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Results: 1 to 20 of 140

1.

Disparate effects of telomere attrition on gene expression during replicative senescence of human mammary epithelial cells cultured under different conditions.

Zhang H, Herbert BS, Pan KH, Shay JW, Cohen SN.

Oncogene. 2004 Aug 19;23(37):6193-8.

PMID:
15195144
[PubMed - indexed for MEDLINE]
2.

Senescence occurs with hTERT repression and limited telomere shortening in human oral keratinocytes cultured with feeder cells.

Kang MK, Kameta A, Shin KH, Baluda MA, Park NH.

J Cell Physiol. 2004 Jun;199(3):364-70.

PMID:
15095283
[PubMed - indexed for MEDLINE]
3.

Senescence delay of human diploid fibroblast induced by anti-sense p16INK4a expression.

Duan J, Zhang Z, Tong T.

J Biol Chem. 2001 Dec 21;276(51):48325-31. Epub 2001 Oct 17.

PMID:
11606567
[PubMed - indexed for MEDLINE]
Free Article
4.

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions.

Ramirez RD, Morales CP, Herbert BS, Rohde JM, Passons C, Shay JW, Wright WE.

Genes Dev. 2001 Feb 15;15(4):398-403.

PMID:
11230148
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The human melanocyte: a model system to study the complexity of cellular aging and transformation in non-fibroblastic cells.

Bandyopadhyay D, Timchenko N, Suwa T, Hornsby PJ, Campisi J, Medrano EE.

Exp Gerontol. 2001 Aug;36(8):1265-75. Review.

PMID:
11602203
[PubMed - indexed for MEDLINE]
6.

Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci.

Zhang H, Pan KH, Cohen SN.

Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3251-6. Epub 2003 Mar 7.

PMID:
12626749
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Microarray analysis of replicative senescence.

Shelton DN, Chang E, Whittier PS, Choi D, Funk WD.

Curr Biol. 1999 Sep 9;9(17):939-45.

PMID:
10508581
[PubMed - indexed for MEDLINE]
Free Article
8.

Human fibroblast replicative senescence can occur in the absence of extensive cell division and short telomeres.

Munro J, Steeghs K, Morrison V, Ireland H, Parkinson EK.

Oncogene. 2001 Jun 14;20(27):3541-52.

PMID:
11429701
[PubMed - indexed for MEDLINE]
Free Article
9.

p16(INK4a) inactivation is not required to immortalize human mammary epithelial cells.

Herbert BS, Wright WE, Shay JW.

Oncogene. 2002 Nov 7;21(51):7897-900.

PMID:
12420227
[PubMed - indexed for MEDLINE]
Free Article
10.

Significant role for p16INK4a in p53-independent telomere-directed senescence.

Jacobs JJ, de Lange T.

Curr Biol. 2004 Dec 29;14(24):2302-8.

PMID:
15620660
[PubMed - indexed for MEDLINE]
Free Article
11.
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13.

Low oxygen delays fibroblast senescence despite shorter telomeres.

Betts DH, Perrault SD, King WA.

Biogerontology. 2008 Feb;9(1):19-31. Epub 2007 Oct 20.

PMID:
17952625
[PubMed - indexed for MEDLINE]
14.

Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16(ink4a).

Kosar M, Bartkova J, Hubackova S, Hodny Z, Lukas J, Bartek J.

Cell Cycle. 2011 Feb 1;10(3):457-68. Epub 2011 Feb 1.

PMID:
21248468
[PubMed - indexed for MEDLINE]
Free Article
15.

Direct evidence from siRNA-directed "knock down" that p16(INK4a) is required for human fibroblast senescence and for limiting ras-induced epithelial cell proliferation.

Bond J, Jones C, Haughton M, DeMicco C, Kipling D, Wynford-Thomas D.

Exp Cell Res. 2004 Jan 1;292(1):151-6.

PMID:
14720514
[PubMed - indexed for MEDLINE]
16.

Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes.

Romanov SR, Kozakiewicz BK, Holst CR, Stampfer MR, Haupt LM, Tlsty TD.

Nature. 2001 Feb 1;409(6820):633-7.

PMID:
11214324
[PubMed - indexed for MEDLINE]
17.

Contribution of p16(INK4a) to replicative senescence of human fibroblasts.

Brookes S, Rowe J, Gutierrez Del Arroyo A, Bond J, Peters G.

Exp Cell Res. 2004 Aug 15;298(2):549-59.

PMID:
15265701
[PubMed - indexed for MEDLINE]
18.

From cells to organisms: can we learn about aging from cells in culture?

Campisi J.

Exp Gerontol. 2001 Apr;36(4-6):607-18. Review.

PMID:
11295503
[PubMed - indexed for MEDLINE]
19.

Telomere length and the expression of natural telomeric genes in human fibroblasts.

Ning Y, Xu JF, Li Y, Chavez L, Riethman HC, Lansdorp PM, Weng NP.

Hum Mol Genet. 2003 Jun 1;12(11):1329-36.

PMID:
12761048
[PubMed - indexed for MEDLINE]
Free Article
20.

Inactivation of p53 function in cultured human mammary epithelial cells turns the telomere-length dependent senescence barrier from agonescence into crisis.

Garbe JC, Holst CR, Bassett E, Tlsty T, Stampfer MR.

Cell Cycle. 2007 Aug 1;6(15):1927-36. Epub 2007 May 30.

PMID:
17671422
[PubMed - indexed for MEDLINE]
Free Article

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