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Polymorphisms in the genes encoding members of the tristetraprolin family of human tandem CCCH zinc finger proteins.

Blackshear PJ, Phillips RS, Vazquez-Matias J, Mohrenweiser H.

Prog Nucleic Acid Res Mol Biol. 2003;75:43-68.


Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling.

Phillips RS, Ramos SB, Blackshear PJ.

J Biol Chem. 2002 Mar 29;277(13):11606-13. Epub 2002 Jan 16.


Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover.

Blackshear PJ.

Biochem Soc Trans. 2002 Nov;30(Pt 6):945-52. Review.


The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis.

Carrick DM, Lai WS, Blackshear PJ.

Arthritis Res Ther. 2004;6(6):248-64. Epub 2004 Oct 8. Review.


Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin family.

Stumpo DJ, Byrd NA, Phillips RS, Ghosh S, Maronpot RR, Castranio T, Meyers EN, Mishina Y, Blackshear PJ.

Mol Cell Biol. 2004 Jul;24(14):6445-55.


Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteins.

Blackshear PJ, Phillips RS, Ghosh S, Ramos SB, Richfield EK, Lai WS.

Biol Reprod. 2005 Aug;73(2):297-307. Epub 2005 Apr 6. Erratum in: Biol Reprod. 2005 Nov;73(5):1072. Ramos, Silvia V B [corrected to Ramos, Silvia B V].


Identification of four CCCH zinc finger proteins in Xenopus, including a novel vertebrate protein with four zinc fingers and severely restricted expression.

De J, Lai WS, Thorn JM, Goldsworthy SM, Liu X, Blackwell TK, Blackshear PJ.

Gene. 1999 Mar 4;228(1-2):133-45.


Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates.

Blackshear PJ, Lai WS, Kennington EA, Brewer G, Wilson GM, Guan X, Zhou P.

J Biol Chem. 2003 May 30;278(22):19947-55. Epub 2003 Mar 14.


Influence of nonameric AU-rich tristetraprolin-binding sites on mRNA deadenylation and turnover.

Lai WS, Carrick DM, Blackshear PJ.

J Biol Chem. 2005 Oct 7;280(40):34365-77. Epub 2005 Aug 1.


Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.

Lai WS, Carballo E, Strum JR, Kennington EA, Phillips RS, Blackshear PJ.

Mol Cell Biol. 1999 Jun;19(6):4311-23.


Cytoplasmic localization of tristetraprolin involves 14-3-3-dependent and -independent mechanisms.

Johnson BA, Stehn JR, Yaffe MB, Blackwell TK.

J Biol Chem. 2002 May 17;277(20):18029-36. Epub 2002 Mar 8.


Insulin increases tristetraprolin and decreases VEGF gene expression in mouse 3T3-L1 adipocytes.

Cao H, Urban JF Jr, Anderson RA.

Obesity (Silver Spring). 2008 Jun;16(6):1208-18. doi: 10.1038/oby.2008.65. Epub 2008 Apr 3.

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