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Results: 1 to 20 of 145

1.

CD4 phosphorylation partially reverses Nef down-regulation of CD4.

Jin YJ, Zhang X, Boursiquot JG, Burakoff SJ.

J Immunol. 2004 Nov 1;173(9):5495-500.

PMID:
15494497
[PubMed - indexed for MEDLINE]
Free Article
2.
3.
4.

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef.

Garcia JV, Miller AD.

Nature. 1991 Apr 11;350(6318):508-11.

PMID:
2014052
[PubMed - indexed for MEDLINE]
5.

HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent.

Jin YJ, Cai CY, Zhang X, Zhang HT, Hirst JA, Burakoff SJ.

J Immunol. 2005 Sep 1;175(5):3157-64. Erratum in: J Immunol. 2006 Feb 15;176(4):2669.

PMID:
16116206
[PubMed - indexed for MEDLINE]
Free Article
6.

Molecular analysis of the cytoplasmic domain of CD4: overlapping but noncompetitive requirement for lck association and down-regulation by Nef.

Gratton S, Yao XJ, Venkatesan S, Cohen EA, Sékaly RP.

J Immunol. 1996 Oct 15;157(8):3305-11.

PMID:
8871625
[PubMed - indexed for MEDLINE]
7.

The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef.

Anderson SJ, Lenburg M, Landau NR, Garcia JV.

J Virol. 1994 May;68(5):3092-101. Erratum in: J Virol 1994 Jul;68(7):4705.

PMID:
8151774
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Lysine 144, a ubiquitin attachment site in HIV-1 Nef, is required for Nef-mediated CD4 down-regulation.

Jin YJ, Cai CY, Zhang X, Burakoff SJ.

J Immunol. 2008 Jun 15;180(12):7878-86.

PMID:
18523251
[PubMed - indexed for MEDLINE]
Free Article
9.

CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms.

Rose JJ, Janvier K, Chandrasekhar S, Sekaly RP, Bonifacino JS, Venkatesan S.

J Biol Chem. 2005 Mar 4;280(9):7413-26. Epub 2004 Dec 16.

PMID:
15611114
[PubMed - indexed for MEDLINE]
Free Article
10.
11.

Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation.

Greenberg ME, Bronson S, Lock M, Neumann M, Pavlakis GN, Skowronski J.

EMBO J. 1997 Dec 1;16(23):6964-76.

PMID:
9384576
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Modulation of specific surface receptors and activation sensitization in primary resting CD4+ T lymphocytes by the Nef protein of HIV-1.

Keppler OT, Tibroni N, Venzke S, Rauch S, Fackler OT.

J Leukoc Biol. 2006 Mar;79(3):616-27. Epub 2005 Dec 19.

PMID:
16365153
[PubMed - indexed for MEDLINE]
Free Article
13.

HIV-1 Nef protein downregulation of CD4 surface expression: relevance of the lck binding domain of CD4.

Bandres JC, Shaw AS, Ratner L.

Virology. 1995 Feb 20;207(1):338-41.

PMID:
7871751
[PubMed - indexed for MEDLINE]
Free Article
14.

Enhanced CD4 down-modulation by late stage HIV-1 nef alleles is associated with increased Env incorporation and viral replication.

Argañaraz ER, Schindler M, Kirchhoff F, Cortes MJ, Lama J.

J Biol Chem. 2003 Sep 5;278(36):33912-9. Epub 2003 Jun 19.

PMID:
12816953
[PubMed - indexed for MEDLINE]
Free Article
15.

Nef 27, but not the Nef 25 isoform of human immunodeficiency virus-type 1 pNL4.3 down-regulates surface CD4 and IL-2R expression in peripheral blood mononuclear cells and transformed T cells.

Greenway AL, McPhee DA, Grgacic E, Hewish D, Lucantoni A, Macreadie I, Azad A.

Virology. 1994 Jan;198(1):245-56.

PMID:
7903128
[PubMed - indexed for MEDLINE]
16.
17.

The conserved process of TCR/CD3 complex down-modulation by SIV Nef is mediated by the central core, not endocytic motifs.

Schaefer TM, Bell I, Pfeifer ME, Ghosh M, Trible RP, Fuller CL, Ashman C, Reinhart TA.

Virology. 2002 Oct 10;302(1):106-22.

PMID:
12429520
[PubMed - indexed for MEDLINE]
Free Article
18.

Virological importance of the protease-cleavage site in human immunodeficiency virus type 1 Nef is independent of both intravirion processing and CD4 down-regulation.

Pandori M, Craig H, Moutouh L, Corbeil J, Guatelli J.

Virology. 1998 Nov 25;251(2):302-16.

PMID:
9837795
[PubMed - indexed for MEDLINE]
Free Article
19.

Binding of HIV-1 Nef to a novel thioesterase enzyme correlates with Nef-mediated CD4 down-regulation.

Liu LX, Margottin F, Le Gall S, Schwartz O, Selig L, Benarous R, Benichou S.

J Biol Chem. 1997 May 23;272(21):13779-85.

PMID:
9153233
[PubMed - indexed for MEDLINE]
Free Article
20.

Vpu exerts a positive effect on HIV-1 infectivity by down-modulating CD4 receptor molecules at the surface of HIV-1-producing cells.

Levesque K, Zhao YS, Cohen EA.

J Biol Chem. 2003 Jul 25;278(30):28346-53. Epub 2003 May 13.

PMID:
12746459
[PubMed - indexed for MEDLINE]
Free Article

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