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Results: 1 to 20 of 163

1.

Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway.

Shoham NG, Centola M, Mansfield E, Hull KM, Wood G, Wise CA, Kastner DL.

Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13501-6. Epub 2003 Oct 31.

PMID:
14595024
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder.

Wise CA, Gillum JD, Seidman CE, Lindor NM, Veile R, Bashiardes S, Lovett M.

Hum Mol Genet. 2002 Apr 15;11(8):961-9.

PMID:
11971877
[PubMed - indexed for MEDLINE]
Free Article
3.

A common pathway in periodic fever syndromes.

McDermott MF.

Trends Immunol. 2004 Sep;25(9):457-60. Review.

PMID:
15324736
[PubMed - indexed for MEDLINE]
4.

Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants.

Yu JW, Fernandes-Alnemri T, Datta P, Wu J, Juliana C, Solorzano L, McCormick M, Zhang Z, Alnemri ES.

Mol Cell. 2007 Oct 26;28(2):214-27.

PMID:
17964261
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Pyrin Modulates the Intracellular Distribution of PSTPIP1.

Waite AL, Schaner P, Richards N, Balci-Peynircioglu B, Masters SL, Brydges SD, Fox M, Hong A, Yilmaz E, Kastner DL, Reinherz EL, Gumucio DL.

PLoS One. 2009 Jul 7;4(7):e6147. doi: 10.1371/journal.pone.0006147.

PMID:
19584923
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production.

Chae JJ, Wood G, Masters SL, Richard K, Park G, Smith BJ, Kastner DL.

Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9982-7. Epub 2006 Jun 19.

PMID:
16785446
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing.

Papin S, Cuenin S, Agostini L, Martinon F, Werner S, Beer HD, Grütter C, Grütter M, Tschopp J.

Cell Death Differ. 2007 Aug;14(8):1457-66. Epub 2007 Apr 13.

PMID:
17431422
[PubMed - indexed for MEDLINE]
Free Article
8.

Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis.

Richards N, Schaner P, Diaz A, Stuckey J, Shelden E, Wadhwa A, Gumucio DL.

J Biol Chem. 2001 Oct 19;276(42):39320-9. Epub 2001 Aug 9.

PMID:
11498534
[PubMed - indexed for MEDLINE]
Free Article
9.

Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins.

Wang D, Höing S, Patterson HC, Ahmad UM, Rathinam VA, Rajewsky K, Fitzgerald KA, Golenbock DT.

J Biol Chem. 2013 Feb 15;288(7):4594-601. doi: 10.1074/jbc.M112.443077. Epub 2013 Jan 4.

PMID:
23293022
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Pyrin, product of the MEFV locus, interacts with the proapoptotic protein, Siva.

Balci-Peynircioglu B, Waite AL, Hu C, Richards N, Staubach-Grosse A, Yilmaz E, Gumucio DL.

J Cell Physiol. 2008 Sep;216(3):595-602. doi: 10.1002/jcp.21435.

PMID:
18330885
[PubMed - indexed for MEDLINE]
11.

Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis.

Chae JJ, Komarow HD, Cheng J, Wood G, Raben N, Liu PP, Kastner DL.

Mol Cell. 2003 Mar;11(3):591-604.

PMID:
12667444
[PubMed - indexed for MEDLINE]
Free Article
12.

Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation.

Cong F, Spencer S, Côté JF, Wu Y, Tremblay ML, Lasky LA, Goff SP.

Mol Cell. 2000 Dec;6(6):1413-23.

PMID:
11163214
[PubMed - indexed for MEDLINE]
Free Article
13.

Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway.

Bassermann F, Jahn T, Miething C, Seipel P, Bai RY, Coutinho S, Tybulewicz VL, Peschel C, Duyster J.

J Biol Chem. 2002 Apr 5;277(14):12437-45. Epub 2002 Jan 14.

PMID:
11790798
[PubMed - indexed for MEDLINE]
Free Article
14.

Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC.

Dowds TA, Masumoto J, Zhu L, Inohara N, Núñez G.

J Biol Chem. 2004 May 21;279(21):21924-8. Epub 2004 Mar 12.

PMID:
15020601
[PubMed - indexed for MEDLINE]
Free Article
15.

Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product.

Dowds TA, Masumoto J, Chen FF, Ogura Y, Inohara N, Núñez G.

Biochem Biophys Res Commun. 2003 Mar 14;302(3):575-80.

PMID:
12615073
[PubMed - indexed for MEDLINE]
16.

The familial Mediterranean fever protein, pyrin, associates with microtubules and colocalizes with actin filaments.

Mansfield E, Chae JJ, Komarow HD, Brotz TM, Frucht DM, Aksentijevich I, Kastner DL.

Blood. 2001 Aug 1;98(3):851-9.

PMID:
11468188
[PubMed - indexed for MEDLINE]
Free Article
17.

Pyrin and ASC co-localize to cellular sites that are rich in polymerizing actin.

Waite AL, Schaner P, Hu C, Richards N, Balci-Peynircioglu B, Hong A, Fox M, Gumucio DL.

Exp Biol Med (Maywood). 2009 Jan;234(1):40-52. doi: 10.3181/0806-RM-184.

PMID:
19109554
[PubMed - indexed for MEDLINE]
18.

PSTPIP is a substrate of PTP-PEST and serves as a scaffold guiding PTP-PEST toward a specific dephosphorylation of WASP.

Côté JF, Chung PL, Théberge JF, Hallé M, Spencer S, Lasky LA, Tremblay ML.

J Biol Chem. 2002 Jan 25;277(4):2973-86. Epub 2001 Nov 15.

PMID:
11711533
[PubMed - indexed for MEDLINE]
Free Article
19.

The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment.

Chae JJ, Wood G, Richard K, Jaffe H, Colburn NT, Masters SL, Gumucio DL, Shoham NG, Kastner DL.

Blood. 2008 Sep 1;112(5):1794-803. doi: 10.1182/blood-2008-01-134932. Epub 2008 Jun 24.

PMID:
18577712
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Mitotic phosphorylation rescues Abl from F-actin-mediated inhibition.

Woodring PJ, Hunter T, Wang JY.

J Biol Chem. 2005 Mar 18;280(11):10318-25. Epub 2005 Jan 4.

PMID:
15632178
[PubMed - indexed for MEDLINE]
Free Article

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