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Results: 1 to 20 of 170

1.

Hepsin promotes prostate cancer progression and metastasis.

Klezovitch O, Chevillet J, Mirosevich J, Roberts RL, Matusik RJ, Vasioukhin V.

Cancer Cell. 2004 Aug;6(2):185-95.

PMID:
15324701
[PubMed - indexed for MEDLINE]
Free Article
2.

Hepsin paradox reveals unexpected complexity of metastatic process.

Vasioukhin V.

Cell Cycle. 2004 Nov;3(11):1394-7. Epub 2004 Nov 28.

PMID:
15539945
[PubMed - indexed for MEDLINE]
Free Article
3.

Hepsin and prostate cancer.

Wu Q, Parry G.

Front Biosci. 2007 Sep 1;12:5052-9. Review.

PMID:
17569629
[PubMed - indexed for MEDLINE]
4.

Laminin-332 is a substrate for hepsin, a protease associated with prostate cancer progression.

Tripathi M, Nandana S, Yamashita H, Ganesan R, Kirchhofer D, Quaranta V.

J Biol Chem. 2008 Nov 7;283(45):30576-84. doi: 10.1074/jbc.M802312200. Epub 2008 Sep 9.

PMID:
18784072
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Pegylated kunitz domain inhibitor suppresses hepsin-mediated invasive tumor growth and metastasis.

Li W, Wang BE, Moran P, Lipari T, Ganesan R, Corpuz R, Ludlam MJ, Gogineni A, Koeppen H, Bunting S, Gao WQ, Kirchhofer D.

Cancer Res. 2009 Nov 1;69(21):8395-402. doi: 10.1158/0008-5472.CAN-09-1995. Epub 2009 Oct 20.

PMID:
19843851
[PubMed - indexed for MEDLINE]
Free Article
6.

Hepsin cooperates with MYC in the progression of adenocarcinoma in a prostate cancer mouse model.

Nandana S, Ellwood-Yen K, Sawyers C, Wills M, Weidow B, Case T, Vasioukhin V, Matusik R.

Prostate. 2010 May 1;70(6):591-600. doi: 10.1002/pros.21093.

PMID:
19938013
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice.

Williams TM, Hassan GS, Li J, Cohen AW, Medina F, Frank PG, Pestell RG, Di Vizio D, Loda M, Lisanti MP.

J Biol Chem. 2005 Jul 1;280(26):25134-45. Epub 2005 Mar 30.

PMID:
15802273
[PubMed - indexed for MEDLINE]
Free Article
8.

Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture.

Xuan JA, Schneider D, Toy P, Lin R, Newton A, Zhu Y, Finster S, Vogel D, Mintzer B, Dinter H, Light D, Parry R, Polokoff M, Whitlow M, Wu Q, Parry G.

Cancer Res. 2006 Apr 1;66(7):3611-9.

PMID:
16585186
[PubMed - indexed for MEDLINE]
Free Article
9.

Pro-urokinase-type plasminogen activator is a substrate for hepsin.

Moran P, Li W, Fan B, Vij R, Eigenbrot C, Kirchhofer D.

J Biol Chem. 2006 Oct 13;281(41):30439-46. Epub 2006 Aug 14.

PMID:
16908524
[PubMed - indexed for MEDLINE]
Free Article
10.

Expression profiling reveals hepsin overexpression in prostate cancer.

Magee JA, Araki T, Patil S, Ehrig T, True L, Humphrey PA, Catalona WJ, Watson MA, Milbrandt J.

Cancer Res. 2001 Aug 1;61(15):5692-6.

PMID:
11479199
[PubMed - indexed for MEDLINE]
Free Article
11.

KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis.

Narla G, DiFeo A, Fernandez Y, Dhanasekaran S, Huang F, Sangodkar J, Hod E, Leake D, Friedman SL, Hall SJ, Chinnaiyan AM, Gerald WL, Rubin MA, Martignetti JA.

J Clin Invest. 2008 Aug;118(8):2711-21. doi: 10.1172/JCI34780.

PMID:
18596922
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Matrix-dependent regulation of AKT in Hepsin-overexpressing PC3 prostate cancer cells.

Wittig-Blaich SM, Kacprzyk LA, Eismann T, Bewerunge-Hudler M, Kruse P, Winkler E, Strauss WS, Hibst R, Steiner R, Schrader M, Mertens D, Sültmann H, Wittig R.

Neoplasia. 2011 Jul;13(7):579-89.

PMID:
21750652
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma.

Lucas JM, True L, Hawley S, Matsumura M, Morrissey C, Vessella R, Nelson PS.

J Pathol. 2008 Jun;215(2):118-25. doi: 10.1002/path.2330.

PMID:
18338334
[PubMed - indexed for MEDLINE]
14.

Hepsin and maspin are inversely expressed in laser capture microdissectioned prostate cancer.

Chen Z, Fan Z, McNeal JE, Nolley R, Caldwell MC, Mahadevappa M, Zhang Z, Warrington JA, Stamey TA.

J Urol. 2003 Apr;169(4):1316-9.

PMID:
12629351
[PubMed - indexed for MEDLINE]
15.

Evolution of the androgen receptor pathway during progression of prostate cancer.

Hendriksen PJ, Dits NF, Kokame K, Veldhoven A, van Weerden WM, Bangma CH, Trapman J, Jenster G.

Cancer Res. 2006 May 15;66(10):5012-20.

PMID:
16707422
[PubMed - indexed for MEDLINE]
Free Article
16.

HEPSIN inhibits cell growth/invasion in prostate cancer cells.

Srikantan V, Valladares M, Rhim JS, Moul JW, Srivastava S.

Cancer Res. 2002 Dec 1;62(23):6812-6.

PMID:
12460890
[PubMed - indexed for MEDLINE]
Free Article
17.

Smad3 is overexpressed in advanced human prostate cancer and necessary for progressive growth of prostate cancer cells in nude mice.

Lu S, Lee J, Revelo M, Wang X, Lu S, Dong Z.

Clin Cancer Res. 2007 Oct 1;13(19):5692-702.

PMID:
17908958
[PubMed - indexed for MEDLINE]
Free Article
18.

Neuroendocrine differentiation in the 12T-10 transgenic prostate mouse model mimics endocrine differentiation of pancreatic beta cells.

Gupta A, Wang Y, Browne C, Kim S, Case T, Paul M, Wills ML, Matusik RJ.

Prostate. 2008 Jan 1;68(1):50-60.

PMID:
18004726
[PubMed - indexed for MEDLINE]
19.

Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse model.

Hsieh CL, Xie Z, Yu J, Martin WD, Datta MW, Wu GJ, Chung LW.

Prostate. 2007 May 15;67(7):685-91.

PMID:
17342752
[PubMed - indexed for MEDLINE]
20.

Essential role for activation of the Polycomb group (PcG) protein chromatin silencing pathway in metastatic prostate cancer.

Berezovska OP, Glinskii AB, Yang Z, Li XM, Hoffman RM, Glinsky GV.

Cell Cycle. 2006 Aug;5(16):1886-901. Epub 2006 Aug 15.

PMID:
16963837
[PubMed - indexed for MEDLINE]
Free Article

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