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Items: 1 to 20 of 109

1.

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

Manalo DJ, Rowan A, Lavoie T, Natarajan L, Kelly BD, Ye SQ, Garcia JG, Semenza GL.

Blood. 2005 Jan 15;105(2):659-69. Epub 2004 Sep 16.

2.

Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors.

Yamakawa M, Liu LX, Date T, Belanger AJ, Vincent KA, Akita GY, Kuriyama T, Cheng SH, Gregory RJ, Jiang C.

Circ Res. 2003 Oct 3;93(7):664-73. Epub 2003 Sep 4.

3.

Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1.

Kelly BD, Hackett SF, Hirota K, Oshima Y, Cai Z, Berg-Dixon S, Rowan A, Yan Z, Campochiaro PA, Semenza GL.

Circ Res. 2003 Nov 28;93(11):1074-81. Epub 2003 Oct 23.

4.

Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung.

Yu AY, Frid MG, Shimoda LA, Wiener CM, Stenmark K, Semenza GL.

Am J Physiol. 1998 Oct;275(4 Pt 1):L818-26.

6.

Transcriptional up-regulation of inhibitory PAS domain protein gene expression by hypoxia-inducible factor 1 (HIF-1): a negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells.

Makino Y, Uenishi R, Okamoto K, Isoe T, Hosono O, Tanaka H, Kanopka A, Poellinger L, Haneda M, Morimoto C.

J Biol Chem. 2007 May 11;282(19):14073-82. Epub 2007 Mar 12.

7.

Ca2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia.

Yuan G, Nanduri J, Bhasker CR, Semenza GL, Prabhakar NR.

J Biol Chem. 2005 Feb 11;280(6):4321-8. Epub 2004 Nov 29.

8.

Gene expression profiles in human cardiac cells subjected to hypoxia or expressing a hybrid form of HIF-1 alpha.

Jiang C, Lu H, Vincent KA, Shankara S, Belanger AJ, Cheng SH, Akita GY, Kelly RA, Goldberg MA, Gregory RJ.

Physiol Genomics. 2002 Feb 11;8(1):23-32.

PMID:
11842128
9.

Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1).

Greijer AE, van der Groep P, Kemming D, Shvarts A, Semenza GL, Meijer GA, van de Wiel MA, Belien JA, van Diest PJ, van der Wall E.

J Pathol. 2005 Jul;206(3):291-304.

PMID:
15906272
10.
11.

Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia.

Sowter HM, Raval RR, Moore JW, Ratcliffe PJ, Harris AL.

Cancer Res. 2003 Oct 1;63(19):6130-4. Erratum in: Cancer Res. 2003 Dec 1;63(23):8562.

12.

Harnessing the response to tissue hypoxia: HIF-1 alpha and therapeutic angiogenesis.

Vincent KA, Feron O, Kelly RA.

Trends Cardiovasc Med. 2002 Nov;12(8):362-7. Review.

PMID:
12536123
13.

Fasudil-induced hypoxia-inducible factor-1alpha degradation disrupts a hypoxia-driven vascular endothelial growth factor autocrine mechanism in endothelial cells.

Takata K, Morishige K, Takahashi T, Hashimoto K, Tsutsumi S, Yin L, Ohta T, Kawagoe J, Takahashi K, Kurachi H.

Mol Cancer Ther. 2008 Jun;7(6):1551-61. doi: 10.1158/1535-7163.MCT-07-0428.

14.

Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells.

Hu CJ, Iyer S, Sataur A, Covello KL, Chodosh LA, Simon MC.

Mol Cell Biol. 2006 May;26(9):3514-26.

15.

Constitutively active HIF-1alpha improves perfusion and arterial remodeling in an endovascular model of limb ischemia.

Patel TH, Kimura H, Weiss CR, Semenza GL, Hofmann LV.

Cardiovasc Res. 2005 Oct 1;68(1):144-54.

16.

Hypoxia and hypoxia-inducible factor-1alpha promote growth factor-induced proliferation of human vascular smooth muscle cells.

Schultz K, Fanburg BL, Beasley D.

Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2528-34. Epub 2006 Jan 6.

17.

Hypoxia inducible factor pathways as targets for functional foods.

Losso JN, Bawadi HA.

J Agric Food Chem. 2005 May 18;53(10):3751-68. Review.

PMID:
15884793
19.

Stabilization of hypoxia-inducible factor-1{alpha} by prostacyclin under prolonged hypoxia via reducing reactive oxygen species level in endothelial cells.

Chang TC, Huang CJ, Tam K, Chen SF, Tan KT, Tsai MS, Lin TN, Shyue SK.

J Biol Chem. 2005 Nov 4;280(44):36567-74. Epub 2005 Aug 22.

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