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Results: 1 to 20 of 131

1.

Synthesis, modeling, and anti-tubulin activity of a D-seco paclitaxel analogue.

Barboni L, Giarlo G, Ricciutelli M, Ballini R, Georg GI, VanderVelde DG, Himes RH, Wang M, Lakdawala A, Snyder JP.

Org Lett. 2004 Feb 19;6(4):461-4.

PMID:
14961598
[PubMed - indexed for MEDLINE]
2.

Novel d-seco paclitaxel analogues: synthesis, biological evaluation, and model testing.

Barboni L, Datta A, Dutta D, Georg GI, Vander Velde DG, Himes RH, Wang M, Snyder JP.

J Org Chem. 2001 May 18;66(10):3321-9.

PMID:
11348113
[PubMed - indexed for MEDLINE]
3.

Synthesis and cytotoxicity of 2alpha-amido docetaxel analogues.

Fang WS, Liu Y, Liu HY, Xu SF, Wang L, Fang QC.

Bioorg Med Chem Lett. 2002 Jun 3;12(11):1543-6.

PMID:
12031338
[PubMed - indexed for MEDLINE]
4.

Synthesis and biological evaluation of novel macrocyclic paclitaxel analogues.

Metaferia BB, Hoch J, Glass TE, Bane SL, Chatterjee SK, Snyder JP, Lakdawala A, Cornett B, Kingston DG.

Org Lett. 2001 Aug 9;3(16):2461-4.

PMID:
11483035
[PubMed - indexed for MEDLINE]
5.

Interaction of a fluorescent paclitaxel analogue with tubulin.

Sengupta S, Boge TC, Georg GI, Himes RH.

Biochemistry. 1995 Sep 19;34(37):11889-94.

PMID:
7547924
[PubMed - indexed for MEDLINE]
6.

The taxol pharmacophore and the T-taxol bridging principle.

Kingston DG, Bane S, Snyder JP.

Cell Cycle. 2005 Feb;4(2):279-89. Epub 2005 Mar 1. Review.

PMID:
15611640
[PubMed - indexed for MEDLINE]
Free Article
7.

Structure-activity relationships study at the 3'-N position of paclitaxel. Part 2: synthesis and biological evaluation of 3'-N-thiourea- and 3'-N-thiocarbamate-bearing paclitaxel analogues.

Xue M, Long BH, Fairchild C, Johnston K, Rose WC, Kadow JF, Vyas DM, Chen SH.

Bioorg Med Chem Lett. 2000 Jun 19;10(12):1327-31.

PMID:
10890157
[PubMed - indexed for MEDLINE]
8.

Structure-activity relationships of Taxol and Taxotere analogues.

Guénard D, Guéritte-Voegelein F, Dubois J, Potier P.

J Natl Cancer Inst Monogr. 1993;(15):79-82.

PMID:
7912533
[PubMed - indexed for MEDLINE]
9.

Synthesis and structure-activity relationships of novel 2',2'-difluoro analogues of docetaxel.

Uoto K, Ohsuki S, Takenoshita H, Ishiyama T, Iimura S, Hirota Y, Mitsui I, Terasawa H, Soga T.

Chem Pharm Bull (Tokyo). 1997 Nov;45(11):1793-804.

PMID:
9396156
[PubMed - indexed for MEDLINE]
10.

Synthesis and biological evaluation of novel 9-functional heterocyclic coupled 7-deoxy-9-dihydropaclitaxel analogue.

Cheng Q, Oritani T, Horiguchi T, Yamada T, Mong Y.

Bioorg Med Chem Lett. 2000 Mar 6;10(5):517-21.

PMID:
10743961
[PubMed - indexed for MEDLINE]
11.

Synthesis and biological evaluation of C-3'NH/C-10 and C-2/C-10 modified paclitaxel analogues.

Baloglu E, Hoch JM, Chatterjee SK, Ravindra R, Bane S, Kingston DG.

Bioorg Med Chem. 2003 Apr 3;11(7):1557-68.

PMID:
12628679
[PubMed - indexed for MEDLINE]
12.

Synthesis and biological activity of A-nor-paclitaxel analogues.

Chordia MD, Kingston DG, Hamel E, Lin CM, Long BH, Fairchild CA, Johnston KA, Rose WC.

Bioorg Med Chem. 1997 May;5(5):941-7.

PMID:
9208103
[PubMed - indexed for MEDLINE]
13.

Dissecting paclitaxel-microtubule association: quantitative assessment of the 2'-OH group.

Sharma S, Lagisetti C, Poliks B, Coates RM, Kingston DG, Bane S.

Biochemistry. 2013 Apr 2;52(13):2328-36. doi: 10.1021/bi400014t. Epub 2013 Mar 19.

PMID:
23473345
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The solid state, solution and tubulin-bound conformations of agents that promote microtubule stabilization.

Jiménez-Barbero J, Amat-Guerri F, Snyder JP.

Curr Med Chem Anticancer Agents. 2002 Jan;2(1):91-122. Review.

PMID:
12678753
[PubMed - indexed for MEDLINE]
15.

Synthesis of metabolically blocked paclitaxel analogues.

Wittman MD, Altstadt TJ, Fairchild C, Hansel S, Johnston K, Kadow JF, Long BH, Rose WC, Vyas DM, Wu MJ, Zoeckler ME.

Bioorg Med Chem Lett. 2001 Mar 26;11(6):809-10.

PMID:
11277525
[PubMed - indexed for MEDLINE]
16.

Synthesis and structure-activity relationships of nonaromatic taxoids: effects of alkyl and alkenyl ester groups on cytotoxicity.

Ojima I, Kuduk SD, Pera P, Veith JM, Bernacki RJ.

J Med Chem. 1997 Jan 31;40(3):279-85.

PMID:
9022794
[PubMed - indexed for MEDLINE]
17.

Synthesis of a paclitaxel isomer: C-2-acetoxy-C-4-benzoate paclitaxel.

Chen SH, Farina V, Vyas DM, Doyle TW.

Bioorg Med Chem Lett. 1998 Aug 18;8(16):2227-30.

PMID:
9873518
[PubMed - indexed for MEDLINE]
18.

Design and synthesis of simplified taxol analogs based on the T-Taxol bioactive conformation.

Zhao J, Bane S, Snyder JP, Hu H, Mukherjee K, Slebodnick C, Kingston DG.

Bioorg Med Chem. 2011 Dec 15;19(24):7664-78. doi: 10.1016/j.bmc.2011.10.010. Epub 2011 Oct 13.

PMID:
22071526
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Synthesis and structure-activity relationships of new antitumor taxoids. Effects of cyclohexyl substitution at the C-3' and/or C-2 of taxotere (docetaxel).

Ojima I, Duclos O, Zucco M, Bissery MC, Combeau C, Vrignaud P, Riou JF, Lavelle F.

J Med Chem. 1994 Aug 5;37(16):2602-8.

PMID:
7914541
[PubMed - indexed for MEDLINE]
20.

Enhanced microtubule binding and tubulin assembly properties of conformationally constrained paclitaxel derivatives.

Shanker N, Kingston DG, Ganesh T, Yang C, Alcaraz AA, Geballe MT, Banerjee A, McGee D, Snyder JP, Bane S.

Biochemistry. 2007 Oct 16;46(41):11514-27. Epub 2007 Sep 25.

PMID:
17892304
[PubMed - indexed for MEDLINE]

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