. PMID: 24931410 Free PMC article.

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