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Antiarthritic effect of bee venom: inhibition of inflammation mediator generation by suppression of NF-kappaB through interaction with the p50 subunit.

Park HJ, Lee SH, Son DJ, Oh KW, Kim KH, Song HS, Kim GJ, Oh GT, Yoon DY, Hong JT.

Arthritis Rheum. 2004 Nov;50(11):3504-15.


Melittin inhibits inflammatory target gene expression and mediator generation via interaction with IkappaB kinase.

Park HJ, Son DJ, Lee CW, Choi MS, Lee US, Song HS, Lee JM, Hong JT.

Biochem Pharmacol. 2007 Jan 15;73(2):237-47. Epub 2006 Sep 29.


JNK pathway is involved in the inhibition of inflammatory target gene expression and NF-kappaB activation by melittin.

Park HJ, Lee HJ, Choi MS, Son DJ, Song HS, Song MJ, Lee JM, Han SB, Kim Y, Hong JT.

J Inflamm (Lond). 2008 May 29;5:7. doi: 10.1186/1476-9255-5-7.


Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia.

Moon DO, Park SY, Lee KJ, Heo MS, Kim KC, Kim MO, Lee JD, Choi YH, Kim GY.

Int Immunopharmacol. 2007 Aug;7(8):1092-101. Epub 2007 May 2.


Anti-inflammatory effects of sinapic acid through the suppression of inducible nitric oxide synthase, cyclooxygase-2, and proinflammatory cytokines expressions via nuclear factor-kappaB inactivation.

Yun KJ, Koh DJ, Kim SH, Park SJ, Ryu JH, Kim DG, Lee JY, Lee KT.

J Agric Food Chem. 2008 Nov 12;56(21):10265-72. doi: 10.1021/jf802095g. Epub 2008 Oct 9.


Anti-inflammatory and arthritic effects of thiacremonone, a novel sulfur compound isolated from garlic via inhibition of NF-kappaB.

Ban JO, Oh JH, Kim TM, Kim DJ, Jeong HS, Han SB, Hong JT.

Arthritis Res Ther. 2009;11(5):R145. doi: 10.1186/ar2819. Epub 2009 Sep 30.


Phellinus linteus inhibits inflammatory mediators by suppressing redox-based NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophage.

Kim HG, Yoon DH, Lee WH, Han SK, Shrestha B, Kim CH, Lim MH, Chang W, Lim S, Choi S, Song WO, Sung JM, Hwang KC, Kim TW.

J Ethnopharmacol. 2007 Dec 3;114(3):307-15. Epub 2007 Aug 19.


Anti-inflammatory activity of prosapogenin methyl ester of platycodin D via nuclear factor-kappaB pathway inhibition.

Chung JW, Noh EJ, Zhao HL, Sim JS, Ha YW, Shin EM, Lee EB, Cheong CS, Kim YS.

Biol Pharm Bull. 2008 Nov;31(11):2114-20.


Anti-inflammatory effect of allylpyrocatechol in LPS-induced macrophages is mediated by suppression of iNOS and COX-2 via the NF-kappaB pathway.

Sarkar D, Saha P, Gamre S, Bhattacharjee S, Hariharan C, Ganguly S, Sen R, Mandal G, Chattopadhyay S, Majumdar S, Chatterjee M.

Int Immunopharmacol. 2008 Sep;8(9):1264-71. doi: 10.1016/j.intimp.2008.05.003. Epub 2008 Jun 6.


Melittin inhibits vascular smooth muscle cell proliferation through induction of apoptosis via suppression of nuclear factor-kappaB and Akt activation and enhancement of apoptotic protein expression.

Son DJ, Ha SJ, Song HS, Lim Y, Yun YP, Lee JW, Moon DC, Park YH, Park BS, Song MJ, Hong JT.

J Pharmacol Exp Ther. 2006 May;317(2):627-34. Epub 2006 Jan 9.


Cobrotoxin inhibits NF-kappa B activation and target gene expression through reaction with NF-kappa B signal molecules.

Park MH, Song HS, Kim KH, Son DJ, Lee SH, Yoon DY, Kim Y, Park IY, Song S, Hwang BY, Jung JK, Hong JT.

Biochemistry. 2005 Jun 14;44(23):8326-36.


Effects of bee venom on the pro-inflammatory responses in RAW264.7 macrophage cell line.

Jang HS, Kim SK, Han JB, Ahn HJ, Bae H, Min BI.

J Ethnopharmacol. 2005 May 13;99(1):157-60.


Potent anti-inflammatory effect of a novel furan-2,5-dione derivative, BPD, mediated by dual suppression of COX-2 activity and LPS-induced inflammatory gene expression via NF-κB inactivation.

Shin JS, Park SJ, Ryu S, Kang HB, Kim TW, Choi JH, Lee JY, Cho YW, Lee KT.

Br J Pharmacol. 2012 Mar;165(6):1926-40. doi: 10.1111/j.1476-5381.2011.01670.x.


Bee venom suppresses LPS-mediated NO/iNOS induction through inhibition of PKC-alpha expression.

Lee KG, Cho HJ, Bae YS, Park KK, Choe JY, Chung IK, Kim M, Yeo JH, Park KH, Lee YS, Kim CH, Chang YC.

J Ethnopharmacol. 2009 May 4;123(1):15-21. doi: 10.1016/j.jep.2009.02.044. Epub 2009 Mar 9.


Bee venom suppresses PMA-mediated MMP-9 gene activation via JNK/p38 and NF-kappaB-dependent mechanisms.

Cho HJ, Jeong YJ, Park KK, Park YY, Chung IK, Lee KG, Yeo JH, Han SM, Bae YS, Chang YC.

J Ethnopharmacol. 2010 Feb 17;127(3):662-8. doi: 10.1016/j.jep.2009.12.007. Epub 2009 Dec 5.


Luteolin suppresses inflammation-associated gene expression by blocking NF-kappaB and AP-1 activation pathway in mouse alveolar macrophages.

Chen CY, Peng WH, Tsai KD, Hsu SL.

Life Sci. 2007 Nov 30;81(23-24):1602-14. Epub 2007 Oct 5.


Inhibition of LPS-induced iNOS, COX-2 and cytokines expression by poncirin through the NF-kappaB inactivation in RAW 264.7 macrophage cells.

Kim JB, Han AR, Park EY, Kim JY, Cho W, Lee J, Seo EK, Lee KT.

Biol Pharm Bull. 2007 Dec;30(12):2345-51.

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