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Results: 1 to 20 of 234

1.

Coenzyme Q10 can prolong C. elegans lifespan by lowering oxidative stress.

Ishii N, Senoo-Matsuda N, Miyake K, Yasuda K, Ishii T, Hartman PS, Furukawa S.

Mech Ageing Dev. 2004 Jan;125(1):41-6.

PMID:
14706236
[PubMed - indexed for MEDLINE]
2.

A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans.

Senoo-Matsuda N, Yasuda K, Tsuda M, Ohkubo T, Yoshimura S, Nakazawa H, Hartman PS, Ishii N.

J Biol Chem. 2001 Nov 9;276(45):41553-8. Epub 2001 Aug 29.

PMID:
11527963
[PubMed - indexed for MEDLINE]
Free Article
3.

The role of ubiquinone in Caenorhabditis elegans longevity.

Rodríguez-Aguilera JC, Gavilán A, Asencio C, Navas P.

Ageing Res Rev. 2005 Jan;4(1):41-53. Epub 2004 Nov 28. Review.

PMID:
15619469
[PubMed - indexed for MEDLINE]
4.

The ubiquinone-binding site of the Saccharomyces cerevisiae succinate-ubiquinone oxidoreductase is a source of superoxide.

Guo J, Lemire BD.

J Biol Chem. 2003 Nov 28;278(48):47629-35. Epub 2003 Sep 16.

PMID:
13129931
[PubMed - indexed for MEDLINE]
Free Article
5.

Oxidative stress and aging in Caenorhabditis elegans.

Ishii N.

Free Radic Res. 2000 Dec;33(6):857-64.

PMID:
11237107
[PubMed - indexed for MEDLINE]
6.

A complex II defect affects mitochondrial structure, leading to ced-3- and ced-4-dependent apoptosis and aging.

Senoo-Matsuda N, Hartman PS, Akatsuka A, Yoshimura S, Ishii N.

J Biol Chem. 2003 Jun 13;278(24):22031-6. Epub 2003 Apr 2.

PMID:
12672828
[PubMed - indexed for MEDLINE]
Free Article
7.

Adaptive responses to oxidative damage in three mutants of Caenorhabditis elegans (age-1, mev-1 and daf-16) that affect life span.

Yanase S, Yasuda K, Ishii N.

Mech Ageing Dev. 2002 Nov;123(12):1579-87.

PMID:
12470895
[PubMed - indexed for MEDLINE]
8.

Ubiquinol and a coenzyme Q reducing system protect platelet mitochondrial function of transfusional buffy coats from oxidative stress.

Merlo Pich M, Castagnoli A, Biondi A, Bernacchia A, Tazzari PL, D'Aurelio M, Parenti Castelli G, Formiggini G, Conte R, Bovina C, Lenaz G.

Free Radic Res. 2002 Apr;36(4):429-36.

PMID:
12069107
[PubMed - indexed for MEDLINE]
9.

Dual involvement of coenzyme Q10 in redox signaling and inhibition of death signaling in the rat heart mitochondria.

Yamamura T, Otani H, Nakao Y, Hattori R, Osako M, Imamura H, Das DK.

Antioxid Redox Signal. 2001 Feb;3(1):103-12.

PMID:
11291590
[PubMed - indexed for MEDLINE]
10.

C. elegans knockouts in ubiquinone biosynthesis genes result in different phenotypes during larval development.

Gavilán A, Asencio C, Cabello J, Rodríguez-Aguilera JC, Schnabel R, Navas P.

Biofactors. 2005;25(1-4):21-9.

PMID:
16873927
[PubMed - indexed for MEDLINE]
11.

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes.

Ishii N, Fujii M, Hartman PS, Tsuda M, Yasuda K, Senoo-Matsuda N, Yanase S, Ayusawa D, Suzuki K.

Nature. 1998 Aug 13;394(6694):694-7.

PMID:
9716135
[PubMed - indexed for MEDLINE]
12.

Water-soluble formulation of Coenzyme Q10 inhibits Bax-induced destabilization of mitochondria in mammalian cells.

Naderi J, Somayajulu-Nitu M, Mukerji A, Sharda P, Sikorska M, Borowy-Borowski H, Antonsson B, Pandey S.

Apoptosis. 2006 Aug;11(8):1359-69.

PMID:
16830230
[PubMed - indexed for MEDLINE]
13.

The role of the electron transport gene SDHC on lifespan and cancer.

Ishii N, Ishii T, Hartman PS.

Exp Gerontol. 2006 Oct;41(10):952-6. Epub 2006 Sep 7. Review.

PMID:
16962276
[PubMed - indexed for MEDLINE]
14.

Effect of coenzyme Q10 and vitamin E on brain energy metabolism in the animal model of Huntington's disease.

Kasparová S, Sumbalová Z, Bystrický P, Kucharská J, Liptaj T, Mlynárik V, Gvozdjáková A.

Neurochem Int. 2006 Jan;48(2):93-9. Epub 2005 Nov 14.

PMID:
16290265
[PubMed - indexed for MEDLINE]
15.

Effects of coenzyme Q(10) administration on its tissue concentrations, mitochondrial oxidant generation, and oxidative stress in the rat.

Kwong LK, Kamzalov S, Rebrin I, Bayne AC, Jana CK, Morris P, Forster MJ, Sohal RS.

Free Radic Biol Med. 2002 Sep 1;33(5):627-38.

PMID:
12208349
[PubMed - indexed for MEDLINE]
16.

Effect of oxidative stress on translocation of DAF-16 in oxygen-sensitive mutants, mev-1 and gas-1 of Caenorhabditis elegans.

Kondo M, Senoo-Matsuda N, Yanase S, Ishii T, Hartman PS, Ishii N.

Mech Ageing Dev. 2005 Jun-Jul;126(6-7):637-41. Epub 2005 Jan 8.

PMID:
15888316
[PubMed - indexed for MEDLINE]
17.

Restoration of the behavioral rates and lifespan in clk-1 mutant nematodes in response to exogenous coenzyme Q(10).

Takahashi M, Ogawara M, Shimizu T, Shirasawa T.

Exp Gerontol. 2012 Mar;47(3):276-9. doi: 10.1016/j.exger.2011.12.012. Epub 2012 Jan 5.

PMID:
22244837
[PubMed - indexed for MEDLINE]
18.

Coenzyme Q and the regulation of intracellular steady-state levels of superoxide in HL-60 cells.

González-Aragón D, Burón MI, López-Lluch G, Hermán MD, Gómez-Díaz C, Navas P, Villalba JM.

Biofactors. 2005;25(1-4):31-41.

PMID:
16873928
[PubMed - indexed for MEDLINE]
19.

The role of the electron transport SDHC gene on lifespan and cancer.

Ishii N, Ishii T, Hartman PS.

Mitochondrion. 2007 Feb-Apr;7(1-2):24-8. Epub 2006 Dec 3. Review.

PMID:
17321223
[PubMed - indexed for MEDLINE]
20.

Effect of lifelong coenzyme Q10 supplementation on age-related oxidative stress and mitochondrial function in liver and skeletal muscle of rats fed on a polyunsaturated fatty acid (PUFA)-rich diet.

Ochoa JJ, Quiles JL, López-Frías M, Huertas JR, Mataix J.

J Gerontol A Biol Sci Med Sci. 2007 Nov;62(11):1211-8.

PMID:
18000140
[PubMed - indexed for MEDLINE]

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