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Results: 1 to 20 of 607

1.

In vivo vulnerability to competition by endogenous dopamine: comparison of the D2 receptor agonist radiotracer (-)-N-[11C]propyl-norapomorphine ([11C]NPA) with the D2 receptor antagonist radiotracer [11C]-raclopride.

Narendran R, Hwang DR, Slifstein M, Talbot PS, Erritzoe D, Huang Y, Cooper TB, Martinez D, Kegeles LS, Abi-Dargham A, Laruelle M.

Synapse. 2004 Jun 1;52(3):188-208.

PMID:
15065219
[PubMed - indexed for MEDLINE]
2.

Measurement of the proportion of D2 receptors configured in state of high affinity for agonists in vivo: a positron emission tomography study using [11C]N-propyl-norapomorphine and [11C]raclopride in baboons.

Narendran R, Hwang DR, Slifstein M, Hwang Y, Huang Y, Ekelund J, Guillin O, Scher E, Martinez D, Laruelle M.

J Pharmacol Exp Ther. 2005 Oct;315(1):80-90. Epub 2005 Jul 12.

PMID:
16014571
[PubMed - indexed for MEDLINE]
Free Article
3.

Binding characteristics and sensitivity to endogenous dopamine of [11C]-(+)-PHNO, a new agonist radiotracer for imaging the high-affinity state of D2 receptors in vivo using positron emission tomography.

Ginovart N, Galineau L, Willeit M, Mizrahi R, Bloomfield PM, Seeman P, Houle S, Kapur S, Wilson AA.

J Neurochem. 2006 May;97(4):1089-103. Epub 2006 Apr 5.

PMID:
16606355
[PubMed - indexed for MEDLINE]
4.

A comparative evaluation of the dopamine D(2/3) agonist radiotracer [11C](-)-N-propyl-norapomorphine and antagonist [11C]raclopride to measure amphetamine-induced dopamine release in the human striatum.

Narendran R, Mason NS, Laymon CM, Lopresti BJ, Velasquez ND, May MA, Kendro S, Martinez D, Mathis CA, Frankle WG.

J Pharmacol Exp Ther. 2010 May;333(2):533-9. doi: 10.1124/jpet.109.163501. Epub 2010 Jan 26.

PMID:
20103586
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Dopamine (D2/3) receptor agonist positron emission tomography radiotracer [11C]-(+)-PHNO is a D3 receptor preferring agonist in vivo.

Narendran R, Slifstein M, Guillin O, Hwang Y, Hwang DR, Scher E, Reeder S, Rabiner E, Laruelle M.

Synapse. 2006 Dec 1;60(7):485-95.

PMID:
16952157
[PubMed - indexed for MEDLINE]
6.

Positron-labeled dopamine agonists for probing the high affinity states of dopamine subtype 2 receptors.

Hwang DR, Narendran R, Laruelle M.

Bioconjug Chem. 2005 Jan-Feb;16(1):27-31.

PMID:
15656572
[PubMed - indexed for MEDLINE]
7.

PET studies of binding competition between endogenous dopamine and the D1 radiotracer [11C]NNC 756.

Abi-Dargham A, Simpson N, Kegeles L, Parsey R, Hwang DR, Anjilvel S, Zea-Ponce Y, Lombardo I, Van Heertum R, Mann JJ, Foged C, Halldin C, Laruelle M.

Synapse. 1999 May;32(2):93-109.

PMID:
10231129
[PubMed - indexed for MEDLINE]
8.

Amphetamine pretreatment induces a change in both D2-Receptor density and apparent affinity: a [11C]raclopride positron emission tomography study in cats.

Ginovart N, Wilson AA, Houle S, Kapur S.

Biol Psychiatry. 2004 Jun 15;55(12):1188-94.

PMID:
15184038
[PubMed - indexed for MEDLINE]
9.

Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: a comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride.

Seneca N, Finnema SJ, Farde L, Gulyás B, Wikström HV, Halldin C, Innis RB.

Synapse. 2006 Apr;59(5):260-9.

PMID:
16416444
[PubMed - indexed for MEDLINE]
10.

In vivo characterization of the pharmacokinetics and pharmacological properties of [11C]-(+)-PHNO in rats using an intracerebral beta-sensitive system.

Galineau L, Wilson AA, Garcia A, Houle S, Kapur S, Ginovart N.

