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15024741,16168118,11192759,15863145,12655560,16261400,12955716,16847550,17850627,17319787,17250666,12203997,14517958,11748848,16575464,11606101,15564800,12872252,10660329,15365993,10790213,10188893,20135348,17851763,17080309,10090482,10874312,17148771,16644204,18483852,18431737,17453335,16939956,12204006,11972384,16324400,16616110,12872265,19016756,11102977,21190077,11102986,16417652,17997147,12774040,11754111,15217503,18957670,18176857,12497638,15552838,17063271,16537453,12938098,15712267,15172753,18821011,16284991,12402332,12442275,15059511,14576434,12759930,12552570,19011960,18559594,12673801,10029077,21156238,12521547,15468897,18097605,20514903,10642429,17011978,21553119,16084575,9180858,9816013,12655567,15733268,14658222,11237395,11556836,19649703,18694767,16085232,18546071,12673274,12955719,12883740,22366370,10980541,11857748,12717301,20810544,20213081,8665505,12442265,20804917,11106241,19661094,25418591,12879478,12112655,12923317,11358831,12101561,20859677,12362976,20400477,22044689,12360411,9192828,18489799,11084537,20507347,21847643,14555511,9796975,10706125,9586400,11710835,14518257,10612800,14959510,14647210,16507150,12543797,10806719,21324516,12585647,11462239,11234491,12375043,32180084,11848488,19805903,12097290,19941162,24372583,21535297,16826315,10435912,20472656,11933205,14668547,12815604,9516977,11802209,12353265,11309330,12518519,17018160,19877752,11112219,9523200,24136930,11802208,22425665,12124354,11504767,11510120,10592755,11857075,23096355,15951958,12566964,12112981,12227949,14689060,17603881,8875917,11597388,15803363,16760289,12097257,17561994,12819403,16758124,15146557,12460933,11180604,11251181,8807330,11938448,24130102,11807980,12655574,16944270,14722926,15918047,22752289,12181777,23683081,12928470,21232165,20848184,24894343,12014998,10595259,14507240,27826754,12188064,12100744,12767038,23697973,12429618,23096105,9333265,15550590,23536787,11139251,35578052,23082475,22382806,10595257,10388131,24528374,22874498,10595255,20935267,15668291,12142080,9667259,11793480,10356923,22116506,24800917,20051368,21945869,12727813,15026808,14661631,15951956,25526195,28324225,12569346,10486320,26535628,11759816,9507390,11091655,21281038,11798746,19619314,8538041,11897832,25678442,25191729,16931905,26028024,26656232,12666278,22798144,18279628,21126756,11263939,11162473,17972177,18627636,11506493,19899408,12060539,22923021,26992017,18783588,9459083,14746861,17503080,12126570,21318380,26988823,11855879,32451972,11499690,25069718,27425403,19246281,20459916,20353281,30309218,21213370,26320393,26187060,14732180,11180606,17922257,15876585,26289772,20711702,18294609,12237285,28500412,14973102,21497495,12440810,12847614,24472143,26911350,23779253,22752604,14965559,20485165,11400546,8968716,12894890,7939630,15683621,23806170,16529032,32468491,16736282,8956054,10866029,11784554,14647209,15170666,18559571,18006916,23372765,21390833,20198797,26757435,16768054,23397983,14531499,15809716,9121520,11956590,28033443,9121523,9121524,9264194,15015615,12474142,25371446,19499246,15010292,23975082,12942367,8788019,21337561,11038838,12070551,25455630,9150149,20033483,22311583,21404118,16603649,11481082,20877337,10571952,24389207,18256760,15983021,28285342,15053073,15557797,9121519,22843497,10480351,25366421,8602198,14986830,15535929,19353265,16464398,11680024,8602196,10467410,21733796,10952097,15060102,9598872,26843898,30120466,10539900,11109172,9452076,19875889,16540750,18512148,23996866,17386038,10206407,22144684,27160020,32481735,11091610,19383376,16896052,15590954,23113073,9155062,25630211,20380699,30111881,20181317,9819477,15889636,22662244,22098958,27262228,14599878,22713736,18334730,12777742,21410590,19760496,11745474,31528241,23354980,14569140,22229226,16033919,23069641,17909202,24993905,12190286,18556884,12051869,9150173,19087709,23350365,21194739,12151349,26951538,20067102,23269703,22274690,12858924,31161121,20222996,28730286,21285147,22274678,25353033,11598149,8602197,16632260,10997542,23156292,12241952,25375653,11794298,11860053,9119290,12359861,24137399,14658432,14965751,14710798,31419696,26436112,20223009,22147741,22274679,16284494,17986247,28970858,10070866,15970701,22370324,14744738,20664408,12053566,8654266,19423647,17968145,14707529,22042956,9695328,9652774,20233482,22493152,23910109,29464067,19656415,9121522,9121521,20233468,24711893,19434886,25960721,18759965,32164620,29021870,9150171,21559243,21294809,20349280,17998696,30967997,21319262,10870547,9091664,35356428,33156528,22897714,23946868,11905676,35693198,28959512,22491912,36831687,23802008,22168761,9677103,11836363,11091606,33471975,26132389,35760337,20099750,30128501,30834494,12696073,37113971,22754973,2776785,10451452,29755873,20233483,21604437,61359,20223008,13200080,14025710,28302092,13568406,13542864,14004043,14020114,33762751,25485290[uid]

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BRCA1 and BRCA2 mutations in women with familial or early-onset breast/ovarian cancer in the Czech Republic.

