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15084661,35431249,11160418,19158430,27629715,15772340,25168729,22406441,25810517,18096814,17116874,15704187,31927145,32966331,31208706,15331417,23372648,22660329,24662099,30605056,30454039,10952022,29240990,29093372,23576130,23771815,15287908,16551656,29914551,29341269,26742512,26563932,31002190,28821400,20110613,25319699,11778650,10487842,21239853,15590663,21244429,9265639,23530514,16385556,25450380,11790115,11325345,28487416,23225010,15910781,28073379,32645028,27151330,16468304,26088696,30362029,26898910,17431643,30553886,32019603,24060675,27700119,11404403,26971933,35002518,27227450,25178404,23768694,34239348,24495298,28390823,27031470,11099491,29048465,15014128,18537540,20930272,21708455,22273754,32141089,17472708,18486110,24613671,18422760,29378642,35285073,15071107,32854776,30412496,21875408,27505013,29940109,31627745,24117759,16282321,22457776,30850702,19771166,31121890,22965147,32075924,29161341,21219931,32732283,31043574,18690835,21222605,32286945,22785400,19020010,32065788,20371804,30102892,30907317,33452414,31991844,33671444,32067279,23197725,23554921,17119294,28557010,34737043,19360426,29714053,33069251,18198424,31287614,32380752,32770501,21421841,22950913,25553453,19834067,32087290,29687257,17336088,32716575,24861310,18549781,31780819,8631862,19798558,19542222,20101004,23386614,32027932,32827351,19457098,19474305,34330900,20354705,31281579,36271678,35904715,31883973,29865055,21741125,23345405,35307993,24050316,26718979,32677986,25973140,33362250,30540497,25051234,12151510,19523444,33895131,28246336,31165579,35701718,23594602,17012232,29555950,32023927,30391539,23129750,17478890,31004062,9763475,15716586,31408876,36399277,24503618,26538644,31234523,30557391,32456156,22355408,30194628,16541076,36442093,34450034,32567070,36336241,33908427,21683475,33948899,35105352,30958361,25207746,29476081,30566579,22496568,11152675,31150730,32484608,12218652,18059472,32544084,30257562,20031278,31673052,22869717,32260279,34494298,9662375,21418518,29248459,36014310,17056594,31016584,36292947,36242849,36609403,34830060,19524672,24269629,20164551,19716367,18562609,34213901,30689566,34906694,30374196,29186695,17822928,32233096,31156161,31831060,32857841,31379503,32488543,32046944,24982137,29637859,31392693,7615568,19005060,33459709,10842709,29729422,31834770,17965777,16549764,36905760,25153942,32367269,23922015,34198582,22796753,30775980,18756527,36316282,12590160,36775930,20042680,29746089,32274758,31796673,36675271,22213704,22745746,22072713,34462532,33872797,25109765,22003387,30864847,33806726,20930278,23943618,23509974,31982938,23196550,20547123,15649137,31825838,30079520,20829454,31813628,23704552,20890432,33540171,33432101,19926863,36278346,35786817,19075579,36693165,33564035,22486774,32599696,24586443,20980598,19901162,19660551,32033502,36269420,19997607,31602409,16914851,31600048,25576082,36067650,23430745,23824558,34907598,19247480,14742907,30528194,33375009,21197446,18397883,15639796,21556141,17917109,15709490,33837697,23528227,12837845,32138161,10806193,25468905,17627483,33167440,19923222,31989871,36189589,37117484,21652708,31866295,18485101,33491917,34767256,33052945,23669069,23352590,35156715,32814257,21234417,31884461,32142821,30763064,10846187,33176118,29187699,23512986,16903824,20098622,8939715,30679382,36763536,30714956,32301581,31591472,36082607,23462987,21706148,23665843,32840760,33316730,34958022,36594931,35046433,35941704,33646777,36614115,30538196,23852578,33256578,25846299,30649520,22490665,15605991,21692120,17493043,19211891,30565253,21500269,36281062,20964623,19074441,36925083,25807081,34333107,31905804,27266855,36747008,23720634,30706715,8702810,22288403,32792144,18652590,21506544,34418507,36536382,19936102,9141062,31328526,23704556,20479943,20682338,35158417,20939098,31829176,32492332,30738412,22685625,14724276,33666411,32916822,32804095,28580182,8955133,36993768,29625607,20387301,32543725,35421203,22737128,24413756,29067301,25206748,14618158,18334715,33046246,24625058,24146290,30825227,23849219,31137462,35695727,30123109,37126689,21070634,28352227,22201966,25628768,34985875,22631613,21318142,32098382,36908879,36839831,23275378,27814578,33668379,21854604,36363654,26557086,36090253,24396386,27014089,22712003,33920464,15912886,26078011,34970117,22272133,34573265,30136122,32937123,26441640,36867706,36634385,21331330,26074758,30094330,21852974,21151659,28348305,25852450,32147353,32184240,32350456,21080545[uid]

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Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease.

