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Results: 1 to 20 of 345

1.

[Gene therapy of tyrosine hydroxylase, aromatic L-amino acid decarboxylase, and GTP cyclohydrolase genes in rat model of Parkinson's disease].

Lu LL, Su Y, Duan CL, Zhao CL, Su YJ, Wu J, Zhao HY, Xu QY, Yang H.

Zhonghua Yi Xue Za Zhi. 2004 Sep 17;84(18):1528-32. Chinese.

PMID:
15500713
[PubMed - indexed for MEDLINE]
2.

Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease.

Shen Y, Muramatsu SI, Ikeguchi K, Fujimoto KI, Fan DS, Ogawa M, Mizukami H, Urabe M, Kume A, Nagatsu I, Urano F, Suzuki T, Ichinose H, Nagatsu T, Monahan J, Nakano I, Ozawa K.

Hum Gene Ther. 2000 Jul 20;11(11):1509-19.

PMID:
10945765
[PubMed - indexed for MEDLINE]
3.

Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes.

Muramatsu S, Fujimoto K, Ikeguchi K, Shizuma N, Kawasaki K, Ono F, Shen Y, Wang L, Mizukami H, Kume A, Matsumura M, Nagatsu I, Urano F, Ichinose H, Nagatsu T, Terao K, Nakano I, Ozawa K.

Hum Gene Ther. 2002 Feb 10;13(3):345-54.

PMID:
11860702
[PubMed - indexed for MEDLINE]
4.

Role of aromatic L-amino acid decarboxylase for dopamine replacement by genetically modified fibroblasts in a rat model of Parkinson's disease.

Wachtel SR, Bencsics C, Kang UJ.

J Neurochem. 1997 Nov;69(5):2055-63.

PMID:
9349551
[PubMed - indexed for MEDLINE]
5.
6.

Adeno-associated virus vector-mediated triple gene transfer of dopamine synthetic enzymes.

Fan D, Shen Y, Kang D, Nakano I, Ozawa K.

Chin Med J (Engl). 2001 Dec;114(12):1276-9.

PMID:
11793852
[PubMed - indexed for MEDLINE]
Free Article
7.

[Expression and assessment of double genes of tyrosine hydroxylase gene and aromatic L-amino acid decarboxylase gene in vitro].

Su Y, Duan CL, Zhao CL, Zhao HY, Xu QY, Yang H.

Sheng Li Xue Bao. 2003 Oct 25;55(5):583-8. Chinese.

PMID:
14566408
[PubMed - indexed for MEDLINE]
Free Article
9.

Therapeutic benefit of TH-engineered mesenchymal stem cells for Parkinson's disease.

Lu L, Zhao C, Liu Y, Sun X, Duan C, Ji M, Zhao H, Xu Q, Yang H.

Brain Res Brain Res Protoc. 2005 May;15(1):46-51. Epub 2005 Apr 22.

PMID:
15878150
[PubMed - indexed for MEDLINE]
10.

Behavioral recovery in 6-hydroxydopamine-lesioned rats by cotransduction of striatum with tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes using two separate adeno-associated virus vectors.

Fan DS, Ogawa M, Fujimoto KI, Ikeguchi K, Ogasawara Y, Urabe M, Nishizawa M, Nakano I, Yoshida M, Nagatsu I, Ichinose H, Nagatsu T, Kurtzman GJ, Ozawa K.

Hum Gene Ther. 1998 Nov 20;9(17):2527-35.

PMID:
9853519
[PubMed - indexed for MEDLINE]
11.

Cotransduction of tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes into cultured striatal cells using adeno-associated virus vectors.

Fan D, Kang D, Ogawa M, Nakano I, Nagatsu T, Kurtzman GJ, Ozawa K.

Chin Med J (Engl). 1998 Dec;111(12):1111-3.

PMID:
11263376
[PubMed - indexed for MEDLINE]
Free Article
12.

Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease.

Mandel RJ, Rendahl KG, Spratt SK, Snyder RO, Cohen LK, Leff SE.

J Neurosci. 1998 Jun 1;18(11):4271-84.

PMID:
9592104
[PubMed - indexed for MEDLINE]
Free Article
13.

The assays of activities and function of TH, AADC, and GCH1 and their potential use in ex vivo gene therapy of PD.

Duan CL, Su Y, Zhao CL, Lu LL, Xu QY, Yang H.

Brain Res Brain Res Protoc. 2005 Dec;16(1-3):37-43.

PMID:
16338639
[PubMed - indexed for MEDLINE]
14.

A site-specific mutation of tyrosine hydroxylase reduces feedback inhibition by dopamine in genetically modified cells grafted in parkinsonian rats.

Chang JW, Lee WY, Milstien S, Kang UJ.

J Neurochem. 2002 Oct;83(1):141-9.

PMID:
12358737
[PubMed - indexed for MEDLINE]
15.

Functional effect of adeno-associated virus mediated gene transfer of aromatic L-amino acid decarboxylase into the striatum of 6-OHDA-lesioned rats.

Sánchez-Pernaute R, Harvey-White J, Cunningham J, Bankiewicz KS.

Mol Ther. 2001 Oct;4(4):324-30.

PMID:
11592835
[PubMed - indexed for MEDLINE]
Free Article
16.

In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector.

During MJ, Samulski RJ, Elsworth JD, Kaplitt MG, Leone P, Xiao X, Li J, Freese A, Taylor JR, Roth RH, Sladek JR Jr, O'Malley KL, Redmond DE Jr.

Gene Ther. 1998 Jun;5(6):820-7.

PMID:
9747462
[PubMed - indexed for MEDLINE]
Free Article
17.

Significant behavioral recovery in Parkinson's disease model by direct intracerebral gene transfer using continuous injection of a plasmid DNA-liposome complex.

Imaoka T, Date I, Ohmoto T, Nagatsu T.

Hum Gene Ther. 1998 May 1;9(7):1093-102.

PMID:
9607420
[PubMed - indexed for MEDLINE]
18.

[Gene therapy for Parkinson's disease: studies in animal models].

Muramatsu S.

Rinsho Shinkeigaku. 2001 Dec;41(12):1157-9. Review. Japanese.

PMID:
12235825
[PubMed - indexed for MEDLINE]
19.

Gene therapy for Parkinson's disease: determining the genes necessary for optimal dopamine replacement in rat models.

Kang UJ, Lee WY, Chang JW.

Hum Cell. 2001 Mar;14(1):39-48. Review.

PMID:
11436352
[PubMed - indexed for MEDLINE]
20.

Brain transplantation of neural stem cells cotransduced with tyrosine hydroxylase and GTP cyclohydrolase 1 in Parkinsonian rats.

Ryu MY, Lee MA, Ahn YH, Kim KS, Yoon SH, Snyder EY, Cho KG, Kim SU.

Cell Transplant. 2005;14(4):193-202.

PMID:
15929554
[PubMed - indexed for MEDLINE]

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