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Items: 1 to 20 of 113

1.

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways.

Björkbacka H, Kunjathoor VV, Moore KJ, Koehn S, Ordija CM, Lee MA, Means T, Halmen K, Luster AD, Golenbock DT, Freeman MW.

Nat Med. 2004 Apr;10(4):416-21. Epub 2004 Mar 14.

PMID:
15034566
2.

Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E.

Michelsen KS, Wong MH, Shah PK, Zhang W, Yano J, Doherty TM, Akira S, Rajavashisth TB, Arditi M.

Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10679-84. Epub 2004 Jul 12.

3.

Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent.

Doz E, Noulin N, Boichot E, Guénon I, Fick L, Le Bert M, Lagente V, Ryffel B, Schnyder B, Quesniaux VF, Couillin I.

J Immunol. 2008 Jan 15;180(2):1169-78.

4.
5.

Atherosclerosis and innate immune signaling.

Laberge MA, Moore KJ, Freeman MW.

Ann Med. 2005;37(2):130-40. Review.

PMID:
16026120
6.

Toll-like receptor-dependent activation of antigen-presenting cells affects adaptive immunity to Helicobacter pylori.

Rad R, Brenner L, Krug A, Voland P, Mages J, Lang R, Schwendy S, Reindl W, Dossumbekova A, Ballhorn W, Wagner H, Schmid RM, Bauer S, Prinz C.

Gastroenterology. 2007 Jul;133(1):150-163.e3. Epub 2007 May 3.

PMID:
17631139
7.

The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung.

Wieland CW, Florquin S, Maris NA, Hoebe K, Beutler B, Takeda K, Akira S, van der Poll T.

J Immunol. 2005 Nov 1;175(9):6042-9.

9.

IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium tuberculosis infection.

Fremond CM, Togbe D, Doz E, Rose S, Vasseur V, Maillet I, Jacobs M, Ryffel B, Quesniaux VF.

J Immunol. 2007 Jul 15;179(2):1178-89.

10.

The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.

Björkbacka H, Fitzgerald KA, Huet F, Li X, Gregory JA, Lee MA, Ordija CM, Dowley NE, Golenbock DT, Freeman MW.

Physiol Genomics. 2004 Nov 17;19(3):319-30. Epub 2004 Sep 14.

11.

[Frontier of mycobacterium research--host vs. mycobacterium].

Okada M, Shirakawa T.

Kekkaku. 2005 Sep;80(9):613-29. Japanese.

PMID:
16245793
12.

Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.

Hise AG, Daehnel K, Gillette-Ferguson I, Cho E, McGarry HF, Taylor MJ, Golenbock DT, Fitzgerald KA, Kazura JW, Pearlman E.

J Immunol. 2007 Jan 15;178(2):1068-76.

13.
14.

Deficiencies of myeloid differentiation factor 88, Toll-like receptor 2 (TLR2), or TLR4 produce specific defects in macrophage cytokine secretion induced by Helicobacter pylori.

Obonyo M, Sabet M, Cole SP, Ebmeyer J, Uematsu S, Akira S, Guiney DG.

Infect Immun. 2007 May;75(5):2408-14. Epub 2007 Mar 12.

15.

Functional role for toll-like receptors in atherosclerosis and arterial remodeling.

Vink A, de Kleijn DP, Pasterkamp G.

Curr Opin Lipidol. 2004 Oct;15(5):515-21. Review. Erratum in: Curr Opin Lipidol. 2004 Dec;15(6):715.

PMID:
15361786
16.

The scaffold MyD88 acts to couple protein kinase Cepsilon to Toll-like receptors.

Faisal A, Saurin A, Gregory B, Foxwell B, Parker PJ.

J Biol Chem. 2008 Jul 4;283(27):18591-600. doi: 10.1074/jbc.M710330200. Epub 2008 May 5.

17.

Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation.

Johnson AC, Heinzel FP, Diaconu E, Sun Y, Hise AG, Golenbock D, Lass JH, Pearlman E.

Invest Ophthalmol Vis Sci. 2005 Feb;46(2):589-95.

PMID:
15671286
18.

CCR4 is a key modulator of innate immune responses.

Ness TL, Ewing JL, Hogaboam CM, Kunkel SL.

J Immunol. 2006 Dec 1;177(11):7531-9.

19.

MyDths and un-TOLLed truths: sensor, instructive and effector immunity to tuberculosis.

Reiling N, Ehlers S, Hölscher C.

Immunol Lett. 2008 Feb 15;116(1):15-23. doi: 10.1016/j.imlet.2007.11.015. Epub 2007 Dec 26. Review.

PMID:
18191460
20.

Proinflammatory cytokine production in liver regeneration is Myd88-dependent, but independent of Cd14, Tlr2, and Tlr4.

Campbell JS, Riehle KJ, Brooling JT, Bauer RL, Mitchell C, Fausto N.

J Immunol. 2006 Feb 15;176(4):2522-8.

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