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Results: 1 to 20 of 98

1.

Ionic interactions near the loop L4 are important for maintaining the active-site environment and the dimer stability of (pro)caspase 3.

Feeney B, Pop C, Tripathy A, Clark AC.

Biochem J. 2004 Dec 15;384(Pt 3):515-25.

PMID:
15312047
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Mutations in the procaspase-3 dimer interface affect the activity of the zymogen.

Pop C, Feeney B, Tripathy A, Clark AC.

Biochemistry. 2003 Oct 28;42(42):12311-20.

PMID:
14567692
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

An uncleavable procaspase-3 mutant has a lower catalytic efficiency but an active site similar to that of mature caspase-3.

Bose K, Pop C, Feeney B, Clark AC.

Biochemistry. 2003 Oct 28;42(42):12298-310.

PMID:
14567691
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Removal of the pro-domain does not affect the conformation of the procaspase-3 dimer.

Pop C, Chen YR, Smith B, Bose K, Bobay B, Tripathy A, Franzen S, Clark AC.

Biochemistry. 2001 Nov 27;40(47):14224-35.

PMID:
11714276
[PubMed - indexed for MEDLINE]
5.

Kinetic comparison of procaspase-3 and caspase-3.

Karki P, Lee J, Shin SY, Cho B, Park IS.

Arch Biochem Biophys. 2005 Oct 1;442(1):125-32.

PMID:
16140256
[PubMed - indexed for MEDLINE]
6.

Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3.

Walters J, Swartz P, Mattos C, Clark AC.

Arch Biochem Biophys. 2011 Apr 1;508(1):31-8. doi: 10.1016/j.abb.2011.01.011. Epub 2011 Jan 23.

PMID:
21266160
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The structure of procaspase 6 is similar to that of active mature caspase 6.

Kang BH, Ko E, Kwon OK, Choi KY.

Biochem J. 2002 Jun 15;364(Pt 3):629-34.

PMID:
12049625
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Molecular dynamics simulations of structural changes during procaspase 3 activation.

Piana S, Rothlisberger U.

Proteins. 2004 Jun 1;55(4):932-41.

PMID:
15146491
[PubMed - indexed for MEDLINE]
9.

Role of loop bundle hydrogen bonds in the maturation and activity of (Pro)caspase-3.

Feeney B, Pop C, Swartz P, Mattos C, Clark AC.

Biochemistry. 2006 Nov 7;45(44):13249-63.

PMID:
17073446
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

pH effects on the stability and dimerization of procaspase-3.

Bose K, Clark AC.

Protein Sci. 2005 Jan;14(1):24-36. Epub 2004 Dec 2.

PMID:
15576551
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding.

Chai J, Wu Q, Shiozaki E, Srinivasula SM, Alnemri ES, Shi Y.

Cell. 2001 Nov 2;107(3):399-407.

PMID:
11701129
[PubMed - indexed for MEDLINE]
Free Article
12.

Dimeric procaspase-3 unfolds via a four-state equilibrium process.

Bose K, Clark AC.

Biochemistry. 2001 Nov 27;40(47):14236-42.

PMID:
11714277
[PubMed - indexed for MEDLINE]
13.

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1.

Qin H, Srinivasula SM, Wu G, Fernandes-Alnemri T, Alnemri ES, Shi Y.

Nature. 1999 Jun 10;399(6736):549-57.

PMID:
10376594
[PubMed - indexed for MEDLINE]
14.

Interdimer processing mechanism of procaspase-8 activation.

Chang DW, Xing Z, Capacio VL, Peter ME, Yang X.

EMBO J. 2003 Aug 15;22(16):4132-42.

PMID:
12912912
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Reassembly of active caspase-3 is facilitated by the propeptide.

Feeney B, Clark AC.

J Biol Chem. 2005 Dec 2;280(48):39772-85. Epub 2005 Oct 3.

PMID:
16203739
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The structural basis for the perturbed pKa of the catalytic base in 4-oxalocrotonate tautomerase: kinetic and structural effects of mutations of Phe-50.

Czerwinski RM, Harris TK, Massiah MA, Mildvan AS, Whitman CP.

Biochemistry. 2001 Feb 20;40(7):1984-95.

PMID:
11329265
[PubMed - indexed for MEDLINE]
17.

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization.

Srinivasula SM, Ahmad M, Fernandes-Alnemri T, Alnemri ES.

Mol Cell. 1998 Jun;1(7):949-57.

PMID:
9651578
[PubMed - indexed for MEDLINE]
Free Article
18.

Rearrangement of tryptophan residues in caspase-3 active site upon activation.

Park IS, Moon HR, Seok H, Lee M.

Biochim Biophys Acta. 2004 Jul 1;1700(1):5-9.

PMID:
15210119
[PubMed - indexed for MEDLINE]
Free Article
19.

Structural and biochemical studies on procaspase-8: new insights on initiator caspase activation.

Keller N, Mares J, Zerbe O, Grütter MG.

Structure. 2009 Mar 11;17(3):438-48. doi: 10.1016/j.str.2008.12.019.

PMID:
19278658
[PubMed - indexed for MEDLINE]
Free Article
20.

Effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase on the pKa values of active site residues and on the pH dependence of catalysis.

Czerwinski RM, Harris TK, Johnson WH Jr, Legler PM, Stivers JT, Mildvan AS, Whitman CP.

Biochemistry. 1999 Sep 21;38(38):12358-66.

PMID:
10493803
[PubMed - indexed for MEDLINE]

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