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Results: 1 to 20 of 625

1.

Acyl-CoA carboxylases (accD2 and accD3), together with a unique polyketide synthase (Cg-pks), are key to mycolic acid biosynthesis in Corynebacterianeae such as Corynebacterium glutamicum and Mycobacterium tuberculosis.

Gande R, Gibson KJ, Brown AK, Krumbach K, Dover LG, Sahm H, Shioyama S, Oikawa T, Besra GS, Eggeling L.

J Biol Chem. 2004 Oct 22;279(43):44847-57. Epub 2004 Aug 11.

PMID:
15308633
[PubMed - indexed for MEDLINE]
Free Article
2.

The two carboxylases of Corynebacterium glutamicum essential for fatty acid and mycolic acid synthesis.

Gande R, Dover LG, Krumbach K, Besra GS, Sahm H, Oikawa T, Eggeling L.

J Bacteriol. 2007 Jul;189(14):5257-64. Epub 2007 May 4.

PMID:
17483212
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The acyl-AMP ligase FadD32 and AccD4-containing acyl-CoA carboxylase are required for the synthesis of mycolic acids and essential for mycobacterial growth: identification of the carboxylation product and determination of the acyl-CoA carboxylase components.

Portevin D, de Sousa-D'Auria C, Montrozier H, Houssin C, Stella A, Lanéelle MA, Bardou F, Guilhot C, Daffé M.

J Biol Chem. 2005 Mar 11;280(10):8862-74. Epub 2005 Jan 4.

PMID:
15632194
[PubMed - indexed for MEDLINE]
Free Article
4.

Deletion of Cg-emb in corynebacterianeae leads to a novel truncated cell wall arabinogalactan, whereas inactivation of Cg-ubiA results in an arabinan-deficient mutant with a cell wall galactan core.

Alderwick LJ, Radmacher E, Seidel M, Gande R, Hitchen PG, Morris HR, Dell A, Sahm H, Eggeling L, Besra GS.

J Biol Chem. 2005 Sep 16;280(37):32362-71. Epub 2005 Jul 21.

PMID:
16040600
[PubMed - indexed for MEDLINE]
Free Article
5.

The reductase that catalyzes mycolic motif synthesis is required for efficient attachment of mycolic acids to arabinogalactan.

Lea-Smith DJ, Pyke JS, Tull D, McConville MJ, Coppel RL, Crellin PK.

J Biol Chem. 2007 Apr 13;282(15):11000-8. Epub 2007 Feb 17.

PMID:
17308303
[PubMed - indexed for MEDLINE]
Free Article
6.

AccD6, a member of the Fas II locus, is a functional carboxyltransferase subunit of the acyl-coenzyme A carboxylase in Mycobacterium tuberculosis.

Daniel J, Oh TJ, Lee CM, Kolattukudy PE.

J Bacteriol. 2007 Feb;189(3):911-7. Epub 2006 Nov 17.

PMID:
17114269
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB.

Schaeffer ML, Agnihotri G, Volker C, Kallender H, Brennan PJ, Lonsdale JT.

J Biol Chem. 2001 Dec 14;276(50):47029-37. Epub 2001 Oct 12.

PMID:
11600501
[PubMed - indexed for MEDLINE]
Free Article
8.

Two functional FAS-I type fatty acid synthases in Corynebacterium glutamicum.

Radmacher E, Alderwick LJ, Besra GS, Brown AK, Gibson KJ, Sahm H, Eggeling L.

Microbiology. 2005 Jul;151(Pt 7):2421-7.

PMID:
16000732
[PubMed - indexed for MEDLINE]
Free Article
9.

The crucial role of trehalose and structurally related oligosaccharides in the biosynthesis and transfer of mycolic acids in Corynebacterineae.

Tropis M, Meniche X, Wolf A, Gebhardt H, Strelkov S, Chami M, Schomburg D, Krämer R, Morbach S, Daffé M.

J Biol Chem. 2005 Jul 15;280(28):26573-85. Epub 2005 May 18.

