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Similar articles for PubMed (Select 15252017)


The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers.

Szentpétery Z, Kern A, Liliom K, Sarkadi B, Váradi A, Bakos E.

J Biol Chem. 2004 Oct 1;279(40):41670-8. Epub 2004 Jul 12.


Nucleotides and transported substrates modulate different steps of the ATPase catalytic cycle of MRP1 multidrug transporter.

Kern A, Szentpétery Z, Liliom K, Bakos E, Sarkadi B, Váradi A.

Biochem J. 2004 Jun 1;380(Pt 2):549-60.


Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1).

Payen LF, Gao M, Westlake CJ, Cole SP, Deeley RG.

J Biol Chem. 2003 Oct 3;278(40):38537-47. Epub 2003 Jul 27.


The "LSGGQ" motif in each nucleotide-binding domain of human P-glycoprotein is adjacent to the opposing walker A sequence.

Loo TW, Bartlett MC, Clarke DM.

J Biol Chem. 2002 Nov 1;277(44):41303-6. Epub 2002 Sep 10.


Function of the ABC signature sequences in the human multidrug resistance protein 1.

Ren XQ, Furukawa T, Haraguchi M, Sumizawa T, Aoki S, Kobayashi M, Akiyama S.

Mol Pharmacol. 2004 Jun;65(6):1536-42.


Vanadate-catalyzed photocleavage of the signature motif of an ATP-binding cassette (ABC) transporter.

Fetsch EE, Davidson AL.

Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9685-90. Epub 2002 Jul 1.


Functional studies on the MRP1 multidrug transporter: characterization of ABC-signature mutant variants.

Szentpétery Z, Sarkadi B, Bakos E, Váradi A.

Anticancer Res. 2004 Mar-Apr;24(2A):449-55.


Role of glycine-534 and glycine-1179 of human multidrug resistance protein (MDR1) in drug-mediated control of ATP hydrolysis.

Szakács G, Ozvegy C, Bakos E, Sarkadi B, Váradi A.

Biochem J. 2001 May 15;356(Pt 1):71-5.


Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.

Létourneau IJ, Slot AJ, Deeley RG, Cole SP.

Drug Metab Dispos. 2007 Aug;35(8):1372-9. Epub 2007 May 9.


Molecular modeling correctly predicts the functional importance of Phe594 in transmembrane helix 11 of the multidrug resistance protein, MRP1 (ABCC1).

Campbell JD, Koike K, Moreau C, Sansom MS, Deeley RG, Cole SP.

J Biol Chem. 2004 Jan 2;279(1):463-8. Epub 2003 Oct 15.


The conserved glutamate residue adjacent to the Walker-B motif is the catalytic base for ATP hydrolysis in the ATP-binding cassette transporter BmrA.

Orelle C, Dalmas O, Gros P, Di Pietro A, Jault JM.

J Biol Chem. 2003 Nov 21;278(47):47002-8. Epub 2003 Sep 10.


Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter.

Létourneau IJ, Nakajima A, Deeley RG, Cole SP.

Biochem Pharmacol. 2008 Apr 15;75(8):1659-69. doi: 10.1016/j.bcp.2008.01.009. Epub 2008 Feb 5.

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