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Results: 1 to 20 of 132

1.

IRAK4 kinase activity is redundant for interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness.

Qin J, Jiang Z, Qian Y, Casanova JL, Li X.

J Biol Chem. 2004 Jun 18;279(25):26748-53. Epub 2004 Apr 14.

PMID:
15084582
[PubMed - indexed for MEDLINE]
Free Article
2.

The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling.

Lye E, Mirtsos C, Suzuki N, Suzuki S, Yeh WC.

J Biol Chem. 2004 Sep 24;279(39):40653-8. Epub 2004 Jul 29.

PMID:
15292196
[PubMed - indexed for MEDLINE]
Free Article
3.

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase.

Li S, Strelow A, Fontana EJ, Wesche H.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5567-72.

PMID:
11960013
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

TLR8-mediated NF-kappaB and JNK activation are TAK1-independent and MEKK3-dependent.

Qin J, Yao J, Cui G, Xiao H, Kim TW, Fraczek J, Wightman P, Sato S, Akira S, Puel A, Casanova JL, Su B, Li X.

J Biol Chem. 2006 Jul 28;281(30):21013-21. Epub 2006 May 31.

PMID:
16737960
[PubMed - indexed for MEDLINE]
Free Article
5.

Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol.

Jiang Z, Ninomiya-Tsuji J, Qian Y, Matsumoto K, Li X.

Mol Cell Biol. 2002 Oct;22(20):7158-67.

PMID:
12242293
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Effects of IL-1 receptor-associated kinase (IRAK) expression on IL-1 signaling are independent of its kinase activity.

Knop J, Martin MU.

FEBS Lett. 1999 Apr 1;448(1):81-5.

PMID:
10217414
[PubMed - indexed for MEDLINE]
Free Article
7.

Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction.

Brint EK, Fitzgerald KA, Smith P, Coyle AJ, Gutierrez-Ramos JC, Fallon PG, O'Neill LA.

J Biol Chem. 2002 Dec 20;277(51):49205-11. Epub 2002 Oct 3.

PMID:
12368275
[PubMed - indexed for MEDLINE]
Free Article
8.

Interleukin 1/Toll-like receptor-induced autophosphorylation activates interleukin 1 receptor-associated kinase 4 and controls cytokine induction in a cell type-specific manner.

Cushing L, Stochaj W, Siegel M, Czerwinski R, Dower K, Wright Q, Hirschfield M, Casanova JL, Picard C, Puel A, Lin LL, Rao VR.

J Biol Chem. 2014 Apr 11;289(15):10865-75. doi: 10.1074/jbc.M113.544809. Epub 2014 Feb 24.

PMID:
24567333
[PubMed - indexed for MEDLINE]
9.

IRAK-4 kinase activity is required for interleukin-1 (IL-1) receptor- and toll-like receptor 7-mediated signaling and gene expression.

Koziczak-Holbro M, Joyce C, Glück A, Kinzel B, Müller M, Tschopp C, Mathison JC, Davis CN, Gram H.

J Biol Chem. 2007 May 4;282(18):13552-60. Epub 2007 Mar 2.

PMID:
17337443
[PubMed - indexed for MEDLINE]
Free Article
10.
11.

NF-kappaB- and C/EBPbeta-driven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages.

Basak C, Pathak SK, Bhattacharyya A, Mandal D, Pathak S, Kundu M.

J Biol Chem. 2005 Feb 11;280(6):4279-88. Epub 2004 Nov 23.

PMID:
15561713
[PubMed - indexed for MEDLINE]
Free Article
12.

Identification of essential regions in the cytoplasmic tail of interleukin-1 receptor accessory protein critical for interleukin-1 signaling.

Radons J, Gabler S, Wesche H, Korherr C, Hofmeister R, Falk W.

J Biol Chem. 2002 May 10;277(19):16456-63. Epub 2002 Mar 5.

PMID:
11880380
[PubMed - indexed for MEDLINE]
Free Article
13.
14.

The kinase activity of IL-1 receptor-associated kinase 4 is required for interleukin-1 receptor/toll-like receptor-induced TAK1-dependent NFkappaB activation.

Fraczek J, Kim TW, Xiao H, Yao J, Wen Q, Li Y, Casanova JL, Pryjma J, Li X.

J Biol Chem. 2008 Nov 14;283(46):31697-705. doi: 10.1074/jbc.M804779200. Epub 2008 Sep 15.

PMID:
18794297
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

IRAK and TAK1 are required for IL-18-mediated signaling.

Wald D, Commane M, Stark GR, Li X.

Eur J Immunol. 2001 Dec;31(12):3747-54.

PMID:
11745395
[PubMed - indexed for MEDLINE]
16.

Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production.

Kanakaraj P, Schafer PH, Cavender DE, Wu Y, Ngo K, Grealish PF, Wadsworth SA, Peterson PA, Siekierka JJ, Harris CA, Fung-Leung WP.

J Exp Med. 1998 Jun 15;187(12):2073-9.

PMID:
9625767
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling.

Kollewe C, Mackensen AC, Neumann D, Knop J, Cao P, Li S, Wesche H, Martin MU.

J Biol Chem. 2004 Feb 13;279(7):5227-36. Epub 2003 Nov 18.

PMID:
14625308
[PubMed - indexed for MEDLINE]
Free Article
18.

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor.

Burns K, Clatworthy J, Martin L, Martinon F, Plumpton C, Maschera B, Lewis A, Ray K, Tschopp J, Volpe F.

Nat Cell Biol. 2000 Jun;2(6):346-51.

PMID:
10854325
[PubMed - indexed for MEDLINE]

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