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Items: 1 to 20 of 95

1.

Opioid-induced respiratory depression: are 5-HT4a receptor agonists the cure?

Eilers H, Schumacher MA.

Mol Interv. 2004 Aug;4(4):197-9. No abstract available.

PMID:
15304555
2.

mu-Opioid/5-HT4 dual pharmacologically active agents-efforts towards an effective opioid analgesic with less GI and respiratory side effects (Part I).

Shao L, Wang F, Hewitt MC, Barberich TJ.

Bioorg Med Chem Lett. 2009 Oct 1;19(19):5679-83. doi: 10.1016/j.bmcl.2009.08.016. Epub 2009 Aug 8.

PMID:
19700325
3.

5-HT4(a) receptors avert opioid-induced breathing depression without loss of analgesia.

Manzke T, Guenther U, Ponimaskin EG, Haller M, Dutschmann M, Schwarzacher S, Richter DW.

Science. 2003 Jul 11;301(5630):226-9.

4.

The 5-hydroxytryptamine 4 receptor agonist mosapride does not antagonize morphine-induced respiratory depression.

Lötsch J, Skarke C, Schneider A, Hummel T, Geisslinger G.

Clin Pharmacol Ther. 2005 Sep;78(3):278-87.

PMID:
16153398
5.

Effect of chronic pain on morphine-induced respiratory depression in mice.

Kamei J, Ohsawa M, Hayashi SS, Nakanishi Y.

Neuroscience. 2011 Feb 3;174:224-33. doi: 10.1016/j.neuroscience.2010.11.012. Epub 2010 Nov 21.

PMID:
21081158
6.

Medicine. A sigh of relief for painkillers.

Couzin J.

Science. 2003 Jul 11;301(5630):150. No abstract available.

PMID:
12855777
7.

Polymorphism of mu-opioid receptor gene (OPRM1:c.118A>G) does not protect against opioid-induced respiratory depression despite reduced analgesic response.

Romberg RR, Olofsen E, Bijl H, Taschner PE, Teppema LJ, Sarton EY, van Kleef JW, Dahan A.

Anesthesiology. 2005 Mar;102(3):522-30.

PMID:
15731588
8.

Supranodose vagotomy eliminates respiratory depression evoked by dermorphin in anaesthetized rats.

Wojciechowski P, Szereda-Przestaszewska M, Lipkowski AW.

Eur J Pharmacol. 2007 Jun 1;563(1-3):209-12. Epub 2007 Feb 17.

PMID:
17362918
9.

Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750.

Becker DP, Flynn DL, Shone RL, Gullikson G.

Bioorg Med Chem Lett. 2004 Nov 15;14(22):5509-12.

PMID:
15482914
10.
11.

5-Hydroxytryptamine 1A/7 and 4alpha receptors differentially prevent opioid-induced inhibition of brain stem cardiorespiratory function.

Wang X, Dergacheva O, Kamendi H, Gorini C, Mendelowitz D.

Hypertension. 2007 Aug;50(2):368-76. Epub 2007 Jun 18.

12.

Opioid-induced depression in the lamprey respiratory network.

Mutolo D, Bongianni F, Einum J, Dubuc R, Pantaleo T.

Neuroscience. 2007 Dec 12;150(3):720-9. Epub 2007 Sep 20.

PMID:
17949922
13.

5-HT4 receptor and Alzheimer's disease: the amyloid connection.

Lezoualc'h F.

Exp Neurol. 2007 Jun;205(2):325-9. Epub 2007 Feb 9. Review. No abstract available.

PMID:
17346704
14.

Serotonin(4) (5-HT(4)) receptor agonists are putative antidepressants with a rapid onset of action.

Lucas G, Rymar VV, Du J, Mnie-Filali O, Bisgaard C, Manta S, Lambas-Senas L, Wiborg O, Haddjeri N, Piñeyro G, Sadikot AF, Debonnel G.

Neuron. 2007 Sep 6;55(5):712-25.

15.

Optimization of a pharmacophore model for 5-HT4 agonists using CoMFA and receptor based alignment.

Iskander MN, Leung LM, Buley T, Ayad F, Di Iulio J, Tan YY, Coupar IM.

Eur J Med Chem. 2006 Jan;41(1):16-26. Epub 2005 Nov 15.

PMID:
16293350
16.

Reduced suppression of CO2-induced ventilatory stimulation by endomorphins relative to morphine.

Czapla MA, Zadina JE.

Brain Res. 2005 Oct 19;1059(2):159-66. Epub 2005 Oct 11.

PMID:
16223471
17.

New insights into serotonin 5-HT4 receptors : a novel therapeutic target for Alzheimer's disease?

Maillet M, Robert SJ, Lezoualc'h F.

Curr Alzheimer Res. 2004 May;1(2):79-85. Review.

PMID:
15975071
18.

Ontogeny of respiratory sensitivity and tolerance to the mu-opioid agonist fentanyl in rat.

Laferrière A, Colin-Durand J, Moss IR.

Brain Res Dev Brain Res. 2005 May 12;156(2):210-7.

PMID:
16099308
19.

Effects of mu-, delta- and kappa-opioid receptor agonists on methamphetamine-induced self-injurious behavior in mice.

Mori T, Ito S, Kita T, Narita M, Suzuki T, Sawaguchi T.

Eur J Pharmacol. 2006 Feb 17;532(1-2):81-7. Epub 2006 Feb 7.

PMID:
16464448
20.

5-HT4 receptor agonists: similar but not the same.

De Maeyer JH, Lefebvre RA, Schuurkes JA.

Neurogastroenterol Motil. 2008 Feb;20(2):99-112. doi: 10.1111/j.1365-2982.2007.01059.x. Review.

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