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Results: 1 to 20 of 73

1.

Phosphodiesterase inhibitors: a novel mechanism for receptor-independent antipsychotic medications.

Maxwell CR, Kanes SJ, Abel T, Siegel SJ.

Neuroscience. 2004;129(1):101-7.

PMID:
15489033
[PubMed - indexed for MEDLINE]
2.
3.

Rolipram: a specific phosphodiesterase 4 inhibitor with potential antipsychotic activity.

Kanes SJ, Tokarczyk J, Siegel SJ, Bilker W, Abel T, Kelly MP.

Neuroscience. 2007 Jan 5;144(1):239-46. Epub 2006 Nov 1.

PMID:
17081698
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Antipsychotic profile of rolipram: efficacy in rats and reduced sensitivity in mice deficient in the phosphodiesterase-4B (PDE4B) enzyme.

Siuciak JA, Chapin DS, McCarthy SA, Martin AN.

Psychopharmacology (Berl). 2007 Jun;192(3):415-24. Epub 2007 Mar 2.

PMID:
17333137
[PubMed - indexed for MEDLINE]
5.

Rolipram attenuates MK-801-induced deficits in latent inhibition.

Davis JA, Gould TJ.

Behav Neurosci. 2005 Apr;119(2):595-602.

PMID:
15839805
[PubMed - indexed for MEDLINE]
6.

A new model of the disrupted latent inhibition in C57BL/6J mice after bupropion treatment.

Lipina T, Roder J.

Psychopharmacology (Berl). 2010 Feb;208(3):487-98. doi: 10.1007/s00213-009-1749-3. Epub 2009 Dec 16.

PMID:
20013111
[PubMed - indexed for MEDLINE]
7.

Monoamine reuptake inhibition and nicotine receptor antagonism reduce amplitude and gating of auditory evoked potentials.

Siegel SJ, Maxwell CR, Majumdar S, Trief DF, Lerman C, Gur RE, Kanes SJ, Liang Y.

Neuroscience. 2005;133(3):729-38.

PMID:
15908134
[PubMed - indexed for MEDLINE]
8.

N-methyl-d-aspartic acid receptor antagonist-induced frequency oscillations in mice recreate pattern of electrophysiological deficits in schizophrenia.

Ehrlichman RS, Gandal MJ, Maxwell CR, Lazarewicz MT, Finkel LH, Contreras D, Turetsky BI, Siegel SJ.

Neuroscience. 2009 Jan 23;158(2):705-12. doi: 10.1016/j.neuroscience.2008.10.031. Epub 2008 Oct 28.

PMID:
19015010
[PubMed - indexed for MEDLINE]
9.

Effects of acute and chronic clozapine on D-amphetamine-induced disruption of auditory gating in the rat.

Joy B, McMahon RP, Shepard PD.

Psychopharmacology (Berl). 2004 Jul;174(2):274-82.

PMID:
14726994
[PubMed - indexed for MEDLINE]
10.

Mice expressing constitutively active Gsalpha exhibit stimulus encoding deficits similar to those observed in schizophrenia patients.

Maxwell CR, Liang Y, Kelly MP, Kanes SJ, Abel T, Siegel SJ.

Neuroscience. 2006 Sep 1;141(3):1257-64. Epub 2006 Jun 5.

PMID:
16750890
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

Dopamine receptor pharmacology: interactions with serotonin receptors and significance for the aetiology and treatment of schizophrenia.

Werkman TR, Glennon JC, Wadman WJ, McCreary AC.

CNS Neurol Disord Drug Targets. 2006 Feb;5(1):3-23. Review.

PMID:
16613551
[PubMed - indexed for MEDLINE]
13.

Phosphodiesterase 10A inhibitor activity in preclinical models of the positive, cognitive, and negative symptoms of schizophrenia.

Grauer SM, Pulito VL, Navarra RL, Kelly MP, Kelley C, Graf R, Langen B, Logue S, Brennan J, Jiang L, Charych E, Egerland U, Liu F, Marquis KL, Malamas M, Hage T, Comery TA, Brandon NJ.

J Pharmacol Exp Ther. 2009 Nov;331(2):574-90. doi: 10.1124/jpet.109.155994. Epub 2009 Aug 6.

PMID:
19661377
[PubMed - indexed for MEDLINE]
Free Article
14.

Preclinical investigations into the antipsychotic potential of the novel histamine H3 receptor antagonist GSK207040.

Southam E, Cilia J, Gartlon JE, Woolley ML, Lacroix LP, Jennings CA, Cluderay JE, Reavill C, Rourke C, Wilson DM, Dawson LA, Medhurst AD, Jones DN.

Psychopharmacology (Berl). 2009 Jan;201(4):483-94. doi: 10.1007/s00213-008-1310-9. Epub 2008 Sep 3.

PMID:
18762914
[PubMed - indexed for MEDLINE]
15.

Increasing synaptic noradrenaline, serotonin and histamine enhances in vivo binding of phosphodiesterase-4 inhibitor (R)-[11C]rolipram in rat brain, lung and heart.

Lourenco CM, Kenk M, Beanlands RS, DaSilva JN.

Life Sci. 2006 Jun 20;79(4):356-64. Epub 2006 Feb 24.

PMID:
16499932
[PubMed - indexed for MEDLINE]
16.

Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like activity.

Galici R, Boggs JD, Miller KL, Bonaventure P, Atack JR.

Behav Pharmacol. 2008 Mar;19(2):153-9. doi: 10.1097/FBP.0b013e3282f62d8c.

PMID:
18332680
[PubMed - indexed for MEDLINE]
17.

Phosphodiesterase 10A inhibitors: a novel approach to the treatment of the symptoms of schizophrenia.

Menniti FS, Chappie TA, Humphrey JM, Schmidt CJ.

Curr Opin Investig Drugs. 2007 Jan;8(1):54-9. Review.

PMID:
17263185
[PubMed - indexed for MEDLINE]
18.

The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity.

Woolley ML, Pemberton DJ, Bate S, Corti C, Jones DN.

Psychopharmacology (Berl). 2008 Feb;196(3):431-40. Epub 2007 Dec 5.

PMID:
18057917
[PubMed - indexed for MEDLINE]
19.

Interaction between the antidepressant-like behavioral effects of beta adrenergic agonists and the cyclic AMP PDE inhibitor rolipram in rats.

Zhang HT, Huang Y, Mishler K, Roerig SC, O'Donnell JM.

Psychopharmacology (Berl). 2005 Oct;182(1):104-15. Epub 2005 Sep 29.

PMID:
16010541
[PubMed - indexed for MEDLINE]
20.

Dopamine D2 receptor-dependent modulation of striatal NO synthase activity.

Sammut S, Bray KE, West AR.

Psychopharmacology (Berl). 2007 Apr;191(3):793-803. Epub 2007 Jan 6.

PMID:
17206493
[PubMed - indexed for MEDLINE]

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