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Items: 1 to 20 of 173

1.

Monoclonal antibodies generated in carbonic anhydrase IX-deficient mice recognize different domains of tumour-associated hypoxia-induced carbonic anhydrase IX.

Zat'ovicová M, Tarábková K, Svastová E, Gibadulinová A, Mucha V, Jakubícková L, Biesová Z, Rafajová M, Ortova Gut M, Parkkila S, Parkkila AK, Waheed A, Sly WS, Horak I, Pastorek J, Pastoreková S.

J Immunol Methods. 2003 Nov;282(1-2):117-34.

PMID:
14604546
2.

Hypoxia-inducible expression of the mouse carbonic anhydrase IX demonstrated by new monoclonal antibodies.

Takacova M, Barathova M, Hulikova A, Ohradanova A, Kopacek J, Parkkila S, Pastorek J, Pastorekova S, Zatovicova M.

Int J Oncol. 2007 Nov;31(5):1103-10.

PMID:
17912436
3.

Carbonic anhydrase IX as an anticancer therapy target: preclinical evaluation of internalizing monoclonal antibody directed to catalytic domain.

Zatovicova M, Jelenska L, Hulikova A, Csaderova L, Ditte Z, Ditte P, Goliasova T, Pastorek J, Pastorekova S.

Curr Pharm Des. 2010;16(29):3255-63. Review.

PMID:
20819068
4.

Carbonic anhydrase IX (CA IX) mediates tumor cell interactions with microenvironment.

Zavadova Z, Zavada J.

Oncol Rep. 2005 May;13(5):977-82.

PMID:
15809767
5.

Human monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours.

Ahlskog JK, Schliemann C, Mårlind J, Qureshi U, Ammar A, Pedley RB, Neri D.

Br J Cancer. 2009 Aug 18;101(4):645-57. doi: 10.1038/sj.bjc.6605200. Epub 2009 Jul 21.

6.

Stabilization of antibody structure upon association to a human carbonic anhydrase IX epitope studied by X-ray crystallography, microcalorimetry, and molecular dynamics simulations.

Král V, Mader P, Collard R, Fábry M, Horejsí M, Rezácová P, Kozísek M, Závada J, Sedlácek J, Rulísek L, Brynda J.

Proteins. 2008 May 15;71(3):1275-87.

PMID:
18041760
7.
8.
9.

Unique biological properties of catalytic domain directed human anti-CAIX antibodies discovered through phage-display technology.

Xu C, Lo A, Yammanuru A, Tallarico AS, Brady K, Murakami A, Barteneva N, Zhu Q, Marasco WA.

PLoS One. 2010 Mar 10;5(3):e9625. doi: 10.1371/journal.pone.0009625.

10.

Monoclonal antibodies raised against 167-180 aa sequence of human carbonic anhydrase XII inhibit its enzymatic activity.

Dekaminaviciute D, Kairys V, Zilnyte M, Petrikaite V, Jogaite V, Matuliene J, Gudleviciene Z, Vullo D, Supuran CT, Zvirbliene A.

J Enzyme Inhib Med Chem. 2014 Dec;29(6):804-10. doi: 10.3109/14756366.2013.856424. Epub 2014 Jan 9.

PMID:
24400872
11.

Drug design studies of the novel antitumor targets carbonic anhydrase IX and XII.

Guler OO, De Simone G, Supuran CT.

Curr Med Chem. 2010;17(15):1516-26. Review.

PMID:
20166929
12.

Carbonic anhydrase IX as a target for designing novel anticancer drugs.

Monti SM, Supuran CT, De Simone G.

Curr Med Chem. 2012;19(6):821-30. Review.

PMID:
22214452
13.

Carbonic anhydrase IX: Biochemical and crystallographic characterization of a novel antitumor target.

De Simone G, Supuran CT.

Biochim Biophys Acta. 2010 Feb;1804(2):404-9. doi: 10.1016/j.bbapap.2009.07.027. Epub 2009 Aug 11. Review.

PMID:
19679200
14.

G250: a carbonic anhydrase IX monoclonal antibody.

Lam JS, Pantuck AJ, Belldegrun AS, Figlin RA.

Curr Oncol Rep. 2005 Mar;7(2):109-15. Review.

PMID:
15717944
15.

Development and characterization of new monoclonal antibodies against human recombinant CA XII.

Dekaminaviciute D, Lasickiene R, Parkkila S, Jogaite V, Matuliene J, Matulis D, Zvirbliene A.

Biomed Res Int. 2014;2014:309307. doi: 10.1155/2014/309307. Epub 2014 May 20.

16.

Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: from biology to clinical use.

Pastorek J, Pastorekova S.

Semin Cancer Biol. 2015 Apr;31:52-64. doi: 10.1016/j.semcancer.2014.08.002. Epub 2014 Aug 10. Review.

PMID:
25117006
17.

Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma.

Chia SK, Wykoff CC, Watson PH, Han C, Leek RD, Pastorek J, Gatter KC, Ratcliffe P, Harris AL.

J Clin Oncol. 2001 Aug 15;19(16):3660-8.

PMID:
11504747
18.

Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX.

Hulikova A, Zatovicova M, Svastova E, Ditte P, Brasseur R, Kettmann R, Supuran CT, Kopacek J, Pastorek J, Pastorekova S.

FEBS Lett. 2009 Nov 19;583(22):3563-8. doi: 10.1016/j.febslet.2009.10.060. Epub 2009 Oct 25.

19.

Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes.

Hilvo M, Baranauskiene L, Salzano AM, Scaloni A, Matulis D, Innocenti A, Scozzafava A, Monti SM, Di Fiore A, De Simone G, Lindfors M, Jänis J, Valjakka J, Pastoreková S, Pastorek J, Kulomaa MS, Nordlund HR, Supuran CT, Parkkila S.

J Biol Chem. 2008 Oct 10;283(41):27799-809. doi: 10.1074/jbc.M800938200. Epub 2008 Aug 13.

20.

Carbonic anhydrase gene expression in CA II-deficient (Car2-/-) and CA IX-deficient (Car9-/-) mice.

Pan P, Leppilampi M, Pastorekova S, Pastorek J, Waheed A, Sly WS, Parkkila S.

J Physiol. 2006 Mar 1;571(Pt 2):319-27. Epub 2006 Jan 5.

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