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Items: 1 to 20 of 76


Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways.

Wu RC, Qin J, Yi P, Wong J, Tsai SY, Tsai MJ, O'Malley BW.

Mol Cell. 2004 Sep 24;15(6):937-49.


Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation.

Amazit L, Pasini L, Szafran AT, Berno V, Wu RC, Mielke M, Jones ED, Mancini MG, Hinojos CA, O'Malley BW, Mancini MA.

Mol Cell Biol. 2007 Oct;27(19):6913-32. Epub 2007 Jul 23.


Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.

Wu RC, Qin J, Hashimoto Y, Wong J, Xu J, Tsai SY, Tsai MJ, O'Malley BW.

Mol Cell Biol. 2002 May;22(10):3549-61.


Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence.

Unni E, Sun S, Nan B, McPhaul MJ, Cheskis B, Mancini MA, Marcelli M.

Cancer Res. 2004 Oct 1;64(19):7156-68.


Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator.

Labhart P, Karmakar S, Salicru EM, Egan BS, Alexiadis V, O'Malley BW, Smith CL.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1339-44. Epub 2005 Jan 26.


SRC-3/AIB1: transcriptional coactivator in oncogenesis.

Yan J, Tsai SY, Tsai MJ.

Acta Pharmacol Sin. 2006 Apr;27(4):387-94. Review.


SRC-3 is required for prostate cancer cell proliferation and survival.

Zhou HJ, Yan J, Luo W, Ayala G, Lin SH, Erdem H, Ittmann M, Tsai SY, Tsai MJ.

Cancer Res. 2005 Sep 1;65(17):7976-83.


Coordinated regulation of AIB1 transcriptional activity by sumoylation and phosphorylation.

Wu H, Sun L, Zhang Y, Chen Y, Shi B, Li R, Wang Y, Liang J, Fan D, Wu G, Wang D, Li S, Shang Y.

J Biol Chem. 2006 Aug 4;281(31):21848-56. Epub 2006 Jun 7.


Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1.

Liao L, Kuang SQ, Yuan Y, Gonzalez SM, O'Malley BW, Xu J.

J Steroid Biochem Mol Biol. 2002 Dec;83(1-5):3-14. Review.


Tyrosine phosphorylation of the nuclear receptor coactivator AIB1/SRC-3 is enhanced by Abl kinase and is required for its activity in cancer cells.

Oh AS, Lahusen JT, Chien CD, Fereshteh MP, Zhang X, Dakshanamurthy S, Xu J, Kagan BL, Wellstein A, Riegel AT.

Mol Cell Biol. 2008 Nov;28(21):6580-93. doi: 10.1128/MCB.00118-08. Epub 2008 Sep 2.


SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock.

Wu RC, Feng Q, Lonard DM, O'Malley BW.

Cell. 2007 Jun 15;129(6):1125-40.


The activity and stability of the transcriptional coactivator p/CIP/SRC-3 are regulated by CARM1-dependent methylation.

Naeem H, Cheng D, Zhao Q, Underhill C, Tini M, Bedford MT, Torchia J.

Mol Cell Biol. 2007 Jan;27(1):120-34. Epub 2006 Oct 16.


Steroid receptor coactivator-3, a homolog of Taiman that controls cell migration in the Drosophila ovary, regulates migration of human ovarian cancer cells.

Yoshida H, Liu J, Samuel S, Cheng W, Rosen D, Naora H.

Mol Cell Endocrinol. 2005 Dec 21;245(1-2):77-85. Epub 2005 Nov 18.

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