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Results: 1 to 20 of 131

1.

53BP1, an activator of ATM in response to DNA damage.

Mochan TA, Venere M, DiTullio RA Jr, Halazonetis TD.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):945-52.

PMID:
15279780
[PubMed - indexed for MEDLINE]
2.

53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage.

Mochan TA, Venere M, DiTullio RA Jr, Halazonetis TD.

Cancer Res. 2003 Dec 15;63(24):8586-91.

PMID:
14695167
[PubMed - indexed for MEDLINE]
Free Article
3.

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks.

Schultz LB, Chehab NH, Malikzay A, Halazonetis TD.

J Cell Biol. 2000 Dec 25;151(7):1381-90.

PMID:
11134068
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

ATM signaling and 53BP1.

Zgheib O, Huyen Y, DiTullio RA Jr, Snyder A, Venere M, Stavridi ES, Halazonetis TD.

Radiother Oncol. 2005 Aug;76(2):119-22. Review.

PMID:
16024119
[PubMed - indexed for MEDLINE]
5.

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.

Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A.

J Cell Sci. 2005 Apr 15;118(Pt 8):1629-39. Epub 2005 Mar 22.

PMID:
15784679
[PubMed - indexed for MEDLINE]
Free Article
6.

NFBD1/Mdc1 mediates ATR-dependent DNA damage response.

Peng A, Chen PL.

Cancer Res. 2005 Feb 15;65(4):1158-63.

PMID:
15734998
[PubMed - indexed for MEDLINE]
Free Article
7.

Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest.

Shibata A, Barton O, Noon AT, Dahm K, Deckbar D, Goodarzi AA, Löbrich M, Jeggo PA.

Mol Cell Biol. 2010 Jul;30(13):3371-83. doi: 10.1128/MCB.01644-09. Epub 2010 Apr 26.

PMID:
20421415
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Human PTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation.

Jowsey PA, Doherty AJ, Rouse J.

J Biol Chem. 2004 Dec 31;279(53):55562-9. Epub 2004 Sep 27.

PMID:
15456759
[PubMed - indexed for MEDLINE]
Free Article
9.

NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage.

Peng A, Chen PL.

J Biol Chem. 2003 Mar 14;278(11):8873-6. Epub 2003 Jan 24.

PMID:
12551934
[PubMed - indexed for MEDLINE]
Free Article
10.

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair.

Noon AT, Shibata A, Rief N, Löbrich M, Stewart GS, Jeggo PA, Goodarzi AA.

Nat Cell Biol. 2010 Feb;12(2):177-84. doi: 10.1038/ncb2017. Epub 2010 Jan 17.

PMID:
20081839
[PubMed - indexed for MEDLINE]
11.

Protein-protein interactions occur between p53 phosphoforms and ATM and 53BP1 at sites of exogenous DNA damage.

Al Rashid ST, Harding SM, Law C, Coackley C, Bristow RG.

Radiat Res. 2011 May;175(5):588-98. doi: 10.1667/RR2084.1. Epub 2011 Mar 1.

PMID:
21361779
[PubMed - indexed for MEDLINE]
12.

Boundaries and physical characterization of a new domain shared between mammalian 53BP1 and yeast Rad9 checkpoint proteins.

Alpha-Bazin B, Lorphelin A, Nozerand N, Charier G, Marchetti C, Bérenguer F, Couprie J, Gilquin B, Zinn-Justin S, Quéméneur E.

Protein Sci. 2005 Jul;14(7):1827-39.

PMID:
15987907
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

An investigation into 53BP1 complex formation.

Roche KC, Lowndes NF.

Adv Exp Med Biol. 2007;604:47-57.

PMID:
17695720
[PubMed - indexed for MEDLINE]
14.

53BP1 promotes ATM activity through direct interactions with the MRN complex.

Lee JH, Goodarzi AA, Jeggo PA, Paull TT.

EMBO J. 2010 Feb 3;29(3):574-85. doi: 10.1038/emboj.2009.372. Epub 2009 Dec 10.

PMID:
20010693
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer.

DiTullio RA Jr, Mochan TA, Venere M, Bartkova J, Sehested M, Bartek J, Halazonetis TD.

Nat Cell Biol. 2002 Dec;4(12):998-1002. Erratum in: Nat Cell Biol. 2003 Jan;5(1):84..

PMID:
12447382
[PubMed - indexed for MEDLINE]
16.

The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax.

Goodarzi AA, Jeggo P, Lobrich M.

DNA Repair (Amst). 2010 Dec 10;9(12):1273-82. doi: 10.1016/j.dnarep.2010.09.013. Epub 2010 Oct 30. Review.

PMID:
21036673
[PubMed - indexed for MEDLINE]
17.

Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks.

Sordet O, Redon CE, Guirouilh-Barbat J, Smith S, Solier S, Douarre C, Conti C, Nakamura AJ, Das BB, Nicolas E, Kohn KW, Bonner WM, Pommier Y.

EMBO Rep. 2009 Aug;10(8):887-93. doi: 10.1038/embor.2009.97. Epub 2009 Jun 26.

PMID:
19557000
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways.

Rappold I, Iwabuchi K, Date T, Chen J.

J Cell Biol. 2001 Apr 30;153(3):613-20. Erratum in: J Cell Biol 2001 Jul 23;154(2):469.

PMID:
11331310
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The ATM-mediated DNA-damage response: taking shape.

Shiloh Y.

Trends Biochem Sci. 2006 Jul;31(7):402-10. Epub 2006 Jun 13.

PMID:
16774833
[PubMed - indexed for MEDLINE]
20.

RNF8-dependent and RNF8-independent regulation of 53BP1 in response to DNA damage.

Sakasai R, Tibbetts R.

J Biol Chem. 2008 May 16;283(20):13549-55. doi: 10.1074/jbc.M710197200. Epub 2008 Mar 12.

PMID:
18337245
[PubMed - indexed for MEDLINE]
Free Article

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