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Results: 1 to 20 of 132

1.

The tumor-suppressive functions of the human INK4A locus.

Voorhoeve PM, Agami R.

Cancer Cell. 2003 Oct;4(4):311-9.

PMID:
14585358
[PubMed - indexed for MEDLINE]
Free Article
2.

Profiles of the 2 INK4a gene products, p16 and p14ARF, in human reference urothelium and bladder carcinomas, according to pRb and p53 protein status.

Le Frère-Belda MA, Gil Diez de Medina S, Daher A, Martin N, Albaud B, Heudes D, Abbou CC, Thiery JP, Zafrani ES, Radvanyi F, Chopin D.

Hum Pathol. 2004 Jul;35(7):817-24.

PMID:
15257544
[PubMed - indexed for MEDLINE]
3.

Unraveling human tumor suppressor pathways: a tale of the INK4A locus.

Voorhoeve PM, Agami R.

Cell Cycle. 2004 May;3(5):616-20. Epub 2004 May 15. Review.

PMID:
15044859
[PubMed - indexed for MEDLINE]
Free Article
4.

P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells.

Oruetxebarria I, Venturini F, Kekarainen T, Houweling A, Zuijderduijn LM, Mohd-Sarip A, Vries RG, Hoeben RC, Verrijzer CP.

J Biol Chem. 2004 Jan 30;279(5):3807-16. Epub 2003 Nov 6.

PMID:
14604992
[PubMed - indexed for MEDLINE]
Free Article
5.

The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.

Sharpless NE, Ramsey MR, Balasubramanian P, Castrillon DH, DePinho RA.

Oncogene. 2004 Jan 15;23(2):379-85.

PMID:
14724566
[PubMed - indexed for MEDLINE]
6.

Recovery of function in osteoarthritic chondrocytes induced by p16INK4a-specific siRNA in vitro.

Zhou HW, Lou SQ, Zhang K.

Rheumatology (Oxford). 2004 May;43(5):555-68. Epub 2004 Mar 16.

PMID:
15026580
[PubMed - indexed for MEDLINE]
Free Article
7.

Induction of p16INK4A mediated by beta-catenin in a TCF4-independent manner: implications for alterations in p16INK4A and pRb expression during trans-differentiation of endometrial carcinoma cells.

Saegusa M, Hashimura M, Kuwata T, Hamano M, Okayasu I.

Int J Cancer. 2006 Nov 15;119(10):2294-303.

PMID:
16858682
[PubMed - indexed for MEDLINE]
8.

Tumor suppressor p16INK4a determines sensitivity of human cells to transformation by cooperating cellular oncogenes.

Drayton S, Rowe J, Jones R, Vatcheva R, Cuthbert-Heavens D, Marshall J, Fried M, Peters G.

Cancer Cell. 2003 Oct;4(4):301-10.

PMID:
14585357
[PubMed - indexed for MEDLINE]
Free Article
9.

p53-Dependent and -independent functions of the Arf tumor suppressor.

Sherr CJ, Bertwistle D, DEN Besten W, Kuo ML, Sugimoto M, Tago K, Williams RT, Zindy F, Roussel MF.

Cold Spring Harb Symp Quant Biol. 2005;70:129-37. Review.

PMID:
16869746
[PubMed - indexed for MEDLINE]
10.

Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines.

Park YB, Park MJ, Kimura K, Shimizu K, Lee SH, Yokota J.

Cancer Genet Cytogenet. 2002 Mar;133(2):105-11.

PMID:
11943335
[PubMed - indexed for MEDLINE]
11.

The inhibitor of cyclin-dependent kinase 4a/alternative reading frame (INK4a/ARF) locus encoded proteins p16INK4a and p19ARF repress cyclin D1 transcription through distinct cis elements.

D'Amico M, Wu K, Fu M, Rao M, Albanese C, Russell RG, Lian H, Bregman D, White MA, Pestell RG.

Cancer Res. 2004 Jun 15;64(12):4122-30.

PMID:
15205322
[PubMed - indexed for MEDLINE]
Free Article
13.

Role of the alternative INK4A proteins in human keratinocyte senescence: evidence for the specific inactivation of p16INK4A upon immortalization.

Munro J, Stott FJ, Vousden KH, Peters G, Parkinson EK.

Cancer Res. 1999 Jun 1;59(11):2516-21.

PMID:
10363964
[PubMed - indexed for MEDLINE]
Free Article
14.

FBXL16 is a novel E2F1-regulated gene commonly upregulated in p16INK4A- and p14ARF-silenced HeLa cells.

Sato K, Kusama Y, Tategu M, Yoshida K.

Int J Oncol. 2010 Feb;36(2):479-90.

PMID:
20043084
[PubMed - indexed for MEDLINE]
15.

Genomic instability, mutations and expression analysis of the tumour suppressor genes p14(ARF), p15(INK4b), p16(INK4a) and p53 in actinic keratosis.

Kanellou P, Zaravinos A, Zioga M, Stratigos A, Baritaki S, Soufla G, Zoras O, Spandidos DA.

Cancer Lett. 2008 Jun 8;264(1):145-61. doi: 10.1016/j.canlet.2008.01.042. Epub 2008 Mar 10.

PMID:
18331779
[PubMed - indexed for MEDLINE]
16.

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization.

Carnero A, Hudson JD, Price CM, Beach DH.

Nat Cell Biol. 2000 Mar;2(3):148-55.

PMID:
10707085
[PubMed - indexed for MEDLINE]
17.

E2F transcriptional repressor complexes are critical downstream targets of p19(ARF)/p53-induced proliferative arrest.

Rowland BD, Denissov SG, Douma S, Stunnenberg HG, Bernards R, Peeper DS.

Cancer Cell. 2002 Jul;2(1):55-65.

PMID:
12150825
[PubMed - indexed for MEDLINE]
Free Article
18.

Correlation between p14(ARF)/p16(INK4A) expression and HPV infection in uterine cervical cancer.

Kanao H, Enomoto T, Ueda Y, Fujita M, Nakashima R, Ueno Y, Miyatake T, Yoshizaki T, Buzard GS, Kimura T, Yoshino K, Murata Y.

Cancer Lett. 2004 Sep 15;213(1):31-7.

PMID:
15312681
[PubMed - indexed for MEDLINE]
19.

5' cytosine-phospho-guanine island methylation is responsible for p14ARF inactivation and inversely correlates with p53 overexpression in resected non-small cell lung cancer.

Hsu HS, Wang YC, Tseng RC, Chang JW, Chen JT, Shih CM, Chen CY, Wang YC.

Clin Cancer Res. 2004 Jul 15;10(14):4734-41.

PMID:
15269146
[PubMed - indexed for MEDLINE]
Free Article
20.

Role of the INK4a locus in tumor suppression and cell mortality.

Serrano M, Lee H, Chin L, Cordon-Cardo C, Beach D, DePinho RA.

Cell. 1996 Apr 5;85(1):27-37.

PMID:
8620534
[PubMed - indexed for MEDLINE]
Free Article

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