Kawarabayashi T, Shoji M, Younkin LH, Wen-Lang L, Dickson DW, Murakami T, Matsubara E, Abe K, Ashe KH, Younkin SG. Kawarabayashi T, et al. J Neurosci. 2004 Apr 14;24(15):3801-9. doi: 10.1523/JNEUROSCI.5543-03.2004. J Neurosci. 2004. PMID: 15084661 Free PMC article.

Lipid Rafts Act as a Common Platform for Amyloid-β Oligomer-Induced Alzheimer's Disease Pathology.

Kawarabayashi T, Nakamura T, Sato K, Seino Y, Ichii S, Nakahata N, Takatama M, Westaway D, George-Hyslop PS, Shoji M. Kawarabayashi T, et al. J Alzheimers Dis. 2022;87(3):1189-1203. doi: 10.3233/JAD-215662. J Alzheimers Dis. 2022. PMID: 35431249

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

Kawarabayashi T, Younkin LH, Saido TC, Shoji M, Ashe KH, Younkin SG. Kawarabayashi T, et al. J Neurosci. 2001 Jan 15;21(2):372-81. doi: 10.1523/JNEUROSCI.21-02-00372.2001. J Neurosci. 2001. PMID: 11160418 Free PMC article.

Tau phosphorylation by cdk5 and Fyn in response to amyloid peptide Abeta (25-35): involvement of lipid rafts.

Hernandez P, Lee G, Sjoberg M, Maccioni RB. Hernandez P, et al. J Alzheimers Dis. 2009;16(1):149-56. doi: 10.3233/JAD-2009-0933. J Alzheimers Dis. 2009. PMID: 19158430

Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport.

Sherman MA, LaCroix M, Amar F, Larson ME, Forster C, Aguzzi A, Bennett DA, Ramsden M, Lesné SE. Sherman MA, et al. J Neurosci. 2016 Sep 14;36(37):9647-58. doi: 10.1523/JNEUROSCI.1899-16.2016. J Neurosci. 2016. PMID: 27629715 Free PMC article.

Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

Fryer JD, Simmons K, Parsadanian M, Bales KR, Paul SM, Sullivan PM, Holtzman DM. Fryer JD, et al. J Neurosci. 2005 Mar 16;25(11):2803-10. doi: 10.1523/JNEUROSCI.5170-04.2005. J Neurosci. 2005. PMID: 15772340 Free PMC article.

Aβ promotes VDAC1 channel dephosphorylation in neuronal lipid rafts. Relevance to the mechanisms of neurotoxicity in Alzheimer's disease.

Fernandez-Echevarria C, Díaz M, Ferrer I, Canerina-Amaro A, Marin R. Fernandez-Echevarria C, et al. Neuroscience. 2014 Oct 10;278:354-66. doi: 10.1016/j.neuroscience.2014.07.079. Epub 2014 Aug 26. Neuroscience. 2014. PMID: 25168729

Effects of the superoxide dismutase/catalase mimetic EUK-207 in a mouse model of Alzheimer's disease: protection against and interruption of progression of amyloid and tau pathology and cognitive decline.

Clausen A, Xu X, Bi X, Baudry M. Clausen A, et al. J Alzheimers Dis. 2012;30(1):183-208. doi: 10.3233/JAD-2012-111298. J Alzheimers Dis. 2012. PMID: 22406441

Tau immunotherapy modulates both pathological tau and upstream amyloid pathology in an Alzheimer's disease mouse model.

Castillo-Carranza DL, Guerrero-Muñoz MJ, Sengupta U, Hernandez C, Barrett AD, Dineley K, Kayed R. Castillo-Carranza DL, et al. J Neurosci. 2015 Mar 25;35(12):4857-68. doi: 10.1523/JNEUROSCI.4989-14.2015. J Neurosci. 2015. PMID: 25810517 Free PMC article.

Membrane-bound beta-amyloid oligomers are recruited into lipid rafts by a fyn-dependent mechanism.

Williamson R, Usardi A, Hanger DP, Anderton BH. Williamson R, et al. FASEB J. 2008 May;22(5):1552-9. doi: 10.1096/fj.07-9766com. Epub 2007 Dec 20. FASEB J. 2008. PMID: 18096814

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