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Items: 1 to 20 of 162


Structural basis for vinculin activation at sites of cell adhesion.

Bakolitsa C, Cohen DM, Bankston LA, Bobkov AA, Cadwell GW, Jennings L, Critchley DR, Craig SW, Liddington RC.

Nature. 2004 Jul 29;430(6999):583-6. Epub 2004 Jun 13.


The structure and regulation of vinculin.

Ziegler WH, Liddington RC, Critchley DR.

Trends Cell Biol. 2006 Sep;16(9):453-60. Epub 2006 Aug 8. Review.


Crystal structure of human vinculin.

Borgon RA, Vonrhein C, Bricogne G, Bois PR, Izard T.

Structure. 2004 Jul;12(7):1189-97. Epub 2004 Jun 3.


Three-dimensional structure of vinculin bound to actin filaments.

Janssen ME, Kim E, Liu H, Fujimoto LM, Bobkov A, Volkmann N, Hanein D.

Mol Cell. 2006 Jan 20;21(2):271-81.


Insights into allosteric control of vinculin function from its large scale conformational dynamics.

Chen Y, Dokholyan NV.

J Biol Chem. 2006 Sep 29;281(39):29148-54. Epub 2006 Aug 6.


Vinculin activation by talin through helical bundle conversion.

Izard T, Evans G, Borgon RA, Rush CL, Bricogne G, Bois PR.

Nature. 2004 Jan 8;427(6970):171-5. Epub 2003 Dec 31.


Vinculin binding in its closed conformation by a helix addition mechanism.

Nhieu GT, Izard T.

EMBO J. 2007 Oct 31;26(21):4588-96. Epub 2007 Oct 11. Erratum in: EMBO J. 2008 Mar 19;27(6):922.


Coincidence of actin filaments and talin is required to activate vinculin.

Chen H, Choudhury DM, Craig SW.

J Biol Chem. 2006 Dec 29;281(52):40389-98. Epub 2006 Oct 29.


The vinculin binding sites of talin and alpha-actinin are sufficient to activate vinculin.

Bois PR, O'Hara BP, Nietlispach D, Kirkpatrick J, Izard T.

J Biol Chem. 2006 Mar 17;281(11):7228-36. Epub 2006 Jan 9.


Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin.

Cohen DM, Chen H, Johnson RP, Choudhury B, Craig SW.

J Biol Chem. 2005 Apr 29;280(17):17109-17. Epub 2005 Feb 22.


Structural basis for amplifying vinculin activation by talin.

Izard T, Vonrhein C.

J Biol Chem. 2004 Jun 25;279(26):27667-78. Epub 2004 Apr 7.


Cell biology: how to build a cell junction.

Weis WI.

Nature. 2004 Jul 29;430(6999):513-5. No abstract available.


Characterization of an F-actin-binding domain in the cytoskeletal protein vinculin.

Menkel AR, Kroemker M, Bubeck P, Ronsiek M, Nikolai G, Jockusch BM.

J Cell Biol. 1994 Sep;126(5):1231-40.


Comparative biochemical analysis suggests that vinculin and metavinculin cooperate in muscular adhesion sites.

Witt S, Zieseniss A, Fock U, Jockusch BM, Illenberger S.

J Biol Chem. 2004 Jul 23;279(30):31533-43. Epub 2004 May 24.


Ligand recruitment by vinculin domains in transfected cells.

Bubeck P, Pistor S, Wehland J, Jockusch BM.

J Cell Sci. 1997 Jun;110 ( Pt 12):1361-71.


Integrin connections to the cytoskeleton through talin and vinculin.

Ziegler WH, Gingras AR, Critchley DR, Emsley J.

Biochem Soc Trans. 2008 Apr;36(Pt 2):235-9. doi: 10.1042/BST0360235. Review.


An autoinhibited structure of α-catenin and its implications for vinculin recruitment to adherens junctions.

Ishiyama N, Tanaka N, Abe K, Yang YJ, Abbas YM, Umitsu M, Nagar B, Bueler SA, Rubinstein JL, Takeichi M, Ikura M.

J Biol Chem. 2013 May 31;288(22):15913-25. doi: 10.1074/jbc.M113.453928. Epub 2013 Apr 15.


αE-catenin is an autoinhibited molecule that coactivates vinculin.

Choi HJ, Pokutta S, Cadwell GW, Bobkov AA, Bankston LA, Liddington RC, Weis WI.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8576-81. doi: 10.1073/pnas.1203906109. Epub 2012 May 14.


Crystal structure of the vinculin tail suggests a pathway for activation.

Bakolitsa C, de Pereda JM, Bagshaw CR, Critchley DR, Liddington RC.

Cell. 1999 Dec 10;99(6):603-13.

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