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Results: 1 to 20 of 428

1.

Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.

Anthony TG, McDaniel BJ, Byerley RL, McGrath BC, Cavener DR, McNurlan MA, Wek RC.

J Biol Chem. 2004 Aug 27;279(35):36553-61. Epub 2004 Jun 22.

PMID:
15213227
[PubMed - indexed for MEDLINE]
Free Article
2.

Oral administration of leucine stimulates phosphorylation of 4E-bP1 and S6K 1 in skeletal muscle but not in liver of diabetic rats.

Yoshizawa F, Hirayama S, Sekizawa H, Nagasawa T, Sugahara K.

J Nutr Sci Vitaminol (Tokyo). 2002 Feb;48(1):59-64.

PMID:
12026190
[PubMed - indexed for MEDLINE]
3.

Regulation of translation initiation by amino acids in eukaryotic cells.

Kimball SR.

Prog Mol Subcell Biol. 2001;26:155-84. Review.

PMID:
11575165
[PubMed - indexed for MEDLINE]
4.

Orally administered leucine enhances protein synthesis in skeletal muscle of diabetic rats in the absence of increases in 4E-BP1 or S6K1 phosphorylation.

Anthony JC, Reiter AK, Anthony TG, Crozier SJ, Lang CH, MacLean DA, Kimball SR, Jefferson LS.

Diabetes. 2002 Apr;51(4):928-36.

PMID:
11916909
[PubMed - indexed for MEDLINE]
Free Article
5.

Endotoxin disrupts the leucine-signaling pathway involving phosphorylation of mTOR, 4E-BP1, and S6K1 in skeletal muscle.

Lang CH, Frost RA.

J Cell Physiol. 2005 Apr;203(1):144-55.

PMID:
15389631
[PubMed - indexed for MEDLINE]
6.

Developmental regulation of the activation of signaling components leading to translation initiation in skeletal muscle of neonatal pigs.

Suryawan A, Escobar J, Frank JW, Nguyen HV, Davis TA.

Am J Physiol Endocrinol Metab. 2006 Oct;291(4):E849-59. Epub 2006 Jun 6.

PMID:
16757550
[PubMed - indexed for MEDLINE]
Free Article
7.

mTOR, AMPK, and GCN2 coordinate the adaptation of hepatic energy metabolic pathways in response to protein intake in the rat.

Chotechuang N, Azzout-Marniche D, Bos C, Chaumontet C, Gausserès N, Steiler T, Gaudichon C, Tomé D.

Am J Physiol Endocrinol Metab. 2009 Dec;297(6):E1313-23. doi: 10.1152/ajpendo.91000.2008. Epub 2009 Sep 8.

PMID:
19738034
[PubMed - indexed for MEDLINE]
Free Article
8.

Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway.

Anthony JC, Yoshizawa F, Anthony TG, Vary TC, Jefferson LS, Kimball SR.

J Nutr. 2000 Oct;130(10):2413-9.

PMID:
11015466
[PubMed - indexed for MEDLINE]
Free Article
9.

Deficiency of dietary EAA preferentially inhibits mRNA translation of ribosomal proteins in liver of meal-fed rats.

Anthony TG, Reiter AK, Anthony JC, Kimball SR, Jefferson LS.

Am J Physiol Endocrinol Metab. 2001 Sep;281(3):E430-9.

PMID:
11500297
[PubMed - indexed for MEDLINE]
Free Article
10.

Elevated plasma free fatty acids decrease basal protein synthesis, but not the anabolic effect of leucine, in skeletal muscle.

Lang CH.

Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E666-74. Epub 2006 May 9.

PMID:
16684854
[PubMed - indexed for MEDLINE]
Free Article
11.

Alcohol impairs leucine-mediated phosphorylation of 4E-BP1, S6K1, eIF4G, and mTOR in skeletal muscle.

Lang CH, Frost RA, Deshpande N, Kumar V, Vary TC, Jefferson LS, Kimball SR.

Am J Physiol Endocrinol Metab. 2003 Dec;285(6):E1205-15. Epub 2003 Aug 26.

PMID:
12944322
[PubMed - indexed for MEDLINE]
Free Article
12.

Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability.

Beugnet A, Tee AR, Taylor PM, Proud CG.

Biochem J. 2003 Jun 1;372(Pt 2):555-66. Erratum in: Biochem J. 2003 Aug 1;373(Pt 3):999.

PMID:
12611592
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Endotoxin induces differential regulation of mTOR-dependent signaling in skeletal muscle and liver of neonatal pigs.

Kimball SR, Orellana RA, O'Connor PM, Suryawan A, Bush JA, Nguyen HV, Thivierge MC, Jefferson LS, Davis TA.

Am J Physiol Endocrinol Metab. 2003 Sep;285(3):E637-44. Epub 2003 May 28.

PMID:
12773308
[PubMed - indexed for MEDLINE]
Free Article
14.

Developmental decline in components of signal transduction pathways regulating protein synthesis in pig muscle.

Kimball SR, Farrell PA, Nguyen HV, Jefferson LS, Davis TA.

Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E585-92.

PMID:
11832361
[PubMed - indexed for MEDLINE]
Free Article
15.

Developmental changes in the feeding-induced stimulation of translation initiation in muscle of neonatal pigs.

Davis TA, Nguyen HV, Suryawan A, Bush JA, Jefferson LS, Kimball SR.

Am J Physiol Endocrinol Metab. 2000 Dec;279(6):E1226-34.

PMID:
11093908
[PubMed - indexed for MEDLINE]
Free Article
16.

Time course of leucine-induced 4E-BP1 and S6K1 phosphorylation in the liver and skeletal muscle of rats.

Yoshizawa F, Sekizawa H, Hirayama S, Hatakeyama A, Nagasawa T, Sugahara K.

J Nutr Sci Vitaminol (Tokyo). 2001 Aug;47(4):311-5.

PMID:
11767213
[PubMed - indexed for MEDLINE]
17.

Modulation of translation initiation in rat skeletal muscle and liver in response to food intake.

Yoshizawa F, Kimball SR, Jefferson LS.

Biochem Biophys Res Commun. 1997 Nov 26;240(3):825-31.

PMID:
9398653
[PubMed - indexed for MEDLINE]
18.

Tissue-specific regulation of 4E-BP1 and S6K1 phosphorylation by alpha-ketoisocaproate.

Yoshizawa F, Sekizawa H, Hirayama S, Yamazaki Y, Nagasawa T, Sugahara K.

J Nutr Sci Vitaminol (Tokyo). 2004 Feb;50(1):56-60.

PMID:
15228219
[PubMed - indexed for MEDLINE]
19.

Dietary arginine supplementation increases mTOR signaling activity in skeletal muscle of neonatal pigs.

Yao K, Yin YL, Chu W, Liu Z, Deng D, Li T, Huang R, Zhang J, Tan B, Wang W, Wu G.

J Nutr. 2008 May;138(5):867-72.

PMID:
18424593
[PubMed - indexed for MEDLINE]
Free Article
20.

Sepsis-induced suppression of skeletal muscle translation initiation mediated by tumor necrosis factor alpha.

Lang CH, Frost RA.

Metabolism. 2007 Jan;56(1):49-57.

PMID:
17161226
[PubMed - indexed for MEDLINE]

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