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Results: 1 to 20 of 88

1.

Chemoresistance in human ovarian cancer: the role of apoptotic regulators.

Fraser M, Leung B, Jahani-Asl A, Yan X, Thompson WE, Tsang BK.

Reprod Biol Endocrinol. 2003 Oct 7;1:66. Review.

PMID:
14609433
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase/Akt pathway.

Cheng JQ, Jiang X, Fraser M, Li M, Dan HC, Sun M, Tsang BK.

Drug Resist Updat. 2002 Jul-Aug;5(3-4):131-46. Review.

PMID:
12237081
[PubMed - indexed for MEDLINE]
3.

XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells.

Asselin E, Mills GB, Tsang BK.

Cancer Res. 2001 Mar 1;61(5):1862-8.

PMID:
11280739
[PubMed - indexed for MEDLINE]
Free Article
4.

p53 is a determinant of X-linked inhibitor of apoptosis protein/Akt-mediated chemoresistance in human ovarian cancer cells.

Fraser M, Leung BM, Yan X, Dan HC, Cheng JQ, Tsang BK.

Cancer Res. 2003 Nov 1;63(21):7081-8.

PMID:
14612499
[PubMed - indexed for MEDLINE]
Free Article
5.

A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.

Martelli AM, Tazzari PL, Tabellini G, Bortul R, Billi AM, Manzoli L, Ruggeri A, Conte R, Cocco L.

Leukemia. 2003 Sep;17(9):1794-805.

PMID:
12970779
[PubMed - indexed for MEDLINE]
6.

[Integrins, cell response to anti-tumor agents and chemoresistance].

Maubant S, Staedel C, Gauduchon P.

Bull Cancer. 2002 Nov;89(11):923-34. Review. French.

PMID:
12495880
[PubMed - indexed for MEDLINE]
7.

Down-regulation of X-linked inhibitor of apoptosis protein induces apoptosis in chemoresistant human ovarian cancer cells.

Sasaki H, Sheng Y, Kotsuji F, Tsang BK.

Cancer Res. 2000 Oct 15;60(20):5659-66.

PMID:
11059757
[PubMed - indexed for MEDLINE]
Free Article
8.

Caspase 9 is required for p53-dependent apoptosis and chemosensitivity in a human ovarian cancer cell line.

Wu GS, Ding Z.

Oncogene. 2002 Jan 3;21(1):1-8.

PMID:
11791171
[PubMed - indexed for MEDLINE]
Free Article
9.

Sensitization of tumor cells to Apo2 ligand/TRAIL-induced apoptosis by inhibition of casein kinase II.

Ravi R, Bedi A.

Cancer Res. 2002 Aug 1;62(15):4180-5.

PMID:
12154014
[PubMed - indexed for MEDLINE]
Free Article
10.

Aurora-A induces cell survival and chemoresistance by activation of Akt through a p53-dependent manner in ovarian cancer cells.

Yang H, He L, Kruk P, Nicosia SV, Cheng JQ.

Int J Cancer. 2006 Nov 15;119(10):2304-12.

PMID:
16894566
[PubMed - indexed for MEDLINE]
11.

Differential sensitivity to apoptosis between the human small and large intestinal mucosae: linkage with segment-specific regulation of BCL-2 homologs and involvement of signaling pathways.

Gauthier R, Laprise P, Cardin E, Harnois C, Plourde A, Reed JC, Vézina A, Vachon PH.

J Cell Biochem. 2001;82(2):339-55.

PMID:
11527158
[PubMed - indexed for MEDLINE]
12.

Serum bioactive lysophospholipids prevent TRAIL-induced apoptosis via PI3K/Akt-dependent cFLIP expression and Bad phosphorylation.

Kang YC, Kim KM, Lee KS, Namkoong S, Lee SJ, Han JA, Jeoung D, Ha KS, Kwon YG, Kim YM.

Cell Death Differ. 2004 Dec;11(12):1287-98.

PMID:
15297884
[PubMed - indexed for MEDLINE]
Free Article
13.

Src tyrosine kinase promotes survival and resistance to chemotherapeutics in a mouse ovarian cancer cell line.

Pengetnze Y, Steed M, Roby KF, Terranova PF, Taylor CC.

Biochem Biophys Res Commun. 2003 Sep 19;309(2):377-83.

PMID:
12951060
[PubMed - indexed for MEDLINE]
14.

Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function.

Fraser M, Bai T, Tsang BK.

Int J Cancer. 2008 Feb 1;122(3):534-46.

PMID:
17918180
[PubMed - indexed for MEDLINE]
15.

TRAIL triggers apoptosis in human malignant glioma cells through extrinsic and intrinsic pathways.

Song JH, Song DK, Pyrzynska B, Petruk KC, Van Meir EG, Hao C.

Brain Pathol. 2003 Oct;13(4):539-53.

PMID:
14655759
[PubMed - indexed for MEDLINE]
16.

Selective Akt inactivation and tumor necrosis actor-related apoptosis-inducing ligand sensitization of renal cancer cells by low concentrations of paclitaxel.

Asakuma J, Sumitomo M, Asano T, Asano T, Hayakawa M.

Cancer Res. 2003 Mar 15;63(6):1365-70.

PMID:
12649200
[PubMed - indexed for MEDLINE]
Free Article
17.

Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals.

O'Gorman DM, McKenna SL, McGahon AJ, Knox KA, Cotter TG.

Leukemia. 2000 Apr;14(4):602-11.

PMID:
10764145
[PubMed - indexed for MEDLINE]
18.

Human intestinal epithelial crypt cell survival and death: Complex modulations of Bcl-2 homologs by Fak, PI3-K/Akt-1, MEK/Erk, and p38 signaling pathways.

Harnois C, Demers MJ, Bouchard V, Vallée K, Gagné D, Fujita N, Tsuruo T, Vézina A, Beaulieu JF, Côté A, Vachon PH.

J Cell Physiol. 2004 Feb;198(2):209-22.

PMID:
14603523
[PubMed - indexed for MEDLINE]
19.

Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism.

Garrouste F, Remacle-Bonnet M, Fauriat C, Marvaldi J, Luis J, Pommier G.

Cell Death Differ. 2002 Jul;9(7):768-79.

PMID:
12058282
[PubMed - indexed for MEDLINE]
Free Article
20.

Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein.

Abedini MR, Muller EJ, Bergeron R, Gray DA, Tsang BK.

Oncogene. 2010 Jan 7;29(1):11-25. doi: 10.1038/onc.2009.300. Epub 2009 Oct 5.

PMID:
19802016
[PubMed - indexed for MEDLINE]

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