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Items: 1 to 20 of 104


Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton.

Audhya A, Loewith R, Parsons AB, Gao L, Tabuchi M, Zhou H, Boone C, Hall MN, Emr SD.

EMBO J. 2004 Oct 1;23(19):3747-57. Epub 2004 Sep 16.


The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation.

Tabuchi M, Audhya A, Parsons AB, Boone C, Emr SD.

Mol Cell Biol. 2006 Aug;26(15):5861-75.


The yeast PH domain proteins Slm1 and Slm2 are targets of sphingolipid signaling during the response to heat stress.

Daquinag A, Fadri M, Jung SY, Qin J, Kunz J.

Mol Cell Biol. 2007 Jan;27(2):633-50. Epub 2006 Nov 13.


Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization.

Kamada Y, Fujioka Y, Suzuki NN, Inagaki F, Wullschleger S, Loewith R, Hall MN, Ohsumi Y.

Mol Cell Biol. 2005 Aug;25(16):7239-48.


Mutual antagonism of target of rapamycin and calcineurin signaling.

Mulet JM, Martin DE, Loewith R, Hall MN.

J Biol Chem. 2006 Nov 3;281(44):33000-7. Epub 2006 Sep 7.


Calmodulin controls organization of the actin cytoskeleton via regulation of phosphatidylinositol (4,5)-bisphosphate synthesis in Saccharomyces cerevisiae.

Desrivières S, Cooke FT, Morales-Johansson H, Parker PJ, Hall MN.

Biochem J. 2002 Sep 15;366(Pt 3):945-51.


Plasma membrane proteins Slm1 and Slm2 mediate activation of the AGC kinase Ypk1 by TORC2 and sphingolipids in S. cerevisiae.

Niles BJ, Powers T.

Cell Cycle. 2012 Oct 15;11(20):3745-9. doi: 10.4161/cc.21752. Epub 2012 Aug 16.


Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease.

Bultynck G, Heath VL, Majeed AP, Galan JM, Haguenauer-Tsapis R, Cyert MS.

Mol Cell Biol. 2006 Jun;26(12):4729-45.


TOR2 is required for organization of the actin cytoskeleton in yeast.

Schmidt A, Kunz J, Hall MN.

Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13780-5.


TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae.

Pracheil T, Thornton J, Liu Z.

Genetics. 2012 Apr;190(4):1325-39. doi: 10.1534/genetics.111.138305. Epub 2012 Jan 31.


Plasma membrane recruitment and activation of the AGC kinase Ypk1 is mediated by target of rapamycin complex 2 (TORC2) and its effector proteins Slm1 and Slm2.

Niles BJ, Mogri H, Hill A, Vlahakis A, Powers T.

Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1536-41. doi: 10.1073/pnas.1117563109. Epub 2012 Jan 17.


Phosphatidylinositol phosphate kinases put PI4,5P(2) in its place.

Doughman RL, Firestone AJ, Anderson RA.

J Membr Biol. 2003 Jul 15;194(2):77-89. Review.

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