PMID:
15901732
[PubMed - indexed for MEDLINE]
Free Article
10.

The TetR-type transcriptional regulator FasR of Corynebacterium glutamicum controls genes of lipid synthesis during growth on acetate.

Nickel J, Irzik K, van Ooyen J, Eggeling L.

Mol Microbiol. 2010 Oct;78(1):253-65. doi: 10.1111/j.1365-2958.2010.07337.x.

PMID:
20923423
[PubMed - indexed for MEDLINE]
11.

Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II.

Kremer L, Nampoothiri KM, Lesjean S, Dover LG, Graham S, Betts J, Brennan PJ, Minnikin DE, Locht C, Besra GS.

J Biol Chem. 2001 Jul 27;276(30):27967-74. Epub 2001 May 23.

PMID:
11373295
[PubMed - indexed for MEDLINE]
Free Article
12.

ACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteria.

Kurth DG, Gago GM, de la Iglesia A, Bazet Lyonnet B, Lin TW, Morbidoni HR, Tsai SC, Gramajo H.

Microbiology. 2009 Aug;155(Pt 8):2664-75. doi: 10.1099/mic.0.027714-0. Epub 2009 May 7.

PMID:
19423629
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III.

Scarsdale JN, Kazanina G, He X, Reynolds KA, Wright HT.

J Biol Chem. 2001 Jun 8;276(23):20516-22. Epub 2001 Mar 8.

PMID:
11278743
[PubMed - indexed for MEDLINE]
Free Article
14.

The Pks13/FadD32 crosstalk for the biosynthesis of mycolic acids in Mycobacterium tuberculosis.

Gavalda S, Léger M, van der Rest B, Stella A, Bardou F, Montrozier H, Chalut C, Burlet-Schiltz O, Marrakchi H, Daffé M, Quémard A.

J Biol Chem. 2009 Jul 17;284(29):19255-64. doi: 10.1074/jbc.M109.006940. Epub 2009 May 12.

PMID:
19436070
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Identification of a novel arabinofuranosyltransferase AftB involved in a terminal step of cell wall arabinan biosynthesis in Corynebacterianeae, such as Corynebacterium glutamicum and Mycobacterium tuberculosis.

Seidel M, Alderwick LJ, Birch HL, Sahm H, Eggeling L, Besra GS.

J Biol Chem. 2007 May 18;282(20):14729-40. Epub 2007 Mar 26.

PMID:
17387176
[PubMed - indexed for MEDLINE]
Free Article
16.

Characterization of the in vivo acceptors of the mycoloyl residues transferred by the corynebacterial PS1 and the related mycobacterial antigens 85.

Puech V, Bayan N, Salim K, Leblon G, Daffé M.

Mol Microbiol. 2000 Mar;35(5):1026-41.

PMID:
10712685
[PubMed - indexed for MEDLINE]
17.

Drugs that inhibit mycolic acid biosynthesis in Mycobacterium tuberculosis.

Schroeder EK, de Souza N, Santos DS, Blanchard JS, Basso LA.

Curr Pharm Biotechnol. 2002 Sep;3(3):197-225. Review.

PMID:
12164478
[PubMed - indexed for MEDLINE]
18.

Evolutionary implications of bacterial polyketide synthases.

Jenke-Kodama H, Sandmann A, Müller R, Dittmann E.

Mol Biol Evol. 2005 Oct;22(10):2027-39. Epub 2005 Jun 15.

PMID:
15958783
[PubMed - indexed for MEDLINE]
Free Article
19.

Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis.

Slayden RA, Lee RE, Armour JW, Cooper AM, Orme IM, Brennan PJ, Besra GS.

Antimicrob Agents Chemother. 1996 Dec;40(12):2813-9.

PMID:
9124847
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The key role of the mycolic acid content in the functionality of the cell wall permeability barrier in Corynebacterineae.

Gebhardt H, Meniche X, Tropis M, Krämer R, Daffé M, Morbach S.

Microbiology. 2007 May;153(Pt 5):1424-34.

PMID:
17464056
[PubMed - indexed for MEDLINE]
Free Article

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