Foretova L, Machackova E, Navratilova M, Pavlu H, Hruba M, Lukesova M, Valik D. Foretova L, et al. Hum Mutat. 2004 Apr;23(4):397-8. doi: 10.1002/humu.9226. Hum Mutat. 2004. PMID: 15024741

High proportion of recurrent germline mutations in the BRCA1 gene in breast and ovarian cancer patients from the Prague area.

Pohlreich P, Zikan M, Stribrna J, Kleibl Z, Janatova M, Kotlas J, Zidovska J, Novotny J, Petruzelka L, Szabo C, Matous B. Pohlreich P, et al. Breast Cancer Res. 2005;7(5):R728-36. doi: 10.1186/bcr1282. Epub 2005 Jul 19. Breast Cancer Res. 2005. PMID: 16168118 Free PMC article.

A high occurrence of BRCA1 and BRCA2 mutations among Czech hereditary breast and breast-ovarian cancer families.

Machácková E, Foretová L, Navrátilová M, Valík D, Claes K, Messiaen L. Machácková E, et al. Cas Lek Cesk. 2000 Oct 11;139(20):635-7. Cas Lek Cesk. 2000. PMID: 11192759

Intra-abdominal carcinomatosis after prophylactic oophorectomy in women of hereditary breast ovarian cancer syndrome kindreds associated with BRCA1 and BRCA2 mutations.

Casey MJ, Synder C, Bewtra C, Narod SA, Watson P, Lynch HT. Casey MJ, et al. Gynecol Oncol. 2005 May;97(2):457-67. doi: 10.1016/j.ygyno.2005.01.039. Gynecol Oncol. 2005. PMID: 15863145

Germline mutations in the BRCA1 and BRCA2 genes in Turkish breast/ovarian cancer patients.

Manguoglu AE, Lüleci G, Ozçelik T, Colak T, Schayek H, Akaydin M, Friedman E. Manguoglu AE, et al. Hum Mutat. 2003 Apr;21(4):444-5. doi: 10.1002/humu.9119. Hum Mutat. 2003. PMID: 12655560

Incidence of BRCA1 and BRCA2 mutations in 54 Chilean families with breast/ovarian cancer, genotype-phenotype correlations.

Gallardo M, Silva A, Rubio L, Alvarez C, Torrealba C, Salinas M, Tapia T, Faundez P, Palma L, Riccio ME, Paredes H, Rodriguez M, Cruz A, Rousseau C, King MC, Camus M, Alvarez M, Carvallo P. Gallardo M, et al. Breast Cancer Res Treat. 2006 Jan;95(1):81-7. doi: 10.1007/s10549-005-9047-1. Epub 2005 Oct 27. Breast Cancer Res Treat. 2006. PMID: 16261400

Analysis of BRCA1 and BRCA2 genes in Spanish breast/ovarian cancer patients: a high proportion of mutations unique to Spain and evidence of founder effects.

Díez O, Osorio A, Durán M, Martinez-Ferrandis JI, de la Hoya M, Salazar R, Vega A, Campos B, Rodríguez-López R, Velasco E, Chaves J, Díaz-Rubio E, Jesús Cruz J, Torres M, Esteban E, Cervantes A, Alonso C, San Román JM, González-Sarmiento R, Miner C, Carracedo A, Eugenia Armengod M, Caldés T, Benítez J, Baiget M. Díez O, et al. Hum Mutat. 2003 Oct;22(4):301-12. doi: 10.1002/humu.10260. Hum Mutat. 2003. PMID: 12955716

Novel BRCA1 and BRCA2 germline mutations and assessment of mutation spectrum and prevalence in Italian breast and/or ovarian cancer families.

Giannini G, Capalbo C, Ristori E, Ricevuto E, Sidoni T, Buffone A, Cortesi E, Marchetti P, Scambia G, Tomao S, Rinaldi C, Zani M, Ferraro S, Frati L, Screpanti I, Gulino A. Giannini G, et al. Breast Cancer Res Treat. 2006 Nov;100(1):83-91. doi: 10.1007/s10549-006-9225-9. Epub 2006 May 9. Breast Cancer Res Treat. 2006. PMID: 16847550

Screening for BRCA1 and BRCA2 mutations in Eastern Finnish breast/ovarian cancer families.

Hartikainen JM, Kataja V, Pirskanen M, Arffman A, Ristonmaa U, Vahteristo P, Ryynänen M, Heinonen S, Kosma VM, Mannermaa A. Hartikainen JM, et al. Clin Genet. 2007 Oct;72(4):311-20. doi: 10.1111/j.1399-0004.2007.00866.x. Clin Genet. 2007. PMID: 17850627

The spectrum and incidence of BRCA1 pathogenic mutations in Slovak breast/ovarian cancer families.

Konecny M, Vizvaryova M, Weismanova E, Ilencikova D, Mlkva I, Weismann P, Machackova G, Kausitz J. Konecny M, et al. Neoplasma. 2007;54(2):137-42. Neoplasma. 2007. PMID: 17319787

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