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Apoptosis induced by p75NTR overexpression requires Jun kinase-dependent phosphorylation of Bad.

Bhakar AL, Howell JL, Paul CE, Salehi AH, Becker EB, Said F, Bonni A, Barker PA.

J Neurosci. 2003 Dec 10;23(36):11373-81.


Glioma invasion mediated by the p75 neurotrophin receptor (p75NTR/CD271) requires regulated interaction with PDLIM1.

Ahn BY, Saldanha-Gama RF, Rahn JJ, Hao X, Zhang J, Dang NH, Alshehri M, Robbins SM, Senger DL.

Oncogene. 2015 Jun 29. doi: 10.1038/onc.2015.199. [Epub ahead of print]


p75NTR-dependent Rac1 activation requires receptor cleavage and activation of an NRAGE and NEDD9 signaling cascade.

Zeinieh M, Salehi A, Rajkumar V, Barker PA.

J Cell Sci. 2015 Feb 1;128(3):447-59.


p75 neurotrophin receptor and fenretinide-induced signaling in neuroblastoma.

Ganeshan VR, Schor NF.

Cancer Chemother Pharmacol. 2014 Feb;73(2):271-9. doi: 10.1007/s00280-013-2355-y. Epub 2013 Nov 20.


Ethanol induces cell cycle arrest and triggers apoptosis via Sp1-dependent p75NTR expression in human neuroblastoma cells.

Do H, Park HJ, Sohn EH, Kim BO, Um SH, Kwak JH, Moon EY, Rhee DK, Pyo S.

Cell Biol Toxicol. 2013 Oct;29(5):365-80. doi: 10.1007/s10565-013-9260-3. Epub 2013 Sep 12.


p75NTR signal transduction suppressed by BFAR and p75NTR interactions.

Li H, Shi H, Huo K.

Sci China Life Sci. 2012 Apr;55(4):367-74. doi: 10.1007/s11427-012-4306-y. Epub 2012 May 9.


Suppression of p75 neurotrophin receptor surface expression with intrabodies influences Bcl-xL mRNA expression and neurite outgrowth in PC12 cells.

Zhang C, Helmsing S, Zagrebelsky M, Schirrmann T, Marschall AL, Schüngel M, Korte M, Hust M, Dübel S.

PLoS One. 2012;7(1):e30684. doi: 10.1371/journal.pone.0030684. Epub 2012 Jan 24.


p75NTR is mainly responsible for Aβ toxicity but not for its internalization: a primary study.

Yu H, Yang M, Wang Y, Xiao R, Zhou XF.

Neurol Sci. 2012 Oct;33(5):1043-50. doi: 10.1007/s10072-011-0892-x. Epub 2011 Dec 20.


Chopper is prodeath regardless of the effect of p75ICD on sensitivity to oxidative stress.

Qazi A, Halterman MW, Mi Z, Zhang T, Schor NF.

Oxid Med Cell Longev. 2011;2011:391659. doi: 10.1155/2011/391659. Epub 2011 Sep 5.


Trk-dependent ADAM17 activation facilitates neurotrophin survival signaling.

Kommaddi RP, Thomas R, Ceni C, Daigneault K, Barker PA.

FASEB J. 2011 Jun;25(6):2061-70. doi: 10.1096/fj.10-173740. Epub 2011 Mar 16.


p75 neurotrophin receptor mediates apoptosis in transit-amplifying cells and its overexpression restores cell death in psoriatic keratinocytes.

Truzzi F, Marconi A, Atzei P, Panza MC, Lotti R, Dallaglio K, Tiberio R, Palazzo E, Vaschieri C, Pincelli C.

Cell Death Differ. 2011 Jun;18(6):948-58. doi: 10.1038/cdd.2010.162. Epub 2010 Dec 10.


Stress-induced expression of the p75 neurotrophin receptor is regulated by O-GlcNAcylation of the Sp1 transcription factor.

Kommaddi RP, Dickson KM, Barker PA.

J Neurochem. 2011 Feb;116(3):396-405. doi: 10.1111/j.1471-4159.2010.07120.x. Epub 2010 Dec 13.


Role of tyrosine phosphorylation in the antioxidant effects of the p75 neurotrophin receptor.

Zhang T, Mi Z, Schor NF.

Oxid Med Cell Longev. 2009 Sep-Oct;2(4):238-46. doi: 10.4161/oxim.2.4.9745.


Bag1-L is a phosphorylation-dependent coactivator of c-Jun during neuronal apoptosis.

Da Costa CR, Villadiego J, Sancho R, Fontana X, Packham G, Nateri AS, Behrens A.

Mol Cell Biol. 2010 Aug;30(15):3842-52. doi: 10.1128/MCB.01610-09. Epub 2010 Jun 1.


p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-alpha-converting enzyme/ADAM17.

Kenchappa RS, Tep C, Korade Z, Urra S, Bronfman FC, Yoon SO, Carter BD.

J Biol Chem. 2010 Jun 25;285(26):20358-68. doi: 10.1074/jbc.M109.082834. Epub 2010 Apr 26.


Necdin and TrkA contribute to modulation by p75NTR of resistance to oxidant stress.

Ingraham CA, Schor NF.

Exp Cell Res. 2009 Dec 10;315(20):3532-42. doi: 10.1016/j.yexcr.2009.10.001. Epub 2009 Oct 8.


A novel peptide, colivelin, prevents alcohol-induced apoptosis in fetal brain of C57BL/6 mice: signaling pathway investigations.

Sari Y, Chiba T, Yamada M, Rebec GV, Aiso S.

Neuroscience. 2009 Dec 29;164(4):1653-64. doi: 10.1016/j.neuroscience.2009.09.049. Epub 2009 Sep 25.


p75NTR-dependent modulation of cellular handling of reactive oxygen species.

Mi Z, Rogers DA, Mirnics ZK, Schor NF.

J Neurochem. 2009 Jul;110(1):295-306. doi: 10.1111/j.1471-4159.2009.06137.x. Epub 2009 Apr 30.


Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression.

Alavian KN, Sgadò P, Alberi L, Subramaniam S, Simon HH.

Neural Dev. 2009 Mar 16;4:11. doi: 10.1186/1749-8104-4-11.

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