Synapse. 2006 Aug;60(2):172-83.

PMID:
16715499
[PubMed - indexed for MEDLINE]
11.

Amphetamine-induced dopamine release: duration of action as assessed with the D2/3 receptor agonist radiotracer (-)-N-[(11)C]propyl-norapomorphine ([11C]NPA) in an anesthetized nonhuman primate.

Narendran R, Slifstein M, Hwang DR, Hwang Y, Scher E, Reeder S, Martinez D, Laruelle M.

Synapse. 2007 Feb;61(2):106-9. No abstract available.

PMID:
17117423
[PubMed - indexed for MEDLINE]
12.

Quantitative analysis of (-)-N-(11)C-propyl-norapomorphine in vivo binding in nonhuman primates.

Hwang DR, Narendran R, Huang Y, Slifstein M, Talbot PS, Sudo Y, Van Berckel BN, Kegeles LS, Martinez D, Laruelle M.

J Nucl Med. 2004 Feb;45(2):338-46.

PMID:
14960658
[PubMed - indexed for MEDLINE]
Free Article
13.

Dopamine D2 receptor radiotracers [(11)C](+)-PHNO and [(3)H]raclopride are indistinguishably inhibited by D2 agonists and antagonists ex vivo.

McCormick PN, Kapur S, Seeman P, Wilson AA.

Nucl Med Biol. 2008 Jan;35(1):11-7. Epub 2007 Nov 19.

PMID:
18158938
[PubMed - indexed for MEDLINE]
14.

Modulation of striatal dopamine release by 5-HT2A and 5-HT2C receptor antagonists: [11C]raclopride PET studies in the rat.

Egerton A, Ahmad R, Hirani E, Grasby PM.

Psychopharmacology (Berl). 2008 Nov;200(4):487-96. doi: 10.1007/s00213-008-1226-4. Epub 2008 Jul 3.

PMID:
18597077
[PubMed - indexed for MEDLINE]
15.

Dopamine D2High receptors measured ex vivo are elevated in amphetamine-sensitized animals.

Seeman P.

Synapse. 2009 Mar;63(3):186-92. doi: 10.1002/syn.20595.

PMID:
19086090
[PubMed - indexed for MEDLINE]
16.

Ex vivo [11C]-(+)-PHNO binding is unchanged in animal models displaying increased high-affinity states of the D2 receptor in vitro.

McCormick PN, Kapur S, Reckless G, Wilson AA.

Synapse. 2009 Nov;63(11):998-1009. doi: 10.1002/syn.20671.

PMID:
19598174
[PubMed - indexed for MEDLINE]
17.

(-)-N-[(11)C]propyl-norapomorphine: a positron-labeled dopamine agonist for PET imaging of D(2) receptors.

Hwang DR, Kegeles LS, Laruelle M.

Nucl Med Biol. 2000 Aug;27(6):533-9.

PMID:
11056366
[PubMed - indexed for MEDLINE]
18.

Modulation of amphetamine-induced dopamine release by group II metabotropic glutamate receptor agonist LY354740 in non-human primates studied with positron emission tomography.

van Berckel BN, Kegeles LS, Waterhouse R, Guo N, Hwang DR, Huang Y, Narendran R, Van Heertum R, Laruelle M.

Neuropsychopharmacology. 2006 May;31(5):967-77.

PMID:
16177807
[PubMed - indexed for MEDLINE]
Free Article
19.

Positron emission tomography imaging of amphetamine-induced dopamine release in the human cortex: a comparative evaluation of the high affinity dopamine D2/3 radiotracers [11C]FLB 457 and [11C]fallypride.

Narendran R, Frankle WG, Mason NS, Rabiner EA, Gunn RN, Searle GE, Vora S, Litschge M, Kendro S, Cooper TB, Mathis CA, Laruelle M.

Synapse. 2009 Jun;63(6):447-61. doi: 10.1002/syn.20628.

PMID:
19217025
[PubMed - indexed for MEDLINE]
20.

The competition between endogenous dopamine and radioligands for specific binding to dopamine receptors.

Cumming P, Wong DF, Dannals RF, Gillings N, Hilton J, Scheffel U, Gjedde A.

Ann N Y Acad Sci. 2002 Jun;965:440-50.

PMID:
12105119
[PubMed - indexed for MEDLINE]

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