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Items: 1 to 20 of 93

1.

Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes.

Robertson RP, Harmon J, Tran PO, Poitout V.

Diabetes. 2004 Feb;53 Suppl 1:S119-24. Review.

2.

Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection.

Robertson RP, Harmon J, Tran PO, Tanaka Y, Takahashi H.

Diabetes. 2003 Mar;52(3):581-7. Review.

3.

Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity.

Poitout V, Robertson RP.

Endocrinology. 2002 Feb;143(2):339-42. Review.

PMID:
11796484
4.

Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity.

Kaneto H, Kajimoto Y, Miyagawa J, Matsuoka T, Fujitani Y, Umayahara Y, Hanafusa T, Matsuzawa Y, Yamasaki Y, Hori M.

Diabetes. 1999 Dec;48(12):2398-406.

PMID:
10580429
5.

Role of oxidative stress in pancreatic beta-cell dysfunction.

Kajimoto Y, Kaneto H.

Ann N Y Acad Sci. 2004 Apr;1011:168-76.

PMID:
15126294
6.

[Anatomical and functional plasticity of pancreatic beta-cells and type 2 diabetes].

Cerasi E, Ktorza A.

Med Sci (Paris). 2007 Oct;23(10):885-94. Review. French.

7.

Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes.

Donath MY, Gross DJ, Cerasi E, Kaiser N.

Diabetes. 1999 Apr;48(4):738-44.

PMID:
10102689
8.

Chronic oxidative stress as a mechanism for glucose toxicity of the beta cell in type 2 diabetes.

Robertson R, Zhou H, Zhang T, Harmon JS.

Cell Biochem Biophys. 2007;48(2-3):139-46.

PMID:
17709883
9.

Identification of ATP synthase as a lipid peroxide protein adduct in pancreatic islets from humans with and without type 2 diabetes mellitus.

MacDonald MJ, Langberg EC, Tibell A, Sabat G, Kendrick MA, Szweda LI, Ostenson CG.

J Clin Endocrinol Metab. 2013 Apr;98(4):E727-31. doi: 10.1210/jc.2012-4203. Epub 2013 Mar 5.

10.

Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.

Ihara Y, Toyokuni S, Uchida K, Odaka H, Tanaka T, Ikeda H, Hiai H, Seino Y, Yamada Y.

Diabetes. 1999 Apr;48(4):927-32.

PMID:
10102716
11.

Diabetes, glucose toxicity, and oxidative stress: A case of double jeopardy for the pancreatic islet beta cell.

Robertson RP, Harmon JS.

Free Radic Biol Med. 2006 Jul 15;41(2):177-84. Epub 2006 May 4. Review.

PMID:
16814095
12.

Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants.

Tanaka Y, Gleason CE, Tran PO, Harmon JS, Robertson RP.

Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10857-62.

13.

Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?

Evans JL, Goldfine ID, Maddux BA, Grodsky GM.

Diabetes. 2003 Jan;52(1):1-8. Review.

14.

Asparagus officinalis extract controls blood glucose by improving insulin secretion and β-cell function in streptozotocin-induced type 2 diabetic rats.

Hafizur RM, Kabir N, Chishti S.

Br J Nutr. 2012 Nov 14;108(9):1586-95. doi: 10.1017/S0007114511007148. Epub 2012 Jan 6.

PMID:
22221560
15.

Protection of pancreatic beta-cells: is it feasible?

Bonora E.

Nutr Metab Cardiovasc Dis. 2008 Jan;18(1):74-83. Review.

PMID:
18096375
16.

Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat.

Tokuyama Y, Sturis J, DePaoli AM, Takeda J, Stoffel M, Tang J, Sun X, Polonsky KS, Bell GI.

Diabetes. 1995 Dec;44(12):1447-57.

PMID:
7589853
17.

Prevention of oxidative stress by adenoviral overexpression of glutathione-related enzymes in pancreatic islets.

Robertson RP, Tanaka Y, Takahashi H, Tran PO, Harmon JS.

Ann N Y Acad Sci. 2005 Jun;1043:513-20.

PMID:
16037273
18.

Involvement of oxidative stress in the pathogenesis of diabetes.

Kaneto H, Katakami N, Kawamori D, Miyatsuka T, Sakamoto K, Matsuoka TA, Matsuhisa M, Yamasaki Y.

Antioxid Redox Signal. 2007 Mar;9(3):355-66. Review.

PMID:
17184181
19.

Glucose regulation of islet stress responses and beta-cell failure in type 2 diabetes.

Jonas JC, Bensellam M, Duprez J, Elouil H, Guiot Y, Pascal SM.

Diabetes Obes Metab. 2009 Nov;11 Suppl 4:65-81. doi: 10.1111/j.1463-1326.2009.01112.x. Review.

PMID:
19817790
20.

Insulin secretion defects of human type 2 diabetic islets are corrected in vitro by a new reactive oxygen species scavenger.

Lupi R, Del Guerra S, Mancarella R, Novelli M, Valgimigli L, Pedulli GF, Paolini M, Soleti A, Filipponi F, Mosca F, Boggi U, Del Prato S, Masiello P, Marchetti P.

Diabetes Metab. 2007 Nov;33(5):340-5. Epub 2007 Jul 9.

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