Similar articles for PMID: 14678746

Year	Number of Results
1995	2
1996	4
1997	5
1998	3
1999	7
2000	5
2001	15
2002	11
2003	8
2004	10
2005	6
2006	3
2007	3
2008	4
2009	2
2010	7
2011	6
2012	6
2013	5
2014	10
2015	1
2016	2
2017	1
2018	3
2019	4
2020	9
2021	8
2022	6
2023	3
2024	0

1

Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia.

Langheinrich U, Vacun G, Wagner T. Langheinrich U, et al. Toxicol Appl Pharmacol. 2003 Dec 15;193(3):370-82. doi: 10.1016/j.taap.2003.07.012. Toxicol Appl Pharmacol. 2003. PMID: 14678746

2

Evaluation of zebrafish embryos as a model for assessing inhibition of hERG.

Mittelstadt SW, Hemenway CL, Craig MP, Hove JR. Mittelstadt SW, et al. J Pharmacol Toxicol Methods. 2008 Mar-Apr;57(2):100-5. doi: 10.1016/j.vascn.2007.10.004. Epub 2007 Dec 23. J Pharmacol Toxicol Methods. 2008. PMID: 18291682

3

Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants.

Hassel D, Scholz EP, Trano N, Friedrich O, Just S, Meder B, Weiss DL, Zitron E, Marquart S, Vogel B, Karle CA, Seemann G, Fishman MC, Katus HA, Rottbauer W. Hassel D, et al. Circulation. 2008 Feb 19;117(7):866-75. doi: 10.1161/CIRCULATIONAHA.107.752220. Epub 2008 Feb 4. Circulation. 2008. PMID: 18250272

4

Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current.

London B, Trudeau MC, Newton KP, Beyer AK, Copeland NG, Gilbert DJ, Jenkins NA, Satler CA, Robertson GA. London B, et al. Circ Res. 1997 Nov;81(5):870-8. doi: 10.1161/01.res.81.5.870. Circ Res. 1997. PMID: 9351462

5

QT interval prolongation and cardiac risk assessment for novel drugs.

Picard S, Lacroix P. Picard S, et al. Curr Opin Investig Drugs. 2003 Mar;4(3):303-8. Curr Opin Investig Drugs. 2003. PMID: 12735231 Review.

6

Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.

Cavalli A, Poluzzi E, De Ponti F, Recanatini M. Cavalli A, et al. J Med Chem. 2002 Aug 29;45(18):3844-53. doi: 10.1021/jm0208875. J Med Chem. 2002. PMID: 12190308

7

A structural basis for drug-induced long QT syndrome.

Mitcheson JS, Chen J, Lin M, Culberson C, Sanguinetti MC. Mitcheson JS, et al. Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12329-33. doi: 10.1073/pnas.210244497. Proc Natl Acad Sci U S A. 2000. PMID: 11005845 Free PMC article.

8

The anti-malarial drug halofantrine and its metabolite N-desbutylhalofantrine block HERG potassium channels.

Mbai M, Rajamani S, January CT. Mbai M, et al. Cardiovasc Res. 2002 Sep;55(4):799-805. doi: 10.1016/s0008-6363(02)00448-0. Cardiovasc Res. 2002. PMID: 12176129

9

The hERG channel activator, RPR260243, enhances protective I_Kr current early in the refractory period reducing arrhythmogenicity in zebrafish hearts.

Shi YP, Pang Z, Venkateshappa R, Gunawan M, Kemp J, Truong E, Chang C, Lin E, Shafaattalab S, Faizi S, Rayani K, Tibbits GF, Claydon VE, Claydon TW. Shi YP, et al. Am J Physiol Heart Circ Physiol. 2020 Aug 1;319(2):H251-H261. doi: 10.1152/ajpheart.00038.2020. Epub 2020 Jun 19. Am J Physiol Heart Circ Physiol. 2020. PMID: 32559136 Free article.

10

Molecular determinants of high-affinity drug binding to HERG channels.

Mitcheson JS, Perry MD. Mitcheson JS, et al. Curr Opin Drug Discov Devel. 2003 Sep;6(5):667-74. Curr Opin Drug Discov Devel. 2003. PMID: 14579516 Review.

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